Fluphenazine

DB00623

small molecule approved

Deskripsi

A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.

Struktur Molekul 2D

Berat 437.522
Wujud liquid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

2 Data
  • 1. Avoid alcohol.
  • 2. Take with food. Food reduces irritation.

Interaksi Obat

957 Data
Buprenorphine Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Hydrocodone Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Magnesium sulfate The therapeutic efficacy of Fluphenazine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Mirtazapine Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Orphenadrine Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Rotigotine Fluphenazine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Fluphenazine.
Sodium oxybate Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Thalidomide Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Amisulpride Fluphenazine may increase the antipsychotic activities of Amisulpride.
Methylphenidate The risk or severity of adverse effects can be increased when Fluphenazine is combined with Methylphenidate.
Dexmethylphenidate The risk or severity of adverse effects can be increased when Fluphenazine is combined with Dexmethylphenidate.
Metoclopramide The risk or severity of adverse effects can be increased when Metoclopramide is combined with Fluphenazine.
Quinagolide The therapeutic efficacy of Quinagolide can be decreased when used in combination with Fluphenazine.
Sulpiride Fluphenazine may increase the antipsychotic activities of Sulpiride.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Fluphenazine.
Lithium citrate Lithium citrate may increase the neurotoxic activities of Fluphenazine.
Lithium hydroxide Lithium hydroxide may increase the neurotoxic activities of Fluphenazine.
Mequitazine Fluphenazine may increase the arrhythmogenic activities of Mequitazine.
Thiopental The risk or severity of adverse effects can be increased when Fluphenazine is combined with Thiopental.
Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Fluphenazine.
Metyrosine The risk or severity of extrapyramidal symptoms and CNS depression can be increased when Metyrosine is combined with Fluphenazine.
Ethanol Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Zimelidine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Dapoxetine.
Seproxetine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Seproxetine.
Fluvoxamine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Fluphenazine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Fluphenazine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Fluphenazine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Fluphenazine is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Fluphenazine is combined with Escitalopram.
Milnacipran The risk or severity of adverse effects can be increased when Fluphenazine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Desvenlafaxine.
Levomilnacipran The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Fluphenazine.
Indalpine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Fluphenazine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Fluphenazine is combined with Alaproclate.
Esmolol The serum concentration of Esmolol can be increased when it is combined with Fluphenazine.
Betaxolol The serum concentration of Betaxolol can be increased when it is combined with Fluphenazine.
Metoprolol The serum concentration of Metoprolol can be increased when it is combined with Fluphenazine.
Atenolol The serum concentration of Atenolol can be increased when it is combined with Fluphenazine.
Propranolol The serum concentration of Propranolol can be increased when it is combined with Fluphenazine.
Labetalol The serum concentration of Labetalol can be increased when it is combined with Fluphenazine.
Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Fluphenazine.
Alprenolol The serum concentration of Alprenolol can be increased when it is combined with Fluphenazine.
Pindolol The serum concentration of Pindolol can be increased when it is combined with Fluphenazine.
Carvedilol The serum concentration of Carvedilol can be increased when it is combined with Fluphenazine.
Propafenone The serum concentration of Propafenone can be increased when it is combined with Fluphenazine.
Acebutolol The serum concentration of Acebutolol can be increased when it is combined with Fluphenazine.
Nadolol The serum concentration of Nadolol can be increased when it is combined with Fluphenazine.
Bevantolol The serum concentration of Bevantolol can be increased when it is combined with Fluphenazine.
Practolol The serum concentration of Practolol can be increased when it is combined with Fluphenazine.
Penbutolol The serum concentration of Penbutolol can be increased when it is combined with Fluphenazine.
Oxprenolol The serum concentration of Oxprenolol can be increased when it is combined with Fluphenazine.
Dexpropranolol The serum concentration of Dexpropranolol can be increased when it is combined with Fluphenazine.
Celiprolol The serum concentration of Celiprolol can be increased when it is combined with Fluphenazine.
Nebivolol The serum concentration of Nebivolol can be increased when it is combined with Fluphenazine.
Bufuralol The serum concentration of Bufuralol can be increased when it is combined with Fluphenazine.
Bopindolol The serum concentration of Bopindolol can be increased when it is combined with Fluphenazine.
Bupranolol The serum concentration of Bupranolol can be increased when it is combined with Fluphenazine.
Indenolol The serum concentration of Indenolol can be increased when it is combined with Fluphenazine.
Arotinolol The serum concentration of Arotinolol can be increased when it is combined with Fluphenazine.
Levobetaxolol The serum concentration of Levobetaxolol can be increased when it is combined with Fluphenazine.
Talinolol The serum concentration of Talinolol can be increased when it is combined with Fluphenazine.
Anisodamine The serum concentration of Anisodamine can be increased when it is combined with Fluphenazine.
Bucindolol The serum concentration of Bucindolol can be increased when it is combined with Fluphenazine.
Esatenolol The serum concentration of Esatenolol can be increased when it is combined with Fluphenazine.
Cloranolol The serum concentration of Cloranolol can be increased when it is combined with Fluphenazine.
Mepindolol The serum concentration of Mepindolol can be increased when it is combined with Fluphenazine.
Epanolol The serum concentration of Epanolol can be increased when it is combined with Fluphenazine.
Tertatolol The serum concentration of Tertatolol can be increased when it is combined with Fluphenazine.
Landiolol The serum concentration of Landiolol can be increased when it is combined with Fluphenazine.
Morphine The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Morphine.
Codeine The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Codeine.
Hydromorphone The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Hydromorphone.
Oxycodone The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Oxycodone.
Butorphanol The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Butorphanol.
Dextropropoxyphene The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Dextropropoxyphene.
Pentazocine The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Pentazocine.
Naltrexone The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Naltrexone.
Sufentanil The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Sufentanil.
Alfentanil The risk or severity of hypotension and CNS depression can be increased when Fluphenazine is combined with Alfentanil.

Target Protein

5-hydroxytryptamine receptor 1B HTR1B
D(2) dopamine receptor DRD2
D(1A) dopamine receptor DRD1
Androgen receptor AR
5-hydroxytryptamine receptor 2A HTR2A
5-hydroxytryptamine receptor 2C HTR2C
Calmodulin CALM1

Referensi & Sumber

Synthesis reference: Ullyot, G.E.; U.S. Patent 3,058,979; October 16, 1962; assigned to Smith Kline & French Laboratories.

Contoh Produk & Brand

Produk: 238 • International brands: 14
Produk
  • Apo Fluphenazine Tab 2.5mg
    Tablet • 2.5 mg • Oral • Canada • Generic • Approved
  • Apo-fluphenazine Injectable
    Liquid • 25 mg / mL • Intramuscular; Subcutaneous • Canada • Generic • Approved
  • Fluphenazine
    Tablet • 1 mg • Oral • Canada • Approved
  • Fluphenazine
    Tablet • 5 mg • Oral • Canada • Approved
  • Fluphenazine
    Tablet • 2 mg • Oral • Canada • Approved
  • Fluphenazine 1 Tab 1mg
    Tablet • 1 mg • Oral • Canada • Approved
  • Fluphenazine 2 Tab 2mg
    Tablet • 2 mg • Oral • Canada • Approved
  • Fluphenazine 5 Tab 5mg
    Tablet • 5 mg • Oral • Canada • Approved
Menampilkan 8 dari 238 produk.
International Brands
  • Anatensol — Bristol-Myers Squibb
  • Dapotum D
  • Fludecasin — Tanabe Mitsubishi Pharma
  • Fludecate — Rafa
  • Flumezin — Tanabe Mitsubishi Pharma
  • Funazine — Johnson
  • Lyogen — Lundbeck
  • Lyogen Depot — Lundbeck
  • Lyogen Retard — Lundbeck
  • Metoten — Hemofarm

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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