Sulfamethizole

DB00576

small molecule approved investigational vet_approved

Deskripsi

A sulfathiazole antibacterial agent.

Struktur Molekul 2D

Berat 270.331
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 3-8 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Rapidly absorbed.

Metabolisme

Hepatic.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Take separate from meals. Take Urobiotic at least 1 hour before or 2 hours after eating.

Interaksi Obat

307 Data
Nicotine The risk or severity of adverse effects can be increased when Sulfamethizole is combined with Nicotine.
Mecamylamine The risk or severity of adverse effects can be increased when Sulfamethizole is combined with Mecamylamine.
Pentolinium The risk or severity of adverse effects can be increased when Sulfamethizole is combined with Pentolinium.
Trimethaphan The risk or severity of adverse effects can be increased when Sulfamethizole is combined with Trimethaphan.
Hexamethonium The risk or severity of adverse effects can be increased when Sulfamethizole is combined with Hexamethonium.
Cyclopentamine The risk or severity of adverse effects can be increased when Sulfamethizole is combined with Cyclopentamine.
Methotrexate The protein binding of Methotrexate can be increased when combined with Sulfamethizole.
Dexketoprofen The risk or severity of adverse effects can be increased when Dexketoprofen is combined with Sulfamethizole.
Ketoprofen The risk or severity of adverse effects can be increased when Ketoprofen is combined with Sulfamethizole.
Cyclosporine The risk or severity of renal failure can be increased when Sulfamethizole is combined with Cyclosporine.
Insulin human The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin human.
Insulin lispro The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin lispro.
Insulin glargine The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin glargine.
Insulin pork The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin pork.
Troglitazone The metabolism of Troglitazone can be decreased when combined with Sulfamethizole.
Glimepiride The metabolism of Glimepiride can be decreased when combined with Sulfamethizole.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Sulfamethizole.
Disopyramide The therapeutic efficacy of Disopyramide can be increased when used in combination with Sulfamethizole.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Sulfamethizole.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Sulfamethizole.
Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Sulfamethizole.
Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Sulfamethizole.
Acetohexamide The metabolism of Acetohexamide can be decreased when combined with Sulfamethizole.
Quinine The metabolism of Quinine can be decreased when combined with Sulfamethizole.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Sulfamethizole.
Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Sulfamethizole.
Nateglinide The metabolism of Nateglinide can be decreased when combined with Sulfamethizole.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Sulfamethizole.
Mifepristone The therapeutic efficacy of Mifepristone can be increased when used in combination with Sulfamethizole.
Tolazamide The metabolism of Tolazamide can be decreased when combined with Sulfamethizole.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Sulfamethizole.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Sulfamethizole.
Sulfamethoxazole The metabolism of Sulfamethoxazole can be decreased when combined with Sulfamethizole.
Glyburide The metabolism of Glyburide can be decreased when combined with Sulfamethizole.
Glipizide The metabolism of Glipizide can be decreased when combined with Sulfamethizole.
Gliclazide The metabolism of Gliclazide can be decreased when combined with Sulfamethizole.
Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Sulfamethizole.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Sulfamethizole.
Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Sulfamethizole.
Gliquidone The metabolism of Gliquidone can be decreased when combined with Sulfamethizole.
Mitiglinide The therapeutic efficacy of Mitiglinide can be increased when used in combination with Sulfamethizole.
Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Sulfamethizole.
Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Sulfamethizole.
Exenatide The therapeutic efficacy of Exenatide can be increased when used in combination with Sulfamethizole.
Mecasermin The therapeutic efficacy of Mecasermin can be increased when used in combination with Sulfamethizole.
Pramlintide The therapeutic efficacy of Pramlintide can be increased when used in combination with Sulfamethizole.
Glisoxepide The metabolism of Glisoxepide can be decreased when combined with Sulfamethizole.
Insulin aspart The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin aspart.
Insulin detemir The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin detemir.
Insulin glulisine The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin glulisine.
Glymidine The therapeutic efficacy of Glymidine can be increased when used in combination with Sulfamethizole.
AICA ribonucleotide The therapeutic efficacy of AICA ribonucleotide can be increased when used in combination with Sulfamethizole.
Buformin The therapeutic efficacy of Buformin can be increased when used in combination with Sulfamethizole.
Vildagliptin The therapeutic efficacy of Vildagliptin can be increased when used in combination with Sulfamethizole.
Voglibose The therapeutic efficacy of Voglibose can be increased when used in combination with Sulfamethizole.
NN344 The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with NN344.
AMG-222 The therapeutic efficacy of AMG-222 can be increased when used in combination with Sulfamethizole.
Bisegliptin The therapeutic efficacy of Bisegliptin can be increased when used in combination with Sulfamethizole.
Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfamethizole.
Dapagliflozin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Sulfamethizole.
Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Sulfamethizole.
Liraglutide The therapeutic efficacy of Liraglutide can be increased when used in combination with Sulfamethizole.
Gosogliptin The therapeutic efficacy of Gosogliptin can be increased when used in combination with Sulfamethizole.
Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Sulfamethizole.
Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Sulfamethizole.
Glibornuride The metabolism of Glibornuride can be decreased when combined with Sulfamethizole.
Benfluorex The therapeutic efficacy of Benfluorex can be increased when used in combination with Sulfamethizole.
Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Sulfamethizole.
Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfamethizole.
Dulaglutide The therapeutic efficacy of Dulaglutide can be increased when used in combination with Sulfamethizole.
Lobeglitazone The therapeutic efficacy of Lobeglitazone can be increased when used in combination with Sulfamethizole.
Netoglitazone The therapeutic efficacy of Netoglitazone can be increased when used in combination with Sulfamethizole.
Rivoglitazone The therapeutic efficacy of Rivoglitazone can be increased when used in combination with Sulfamethizole.
Ciglitazone The therapeutic efficacy of Ciglitazone can be increased when used in combination with Sulfamethizole.
Lixisenatide The therapeutic efficacy of Lixisenatide can be increased when used in combination with Sulfamethizole.
Insulin beef The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin beef.
Insulin degludec The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin degludec.
Insulin peglispro The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin peglispro.
Insulin tregopil The risk or severity of hypoglycemia can be increased when Sulfamethizole is combined with Insulin tregopil.
Ipragliflozin The therapeutic efficacy of Ipragliflozin can be increased when used in combination with Sulfamethizole.
Dutogliptin The therapeutic efficacy of Dutogliptin can be increased when used in combination with Sulfamethizole.
Allicin The therapeutic efficacy of Allicin can be increased when used in combination with Sulfamethizole.
Tofogliflozin The therapeutic efficacy of Tofogliflozin can be increased when used in combination with Sulfamethizole.
Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Sulfamethizole.
2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Sulfamethizole.
Teneligliptin The therapeutic efficacy of Teneligliptin can be increased when used in combination with Sulfamethizole.
Omarigliptin The therapeutic efficacy of Omarigliptin can be increased when used in combination with Sulfamethizole.
Carmegliptin The therapeutic efficacy of Carmegliptin can be increased when used in combination with Sulfamethizole.
Gemigliptin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Sulfamethizole.
Anagliptin The therapeutic efficacy of Anagliptin can be increased when used in combination with Sulfamethizole.
Evogliptin The therapeutic efficacy of Evogliptin can be increased when used in combination with Sulfamethizole.
Sotagliflozin The therapeutic efficacy of Sotagliflozin can be increased when used in combination with Sulfamethizole.
Balaglitazone The therapeutic efficacy of Balaglitazone can be increased when used in combination with Sulfamethizole.
Remogliflozin etabonate The therapeutic efficacy of Remogliflozin etabonate can be increased when used in combination with Sulfamethizole.
Carbutamide The metabolism of Carbutamide can be decreased when combined with Sulfamethizole.
Guar gum The therapeutic efficacy of Guar gum can be increased when used in combination with Sulfamethizole.
Metahexamide The metabolism of Metahexamide can be decreased when combined with Sulfamethizole.
Semaglutide The therapeutic efficacy of Semaglutide can be increased when used in combination with Sulfamethizole.
Taspoglutide The therapeutic efficacy of Taspoglutide can be increased when used in combination with Sulfamethizole.
Englitazone The therapeutic efficacy of Englitazone can be increased when used in combination with Sulfamethizole.

Target Protein

Dihydropteroate synthase folP

Referensi & Sumber

Artikel (PubMed)
  • PMID: 14519675
    Ratanajamit C, Skriver MV, Norgaard M, Jepsen P, Schonheyder HC, Sorensen HT: Adverse pregnancy outcome in users of sulfamethizole during pregnancy: a population-based observational study. J Antimicrob Chemother. 2003 Nov;52(5):837-41. Epub 2003 Sep 30.
  • PMID: 12604534
    Kerrn MB, Frimodt-Moller N, Espersen F: Effects of sulfamethizole and amdinocillin against Escherichia coli strains (with various susceptibilities) in an ascending urinary tract infection mouse model. Antimicrob Agents Chemother. 2003 Mar;47(3):1002-9.
  • PMID: 2372557
    Watanabe H, Hastings JW: Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine. Biochim Biophys Acta. 1990 Jun 26;1017(3):229-34.

Contoh Produk & Brand

Produk: 1 • International brands: 4
Produk
  • Urobiotic
    Capsule • - • Oral • US • Approved
International Brands
  • Lucosil — Recip
  • Rufol — Urgo
  • Thiosulfil
  • Thiosulfil Forte

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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