Peringatan Keamanan

Adverse effects may include stomach or bowel upsets and rarely allergic reactions. Very rarely severe headache and vision problems may be signs of dangerous intracranial hypertenion.

Oxytetracycline

DB00595

small molecule approved investigational vet_approved

Deskripsi

A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.

Struktur Molekul 2D

Berat 460.434
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Readily absorbed following oral administration.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

2 Data
  • 1. Avoid milk and dairy products. Take at least 1 hour before or two hours after consuming dairy products.
  • 2. Take separate from meals. Take at least one hour before or two hours after a meal.

Interaksi Obat

475 Data
Succinylcholine The therapeutic efficacy of Succinylcholine can be increased when used in combination with Oxytetracycline.
Metocurine iodide The therapeutic efficacy of Metocurine iodide can be increased when used in combination with Oxytetracycline.
Gallamine triethiodide The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Oxytetracycline.
Cisatracurium Oxytetracycline may increase the neuromuscular blocking activities of Cisatracurium.
Rocuronium The therapeutic efficacy of Rocuronium can be increased when used in combination with Oxytetracycline.
Atracurium besylate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Oxytetracycline.
Doxacurium The therapeutic efficacy of Doxacurium can be increased when used in combination with Oxytetracycline.
Mivacurium The therapeutic efficacy of Mivacurium can be increased when used in combination with Oxytetracycline.
Decamethonium The therapeutic efficacy of Decamethonium can be increased when used in combination with Oxytetracycline.
Metocurine The therapeutic efficacy of Metocurine can be increased when used in combination with Oxytetracycline.
Pancuronium The therapeutic efficacy of Pancuronium can be increased when used in combination with Oxytetracycline.
Pipecuronium The therapeutic efficacy of Pipecuronium can be increased when used in combination with Oxytetracycline.
Vecuronium The therapeutic efficacy of Vecuronium can be increased when used in combination with Oxytetracycline.
Rapacuronium The therapeutic efficacy of Rapacuronium can be increased when used in combination with Oxytetracycline.
Pyrantel The therapeutic efficacy of Pyrantel can be increased when used in combination with Oxytetracycline.
Neosaxitoxin The therapeutic efficacy of Neosaxitoxin can be increased when used in combination with Oxytetracycline.
Atracurium The therapeutic efficacy of Atracurium can be increased when used in combination with Oxytetracycline.
Gallamine The therapeutic efficacy of Gallamine can be increased when used in combination with Oxytetracycline.
Alcuronium The therapeutic efficacy of Alcuronium can be increased when used in combination with Oxytetracycline.
Tubocurarine The therapeutic efficacy of Tubocurarine can be increased when used in combination with Oxytetracycline.
Bismuth subsalicylate The serum concentration of Oxytetracycline can be decreased when it is combined with Bismuth subsalicylate.
Mecamylamine Oxytetracycline may increase the neuromuscular blocking activities of Mecamylamine.
Mipomersen Oxytetracycline may increase the hepatotoxic activities of Mipomersen.
Quinapril Quinapril can cause a decrease in the absorption of Oxytetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sucralfate Sucralfate can cause a decrease in the absorption of Oxytetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron sucrose The serum concentration of Oxytetracycline can be decreased when it is combined with Iron sucrose.
Flucloxacillin The therapeutic efficacy of Flucloxacillin can be decreased when used in combination with Oxytetracycline.
Piperacillin The therapeutic efficacy of Piperacillin can be decreased when used in combination with Oxytetracycline.
Ampicillin The therapeutic efficacy of Ampicillin can be decreased when used in combination with Oxytetracycline.
Phenoxymethylpenicillin The therapeutic efficacy of Phenoxymethylpenicillin can be decreased when used in combination with Oxytetracycline.
Dicloxacillin The therapeutic efficacy of Dicloxacillin can be decreased when used in combination with Oxytetracycline.
Carbenicillin The therapeutic efficacy of Carbenicillin can be decreased when used in combination with Oxytetracycline.
Nafcillin The therapeutic efficacy of Nafcillin can be decreased when used in combination with Oxytetracycline.
Oxacillin The therapeutic efficacy of Oxacillin can be decreased when used in combination with Oxytetracycline.
Hetacillin The therapeutic efficacy of Hetacillin can be decreased when used in combination with Oxytetracycline.
Benzylpenicilloyl polylysine The therapeutic efficacy of Benzylpenicilloyl polylysine can be decreased when used in combination with Oxytetracycline.
Mezlocillin The therapeutic efficacy of Mezlocillin can be decreased when used in combination with Oxytetracycline.
Cyclacillin The therapeutic efficacy of Cyclacillin can be decreased when used in combination with Oxytetracycline.
Benzylpenicillin The therapeutic efficacy of Benzylpenicillin can be decreased when used in combination with Oxytetracycline.
Amoxicillin The therapeutic efficacy of Amoxicillin can be decreased when used in combination with Oxytetracycline.
Azlocillin The therapeutic efficacy of Azlocillin can be decreased when used in combination with Oxytetracycline.
Cloxacillin The therapeutic efficacy of Cloxacillin can be decreased when used in combination with Oxytetracycline.
Amdinocillin The therapeutic efficacy of Amdinocillin can be decreased when used in combination with Oxytetracycline.
Bacampicillin The therapeutic efficacy of Bacampicillin can be decreased when used in combination with Oxytetracycline.
Meticillin The therapeutic efficacy of Meticillin can be decreased when used in combination with Oxytetracycline.
Pivampicillin The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Oxytetracycline.
Pivmecillinam The therapeutic efficacy of Pivmecillinam can be decreased when used in combination with Oxytetracycline.
Ticarcillin The therapeutic efficacy of Ticarcillin can be decreased when used in combination with Oxytetracycline.
Azidocillin The therapeutic efficacy of Azidocillin can be decreased when used in combination with Oxytetracycline.
Carindacillin The therapeutic efficacy of Carindacillin can be decreased when used in combination with Oxytetracycline.
Procaine benzylpenicillin The therapeutic efficacy of Procaine benzylpenicillin can be decreased when used in combination with Oxytetracycline.
Sultamicillin The therapeutic efficacy of Sultamicillin can be decreased when used in combination with Oxytetracycline.
Temocillin The therapeutic efficacy of Temocillin can be decreased when used in combination with Oxytetracycline.
Epicillin The therapeutic efficacy of Epicillin can be decreased when used in combination with Oxytetracycline.
Pheneticillin The therapeutic efficacy of Pheneticillin can be decreased when used in combination with Oxytetracycline.
Carfecillin The therapeutic efficacy of Carfecillin can be decreased when used in combination with Oxytetracycline.
Propicillin The therapeutic efficacy of Propicillin can be decreased when used in combination with Oxytetracycline.
Clometocillin The therapeutic efficacy of Clometocillin can be decreased when used in combination with Oxytetracycline.
Sulbenicillin The therapeutic efficacy of Sulbenicillin can be decreased when used in combination with Oxytetracycline.
Penamecillin The therapeutic efficacy of Penamecillin can be decreased when used in combination with Oxytetracycline.
Talampicillin The therapeutic efficacy of Talampicillin can be decreased when used in combination with Oxytetracycline.
Aspoxicillin The therapeutic efficacy of Aspoxicillin can be decreased when used in combination with Oxytetracycline.
Metampicillin The therapeutic efficacy of Metampicillin can be decreased when used in combination with Oxytetracycline.
Succinic acid The excretion of Succinic acid can be decreased when combined with Oxytetracycline.
Citrulline The excretion of Citrulline can be decreased when combined with Oxytetracycline.
Pravastatin The excretion of Oxytetracycline can be decreased when combined with Pravastatin.
Oseltamivir The excretion of Oseltamivir can be decreased when combined with Oxytetracycline.
Cefotiam The excretion of Oxytetracycline can be decreased when combined with Cefotiam.
Conjugated estrogens The excretion of Oxytetracycline can be decreased when combined with Conjugated estrogens.
Tenofovir disoproxil The excretion of Tenofovir disoproxil can be decreased when combined with Oxytetracycline.
Indomethacin The excretion of Oxytetracycline can be decreased when combined with Indomethacin.
Aminohippuric acid The excretion of Oxytetracycline can be decreased when combined with Aminohippuric acid.
Trifluridine The excretion of Trifluridine can be decreased when combined with Oxytetracycline.
Allopurinol The excretion of Allopurinol can be decreased when combined with Oxytetracycline.
Zidovudine The excretion of Oxytetracycline can be decreased when combined with Zidovudine.
Cimetidine The excretion of Oxytetracycline can be decreased when combined with Cimetidine.
Cefdinir The excretion of Cefdinir can be decreased when combined with Oxytetracycline.
Cephalexin The excretion of Oxytetracycline can be decreased when combined with Cephalexin.
Valaciclovir The excretion of Valaciclovir can be decreased when combined with Oxytetracycline.
Levocarnitine The excretion of Levocarnitine can be decreased when combined with Oxytetracycline.
Leucovorin The excretion of Leucovorin can be decreased when combined with Oxytetracycline.
Fluorescein The excretion of Fluorescein can be decreased when combined with Oxytetracycline.
Hydrocortisone The excretion of Hydrocortisone can be decreased when combined with Oxytetracycline.
Tetracycline The excretion of Tetracycline can be decreased when combined with Oxytetracycline.
Estradiol The excretion of Estradiol can be decreased when combined with Oxytetracycline.
Acyclovir The excretion of Acyclovir can be decreased when combined with Oxytetracycline.
Cefaclor The excretion of Cefaclor can be decreased when combined with Oxytetracycline.
Ranitidine The excretion of Ranitidine can be decreased when combined with Oxytetracycline.
Bumetanide The excretion of Bumetanide can be decreased when combined with Oxytetracycline.
Dinoprostone The excretion of Dinoprostone can be decreased when combined with Oxytetracycline.
Famotidine The excretion of Famotidine can be decreased when combined with Oxytetracycline.
Fexofenadine The excretion of Fexofenadine can be decreased when combined with Oxytetracycline.
Rosuvastatin The excretion of Rosuvastatin can be decreased when combined with Oxytetracycline.
Captopril The excretion of Captopril can be decreased when combined with Oxytetracycline.
Sitagliptin The excretion of Sitagliptin can be decreased when combined with Oxytetracycline.
Cefazolin The excretion of Cefazolin can be decreased when combined with Oxytetracycline.
Ceftizoxime The excretion of Ceftizoxime can be decreased when combined with Oxytetracycline.
Cefacetrile The excretion of Cefacetrile can be decreased when combined with Oxytetracycline.
Ceftibuten The excretion of Ceftibuten can be decreased when combined with Oxytetracycline.
Tazobactam The excretion of Tazobactam can be decreased when combined with Oxytetracycline.

Target Protein

30S ribosomal protein S9 rpsI
30S ribosomal protein S4 rpsD
16S ribosomal RNA

Referensi & Sumber

Synthesis reference: Janos Balint, Laszlo Cseke, Ferenc Fabian, Lajos Kun, Miklos Szarvas, "Process for the preparation of an oxytetracycline-calcium silicate complex salt from fermentation broth." U.S. Patent US4584135, issued April, 1951.
Artikel (PubMed)
  • PMID: 16816396
    Agwuh KN, MacGowan A: Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines. J Antimicrob Chemother. 2006 Aug;58(2):256-65. Epub 2006 Jul 1.

Contoh Produk & Brand

Produk: 4 • International brands: 9
Produk
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    Capsule • 250 mg/1 • Oral • US • Approved
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    Ointment • - • Ophthalmic • US • Generic • Approved
  • Urobiotic
    Capsule • - • Oral • US • Approved
International Brands
  • Adamycin — Teva
  • Anglocycline — Anglopak
  • Corsamycin — Corsa Industries
  • Oxacin — Doctor's Chemical Works
  • Oxypan — Adcock Ingram Pharmaceuticals
  • Oxyterracyna — Chema
  • Terrados — Pfizer
  • Tetran — Wagner Pharmafax
  • Tetrasona — Medifarma

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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