LD50 = 1200 mg/kg (rat, subcutaneous). May be harmful if swallowed. May act as an irritant. Adverse reactions include hypotension, ECG changes, diarrhea, urinary retention, CNS depression and respiratory depression.
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Ceritinib | Magnesium sulfate may increase the bradycardic activities of Ceritinib. |
| Ivabradine | Magnesium sulfate may increase the bradycardic activities of Ivabradine. |
| Ruxolitinib | Ruxolitinib may increase the bradycardic activities of Magnesium sulfate. |
| Buprenorphine | Magnesium sulfate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Magnesium sulfate. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Magnesium sulfate. |
| Botulinum toxin type B | The therapeutic efficacy of Botulinum toxin type B can be increased when used in combination with Magnesium sulfate. |
| Botulinum toxin type A | The therapeutic efficacy of Botulinum toxin type A can be increased when used in combination with Magnesium sulfate. |
| Fluvoxamine | The therapeutic efficacy of Fluvoxamine can be increased when used in combination with Magnesium sulfate. |
| Baclofen | The therapeutic efficacy of Baclofen can be increased when used in combination with Magnesium sulfate. |
| Lorazepam | The therapeutic efficacy of Lorazepam can be increased when used in combination with Magnesium sulfate. |
| Ethchlorvynol | The therapeutic efficacy of Ethchlorvynol can be increased when used in combination with Magnesium sulfate. |
| Tramadol | The therapeutic efficacy of Tramadol can be increased when used in combination with Magnesium sulfate. |
| Succinylcholine | The therapeutic efficacy of Succinylcholine can be increased when used in combination with Magnesium sulfate. |
| Reserpine | The therapeutic efficacy of Reserpine can be increased when used in combination with Magnesium sulfate. |
| Citalopram | The therapeutic efficacy of Citalopram can be increased when used in combination with Magnesium sulfate. |
| Eletriptan | The therapeutic efficacy of Eletriptan can be increased when used in combination with Magnesium sulfate. |
| Enflurane | The therapeutic efficacy of Enflurane can be increased when used in combination with Magnesium sulfate. |
| Pregabalin | The therapeutic efficacy of Pregabalin can be increased when used in combination with Magnesium sulfate. |
| Temazepam | The therapeutic efficacy of Temazepam can be increased when used in combination with Magnesium sulfate. |
| Reboxetine | The therapeutic efficacy of Reboxetine can be increased when used in combination with Magnesium sulfate. |
| Butabarbital | The therapeutic efficacy of Butabarbital can be increased when used in combination with Magnesium sulfate. |
| Butalbital | The therapeutic efficacy of Butalbital can be increased when used in combination with Magnesium sulfate. |
| Ziprasidone | The therapeutic efficacy of Ziprasidone can be increased when used in combination with Magnesium sulfate. |
| Methysergide | The therapeutic efficacy of Methysergide can be increased when used in combination with Magnesium sulfate. |
| Cabergoline | The therapeutic efficacy of Cabergoline can be increased when used in combination with Magnesium sulfate. |
| Phenytoin | The therapeutic efficacy of Phenytoin can be increased when used in combination with Magnesium sulfate. |
| Topiramate | The therapeutic efficacy of Topiramate can be increased when used in combination with Magnesium sulfate. |
| Clemastine | The therapeutic efficacy of Clemastine can be increased when used in combination with Magnesium sulfate. |
| Venlafaxine | The therapeutic efficacy of Venlafaxine can be increased when used in combination with Magnesium sulfate. |
| Etomidate | The therapeutic efficacy of Etomidate can be increased when used in combination with Magnesium sulfate. |
| Morphine | The therapeutic efficacy of Morphine can be increased when used in combination with Magnesium sulfate. |
| Talbutal | The therapeutic efficacy of Talbutal can be increased when used in combination with Magnesium sulfate. |
| Pentobarbital | The therapeutic efficacy of Pentobarbital can be increased when used in combination with Magnesium sulfate. |
| Valproic acid | The therapeutic efficacy of Valproic acid can be increased when used in combination with Magnesium sulfate. |
| Zolmitriptan | The therapeutic efficacy of Zolmitriptan can be increased when used in combination with Magnesium sulfate. |
| Codeine | The therapeutic efficacy of Codeine can be increased when used in combination with Magnesium sulfate. |
| Dihydroergotamine | The therapeutic efficacy of Dihydroergotamine can be increased when used in combination with Magnesium sulfate. |
| Amitriptyline | The therapeutic efficacy of Amitriptyline can be increased when used in combination with Magnesium sulfate. |
| Tolcapone | The therapeutic efficacy of Tolcapone can be increased when used in combination with Magnesium sulfate. |
| Hydromorphone | The therapeutic efficacy of Hydromorphone can be increased when used in combination with Magnesium sulfate. |
| Olanzapine | The therapeutic efficacy of Olanzapine can be increased when used in combination with Magnesium sulfate. |
| Cetirizine | The therapeutic efficacy of Cetirizine can be increased when used in combination with Magnesium sulfate. |
| Protriptyline | The therapeutic efficacy of Protriptyline can be increased when used in combination with Magnesium sulfate. |
| Trimethadione | The therapeutic efficacy of Trimethadione can be increased when used in combination with Magnesium sulfate. |
| Clobazam | The therapeutic efficacy of Clobazam can be increased when used in combination with Magnesium sulfate. |
| Chlorzoxazone | The therapeutic efficacy of Chlorzoxazone can be increased when used in combination with Magnesium sulfate. |
| Clozapine | The therapeutic efficacy of Clozapine can be increased when used in combination with Magnesium sulfate. |
| Mirtazapine | The therapeutic efficacy of Mirtazapine can be increased when used in combination with Magnesium sulfate. |
| Meprobamate | The therapeutic efficacy of Meprobamate can be increased when used in combination with Magnesium sulfate. |
| Thiethylperazine | The therapeutic efficacy of Thiethylperazine can be increased when used in combination with Magnesium sulfate. |
| Palonosetron | The therapeutic efficacy of Palonosetron can be increased when used in combination with Magnesium sulfate. |
| Sulpiride | The therapeutic efficacy of Sulpiride can be increased when used in combination with Magnesium sulfate. |
| Carisoprodol | The therapeutic efficacy of Carisoprodol can be increased when used in combination with Magnesium sulfate. |
| Eszopiclone | The therapeutic efficacy of Eszopiclone can be increased when used in combination with Magnesium sulfate. |
| Alprazolam | The therapeutic efficacy of Alprazolam can be increased when used in combination with Magnesium sulfate. |
| Dexbrompheniramine | The therapeutic efficacy of Dexbrompheniramine can be increased when used in combination with Magnesium sulfate. |
| Loxapine | The therapeutic efficacy of Loxapine can be increased when used in combination with Magnesium sulfate. |
| Remoxipride | The therapeutic efficacy of Remoxipride can be increased when used in combination with Magnesium sulfate. |
| Metocurine iodide | The therapeutic efficacy of Metocurine iodide can be increased when used in combination with Magnesium sulfate. |
| Secobarbital | The therapeutic efficacy of Secobarbital can be increased when used in combination with Magnesium sulfate. |
| Promazine | The therapeutic efficacy of Promazine can be increased when used in combination with Magnesium sulfate. |
| Methocarbamol | The therapeutic efficacy of Methocarbamol can be increased when used in combination with Magnesium sulfate. |
| Zolpidem | The therapeutic efficacy of Zolpidem can be increased when used in combination with Magnesium sulfate. |
| Triprolidine | The therapeutic efficacy of Triprolidine can be increased when used in combination with Magnesium sulfate. |
| Prochlorperazine | The therapeutic efficacy of Prochlorperazine can be increased when used in combination with Magnesium sulfate. |
| Cyproheptadine | The therapeutic efficacy of Cyproheptadine can be increased when used in combination with Magnesium sulfate. |
| Droperidol | The therapeutic efficacy of Droperidol can be increased when used in combination with Magnesium sulfate. |
| Meperidine | The therapeutic efficacy of Meperidine can be increased when used in combination with Magnesium sulfate. |
| Imipramine | The therapeutic efficacy of Imipramine can be increased when used in combination with Magnesium sulfate. |
| Metharbital | The therapeutic efficacy of Metharbital can be increased when used in combination with Magnesium sulfate. |
| Quinine | The therapeutic efficacy of Quinine can be increased when used in combination with Magnesium sulfate. |
| Dronabinol | The therapeutic efficacy of Dronabinol can be increased when used in combination with Magnesium sulfate. |
| Fluoxetine | The therapeutic efficacy of Fluoxetine can be increased when used in combination with Magnesium sulfate. |
| Methohexital | The therapeutic efficacy of Methohexital can be increased when used in combination with Magnesium sulfate. |
| Chlordiazepoxide | The therapeutic efficacy of Chlordiazepoxide can be increased when used in combination with Magnesium sulfate. |
| Duloxetine | The therapeutic efficacy of Duloxetine can be increased when used in combination with Magnesium sulfate. |
| Chlorpromazine | The therapeutic efficacy of Chlorpromazine can be increased when used in combination with Magnesium sulfate. |
| Gallamine triethiodide | The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium sulfate. |
| Nabilone | The therapeutic efficacy of Nabilone can be increased when used in combination with Magnesium sulfate. |
| Entacapone | The therapeutic efficacy of Entacapone can be increased when used in combination with Magnesium sulfate. |
| Oxycodone | The therapeutic efficacy of Oxycodone can be increased when used in combination with Magnesium sulfate. |
| Haloperidol | The therapeutic efficacy of Haloperidol can be increased when used in combination with Magnesium sulfate. |
| Triflupromazine | The therapeutic efficacy of Triflupromazine can be increased when used in combination with Magnesium sulfate. |
| Dextromethorphan | The therapeutic efficacy of Dextromethorphan can be increased when used in combination with Magnesium sulfate. |
| Mephenytoin | The therapeutic efficacy of Mephenytoin can be increased when used in combination with Magnesium sulfate. |
| Nortriptyline | The therapeutic efficacy of Nortriptyline can be increased when used in combination with Magnesium sulfate. |
| Amoxapine | The therapeutic efficacy of Amoxapine can be increased when used in combination with Magnesium sulfate. |
| Adinazolam | The therapeutic efficacy of Adinazolam can be increased when used in combination with Magnesium sulfate. |
| Lamotrigine | The therapeutic efficacy of Lamotrigine can be increased when used in combination with Magnesium sulfate. |
| Carbamazepine | The therapeutic efficacy of Carbamazepine can be increased when used in combination with Magnesium sulfate. |
| Cisatracurium | The therapeutic efficacy of Cisatracurium can be increased when used in combination with Magnesium sulfate. |
| Fenfluramine | The therapeutic efficacy of Fenfluramine can be increased when used in combination with Magnesium sulfate. |
| Mazindol | The therapeutic efficacy of Mazindol can be increased when used in combination with Magnesium sulfate. |
| Fluticasone propionate | The therapeutic efficacy of Fluticasone propionate can be increased when used in combination with Magnesium sulfate. |
| Lisuride | The therapeutic efficacy of Lisuride can be increased when used in combination with Magnesium sulfate. |
| Ethosuximide | The therapeutic efficacy of Ethosuximide can be increased when used in combination with Magnesium sulfate. |
| Thiopental | The therapeutic efficacy of Thiopental can be increased when used in combination with Magnesium sulfate. |
| Cisapride | The therapeutic efficacy of Cisapride can be increased when used in combination with Magnesium sulfate. |
| Butorphanol | The therapeutic efficacy of Butorphanol can be increased when used in combination with Magnesium sulfate. |