Oral, rat: LD50 = 2372 mg/kg
A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Desmopressin | The therapeutic efficacy of Desmopressin can be decreased when used in combination with Demeclocycline. |
| Succinylcholine | The therapeutic efficacy of Succinylcholine can be increased when used in combination with Demeclocycline. |
| Metocurine iodide | The therapeutic efficacy of Metocurine iodide can be increased when used in combination with Demeclocycline. |
| Gallamine triethiodide | The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Demeclocycline. |
| Cisatracurium | Demeclocycline may increase the neuromuscular blocking activities of Cisatracurium. |
| Rocuronium | The therapeutic efficacy of Rocuronium can be increased when used in combination with Demeclocycline. |
| Atracurium besylate | The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Demeclocycline. |
| Doxacurium | The therapeutic efficacy of Doxacurium can be increased when used in combination with Demeclocycline. |
| Mivacurium | The therapeutic efficacy of Mivacurium can be increased when used in combination with Demeclocycline. |
| Decamethonium | The therapeutic efficacy of Decamethonium can be increased when used in combination with Demeclocycline. |
| Metocurine | The therapeutic efficacy of Metocurine can be increased when used in combination with Demeclocycline. |
| Pancuronium | The therapeutic efficacy of Pancuronium can be increased when used in combination with Demeclocycline. |
| Pipecuronium | The therapeutic efficacy of Pipecuronium can be increased when used in combination with Demeclocycline. |
| Vecuronium | The therapeutic efficacy of Vecuronium can be increased when used in combination with Demeclocycline. |
| Rapacuronium | The therapeutic efficacy of Rapacuronium can be increased when used in combination with Demeclocycline. |
| Pyrantel | The therapeutic efficacy of Pyrantel can be increased when used in combination with Demeclocycline. |
| Neosaxitoxin | The therapeutic efficacy of Neosaxitoxin can be increased when used in combination with Demeclocycline. |
| Atracurium | The therapeutic efficacy of Atracurium can be increased when used in combination with Demeclocycline. |
| Gallamine | The therapeutic efficacy of Gallamine can be increased when used in combination with Demeclocycline. |
| Alcuronium | The therapeutic efficacy of Alcuronium can be increased when used in combination with Demeclocycline. |
| Tubocurarine | The therapeutic efficacy of Tubocurarine can be increased when used in combination with Demeclocycline. |
| Bismuth subsalicylate | The serum concentration of Demeclocycline can be decreased when it is combined with Bismuth subsalicylate. |
| Mecamylamine | Demeclocycline may increase the neuromuscular blocking activities of Mecamylamine. |
| Mipomersen | Demeclocycline may increase the hepatotoxic activities of Mipomersen. |
| Quinapril | Quinapril can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Sucralfate | Sucralfate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Iron sucrose | The serum concentration of Demeclocycline can be decreased when it is combined with Iron sucrose. |
| Flucloxacillin | The therapeutic efficacy of Flucloxacillin can be decreased when used in combination with Demeclocycline. |
| Piperacillin | The therapeutic efficacy of Piperacillin can be decreased when used in combination with Demeclocycline. |
| Ampicillin | The therapeutic efficacy of Ampicillin can be decreased when used in combination with Demeclocycline. |
| Phenoxymethylpenicillin | The therapeutic efficacy of Phenoxymethylpenicillin can be decreased when used in combination with Demeclocycline. |
| Dicloxacillin | The therapeutic efficacy of Dicloxacillin can be decreased when used in combination with Demeclocycline. |
| Carbenicillin | The therapeutic efficacy of Carbenicillin can be decreased when used in combination with Demeclocycline. |
| Nafcillin | The therapeutic efficacy of Nafcillin can be decreased when used in combination with Demeclocycline. |
| Oxacillin | The therapeutic efficacy of Oxacillin can be decreased when used in combination with Demeclocycline. |
| Hetacillin | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Demeclocycline. |
| Benzylpenicilloyl polylysine | The therapeutic efficacy of Benzylpenicilloyl polylysine can be decreased when used in combination with Demeclocycline. |
| Mezlocillin | The therapeutic efficacy of Mezlocillin can be decreased when used in combination with Demeclocycline. |
| Cyclacillin | The therapeutic efficacy of Cyclacillin can be decreased when used in combination with Demeclocycline. |
| Benzylpenicillin | The therapeutic efficacy of Benzylpenicillin can be decreased when used in combination with Demeclocycline. |
| Amoxicillin | The therapeutic efficacy of Amoxicillin can be decreased when used in combination with Demeclocycline. |
| Azlocillin | The therapeutic efficacy of Azlocillin can be decreased when used in combination with Demeclocycline. |
| Cloxacillin | The therapeutic efficacy of Cloxacillin can be decreased when used in combination with Demeclocycline. |
| Amdinocillin | The therapeutic efficacy of Amdinocillin can be decreased when used in combination with Demeclocycline. |
| Bacampicillin | The therapeutic efficacy of Bacampicillin can be decreased when used in combination with Demeclocycline. |
| Meticillin | The therapeutic efficacy of Meticillin can be decreased when used in combination with Demeclocycline. |
| Pivampicillin | The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Demeclocycline. |
| Pivmecillinam | The therapeutic efficacy of Pivmecillinam can be decreased when used in combination with Demeclocycline. |
| Ticarcillin | The therapeutic efficacy of Ticarcillin can be decreased when used in combination with Demeclocycline. |
| Azidocillin | The therapeutic efficacy of Azidocillin can be decreased when used in combination with Demeclocycline. |
| Carindacillin | The therapeutic efficacy of Carindacillin can be decreased when used in combination with Demeclocycline. |
| Procaine benzylpenicillin | The therapeutic efficacy of Procaine benzylpenicillin can be decreased when used in combination with Demeclocycline. |
| Sultamicillin | The therapeutic efficacy of Sultamicillin can be decreased when used in combination with Demeclocycline. |
| Temocillin | The therapeutic efficacy of Temocillin can be decreased when used in combination with Demeclocycline. |
| Epicillin | The therapeutic efficacy of Epicillin can be decreased when used in combination with Demeclocycline. |
| Pheneticillin | The therapeutic efficacy of Pheneticillin can be decreased when used in combination with Demeclocycline. |
| Carfecillin | The therapeutic efficacy of Carfecillin can be decreased when used in combination with Demeclocycline. |
| Propicillin | The therapeutic efficacy of Propicillin can be decreased when used in combination with Demeclocycline. |
| Clometocillin | The therapeutic efficacy of Clometocillin can be decreased when used in combination with Demeclocycline. |
| Sulbenicillin | The therapeutic efficacy of Sulbenicillin can be decreased when used in combination with Demeclocycline. |
| Penamecillin | The therapeutic efficacy of Penamecillin can be decreased when used in combination with Demeclocycline. |
| Talampicillin | The therapeutic efficacy of Talampicillin can be decreased when used in combination with Demeclocycline. |
| Aspoxicillin | The therapeutic efficacy of Aspoxicillin can be decreased when used in combination with Demeclocycline. |
| Metampicillin | The therapeutic efficacy of Metampicillin can be decreased when used in combination with Demeclocycline. |
| Picosulfuric acid | The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Demeclocycline. |
| Bismuth subcitrate potassium | The serum concentration of Demeclocycline can be decreased when it is combined with Bismuth subcitrate potassium. |
| Strontium ranelate | The serum concentration of Demeclocycline can be decreased when it is combined with Strontium ranelate. |
| Calcium glucoheptonate | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium glucoheptonate. |
| Calcium glubionate anhydrous | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium glubionate anhydrous. |
| Calcium gluconate | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium gluconate. |
| Calcium citrate | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium citrate. |
| Calcium Phosphate | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium Phosphate. |
| Calcium lactate | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium lactate. |
| Calcium lactate gluconate | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium lactate gluconate. |
| Calcium pangamate | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium pangamate. |
| Calcium levulinate | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium levulinate. |
| Calcium acetate | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium acetate. |
| Calcium chloride | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium chloride. |
| Calcium | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium. |
| Calcium cation | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium cation. |
| Calcium polycarbophil | The serum concentration of Demeclocycline can be decreased when it is combined with Calcium polycarbophil. |
| Colestipol | Colestipol can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Colesevelam | Colesevelam can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Cholestyramine | Cholestyramine can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Sevelamer | Sevelamer can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium sulfate | Magnesium sulfate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium salicylate | Magnesium salicylate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium chloride | Magnesium chloride can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium citrate | Magnesium citrate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium aspartate | Magnesium aspartate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium gluconate | Magnesium gluconate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium orotate | Magnesium orotate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium levulinate | Magnesium levulinate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium lactate | Magnesium lactate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Calcium carbonate | Calcium carbonate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium oxide | Magnesium oxide can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magaldrate | Magaldrate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium hydroxide | Magnesium hydroxide can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium trisilicate | Magnesium trisilicate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium carbonate | Magnesium carbonate can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |