Candoxatril

DB00616

small molecule experimental

Deskripsi

Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.

Struktur Molekul 2D

Berat 515.6383
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

627 Data
Alfuzosin Alfuzosin may increase the hypotensive activities of Candoxatril.
Amifostine Candoxatril may increase the hypotensive activities of Amifostine.
Diazoxide Diazoxide may increase the hypotensive activities of Candoxatril.
Methylphenidate Methylphenidate may decrease the antihypertensive activities of Candoxatril.
Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Candoxatril.
Obinutuzumab Candoxatril may increase the hypotensive activities of Obinutuzumab.
Pentoxifylline Pentoxifylline may increase the hypotensive activities of Candoxatril.
Rituximab Candoxatril may increase the hypotensive activities of Rituximab.
Desmopressin Desmopressin may decrease the antihypertensive activities of Candoxatril.
Cyclosporine Cyclosporine may decrease the antihypertensive activities of Candoxatril.
Phentermine Phentermine may decrease the antihypertensive activities of Candoxatril.
Midodrine Midodrine may decrease the antihypertensive activities of Candoxatril.
Eletriptan Eletriptan may decrease the antihypertensive activities of Candoxatril.
Isoetharine Isoetharine may decrease the antihypertensive activities of Candoxatril.
Methysergide Methysergide may decrease the antihypertensive activities of Candoxatril.
Cabergoline Cabergoline may decrease the antihypertensive activities of Candoxatril.
Atomoxetine Atomoxetine may decrease the antihypertensive activities of Candoxatril.
Etomidate Etomidate may decrease the antihypertensive activities of Candoxatril.
Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Candoxatril.
Dihydroergotamine Dihydroergotamine may decrease the antihypertensive activities of Candoxatril.
Amitriptyline Amitriptyline may decrease the antihypertensive activities of Candoxatril.
Protriptyline Protriptyline may decrease the antihypertensive activities of Candoxatril.
Methylergometrine Methylergometrine may decrease the antihypertensive activities of Candoxatril.
Norepinephrine Norepinephrine may decrease the antihypertensive activities of Candoxatril.
Mirtazapine Mirtazapine may decrease the antihypertensive activities of Candoxatril.
Phenylephrine Phenylephrine may decrease the antihypertensive activities of Candoxatril.
Phenylpropanolamine Phenylpropanolamine may decrease the antihypertensive activities of Candoxatril.
Promazine Promazine may decrease the antihypertensive activities of Candoxatril.
Droperidol Droperidol may decrease the antihypertensive activities of Candoxatril.
Buspirone Buspirone may decrease the antihypertensive activities of Candoxatril.
Nortriptyline Nortriptyline may decrease the antihypertensive activities of Candoxatril.
Amoxapine Amoxapine may decrease the antihypertensive activities of Candoxatril.
Doxapram Doxapram may decrease the antihypertensive activities of Candoxatril.
Atropine Atropine may decrease the antihypertensive activities of Candoxatril.
Lisuride Lisuride may decrease the antihypertensive activities of Candoxatril.
Metaraminol Metaraminol may decrease the antihypertensive activities of Candoxatril.
Trazodone Trazodone may decrease the antihypertensive activities of Candoxatril.
Epinephrine Epinephrine may decrease the antihypertensive activities of Candoxatril.
Sumatriptan Sumatriptan may decrease the antihypertensive activities of Candoxatril.
Ergotamine Ergotamine may decrease the antihypertensive activities of Candoxatril.
Nicergoline Nicergoline may decrease the antihypertensive activities of Candoxatril.
Methoxamine Methoxamine may decrease the antihypertensive activities of Candoxatril.
Trimipramine Trimipramine may decrease the antihypertensive activities of Candoxatril.
Risperidone Risperidone may decrease the antihypertensive activities of Candoxatril.
Propiomazine Propiomazine may decrease the antihypertensive activities of Candoxatril.
Alfentanil Alfentanil may decrease the antihypertensive activities of Candoxatril.
Fentanyl Fentanyl may decrease the antihypertensive activities of Candoxatril.
Orciprenaline Orciprenaline may decrease the antihypertensive activities of Candoxatril.
Phenmetrazine Phenmetrazine may decrease the antihypertensive activities of Candoxatril.
Trifluoperazine Trifluoperazine may decrease the antihypertensive activities of Candoxatril.
Dobutamine Dobutamine may decrease the antihypertensive activities of Candoxatril.
Pseudoephedrine Pseudoephedrine may decrease the antihypertensive activities of Candoxatril.
Benzphetamine Benzphetamine may decrease the antihypertensive activities of Candoxatril.
Ritodrine Ritodrine may decrease the antihypertensive activities of Candoxatril.
Terbutaline Terbutaline may decrease the antihypertensive activities of Candoxatril.
Flupentixol Flupentixol may decrease the antihypertensive activities of Candoxatril.
Bitolterol Bitolterol may decrease the antihypertensive activities of Candoxatril.
Quinidine Quinidine may decrease the antihypertensive activities of Candoxatril.
Almotriptan Almotriptan may decrease the antihypertensive activities of Candoxatril.
Diethylpropion Diethylpropion may decrease the antihypertensive activities of Candoxatril.
Salmeterol Salmeterol may decrease the antihypertensive activities of Candoxatril.
Naratriptan Naratriptan may decrease the antihypertensive activities of Candoxatril.
Rizatriptan Rizatriptan may decrease the antihypertensive activities of Candoxatril.
Formoterol Formoterol may decrease the antihypertensive activities of Candoxatril.
Dopamine Dopamine may decrease the antihypertensive activities of Candoxatril.
Frovatriptan Frovatriptan may decrease the antihypertensive activities of Candoxatril.
Albuterol Salbutamol may decrease the antihypertensive activities of Candoxatril.
Methoxyflurane Methoxyflurane may decrease the antihypertensive activities of Candoxatril.
Ergoloid mesylate Ergoloid mesylate may decrease the antihypertensive activities of Candoxatril.
Isoprenaline Isoprenaline may decrease the antihypertensive activities of Candoxatril.
Arbutamine Arbutamine may decrease the antihypertensive activities of Candoxatril.
Dutasteride Dutasteride may decrease the antihypertensive activities of Candoxatril.
Doxepin Doxepin may decrease the antihypertensive activities of Candoxatril.
Nefazodone Nefazodone may decrease the antihypertensive activities of Candoxatril.
Desipramine Desipramine may decrease the antihypertensive activities of Candoxatril.
Propafenone Propafenone may decrease the antihypertensive activities of Candoxatril.
Pergolide Pergolide may decrease the antihypertensive activities of Candoxatril.
Finasteride Finasteride may decrease the antihypertensive activities of Candoxatril.
Ergometrine Ergometrine may decrease the antihypertensive activities of Candoxatril.
Lisdexamfetamine Lisdexamfetamine may decrease the antihypertensive activities of Candoxatril.
Paliperidone Paliperidone may decrease the antihypertensive activities of Candoxatril.
Arformoterol Arformoterol may decrease the antihypertensive activities of Candoxatril.
Fenoterol Fenoterol may decrease the antihypertensive activities of Candoxatril.
Pirbuterol Pirbuterol may decrease the antihypertensive activities of Candoxatril.
Ephedra sinica root Ephedra sinica root may decrease the antihypertensive activities of Candoxatril.
Ephedrine Ephedrine may decrease the antihypertensive activities of Candoxatril.
Mephentermine Mephentermine may decrease the antihypertensive activities of Candoxatril.
Procaterol Procaterol may decrease the antihypertensive activities of Candoxatril.
Yohimbine Yohimbine may decrease the antihypertensive activities of Candoxatril.
Methotrimeprazine Methotrimeprazine may decrease the antihypertensive activities of Candoxatril.
Clenbuterol Clenbuterol may decrease the antihypertensive activities of Candoxatril.
Bambuterol Bambuterol may decrease the antihypertensive activities of Candoxatril.
MMDA MMDA may decrease the antihypertensive activities of Candoxatril.
Midomafetamine Midomafetamine may decrease the antihypertensive activities of Candoxatril.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Candoxatril.
4-Methoxyamphetamine 4-Methoxyamphetamine may decrease the antihypertensive activities of Candoxatril.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Candoxatril.
Tenamfetamine Tenamfetamine may decrease the antihypertensive activities of Candoxatril.
Chlorphentermine Chlorphentermine may decrease the antihypertensive activities of Candoxatril.
Dextroamphetamine Dextroamphetamine may decrease the antihypertensive activities of Candoxatril.

Target Protein

Neprilysin MME
Angiotensin-converting enzyme ACE

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 0
Belum ada data produk/brand untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field produk/brand.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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