Intravenous LD50 values in the mouse and rat were approximately 75 mg/kg and in the cat and dog were 40 to 80 mg/kg. Symptoms of overdosage are extensions of the pharmacologic effects of the drug. Excessive pressor effect, tachycardia, skeletal muscle hyperactivity, and enhanced deep tendon reflexes may be early signs of overdosage.
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Valsartan | Doxapram may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Doxapram may decrease the antihypertensive activities of Ramipril. |
| Esmolol | Doxapram may decrease the antihypertensive activities of Esmolol. |
| Betaxolol | Doxapram may decrease the antihypertensive activities of Betaxolol. |
| Reserpine | Doxapram may decrease the antihypertensive activities of Reserpine. |
| Remikiren | Doxapram may decrease the antihypertensive activities of Remikiren. |
| Torasemide | Doxapram may decrease the antihypertensive activities of Torasemide. |
| Guanadrel | Doxapram may decrease the antihypertensive activities of Guanadrel. |
| Metoprolol | Doxapram may decrease the antihypertensive activities of Metoprolol. |
| Isradipine | Doxapram may decrease the antihypertensive activities of Isradipine. |
| Olmesartan | Doxapram may decrease the antihypertensive activities of Olmesartan. |
| Chlorthalidone | Doxapram may decrease the antihypertensive activities of Chlorthalidone. |
| Nitroprusside | Doxapram may decrease the antihypertensive activities of Nitroprusside. |
| Atenolol | Doxapram may decrease the antihypertensive activities of Atenolol. |
| Diltiazem | Doxapram may decrease the antihypertensive activities of Diltiazem. |
| Minoxidil | Doxapram may decrease the antihypertensive activities of Minoxidil. |
| Timolol | Doxapram may decrease the antihypertensive activities of Timolol. |
| Treprostinil | Doxapram may decrease the antihypertensive activities of Treprostinil. |
| Amlodipine | Doxapram may decrease the antihypertensive activities of Amlodipine. |
| Nimodipine | Doxapram may decrease the antihypertensive activities of Nimodipine. |
| Nisoldipine | Doxapram may decrease the antihypertensive activities of Nisoldipine. |
| Bendroflumethiazide | Doxapram may decrease the antihypertensive activities of Bendroflumethiazide. |
| Prazosin | Doxapram may decrease the antihypertensive activities of Prazosin. |
| Fosinopril | Doxapram may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Doxapram may decrease the antihypertensive activities of Trandolapril. |
| Metolazone | Doxapram may decrease the antihypertensive activities of Metolazone. |
| Lercanidipine | Doxapram may decrease the antihypertensive activities of Lercanidipine. |
| Benazepril | Doxapram may decrease the antihypertensive activities of Benazepril. |
| Bosentan | Doxapram may decrease the antihypertensive activities of Bosentan. |
| Propranolol | Doxapram may decrease the antihypertensive activities of Propranolol. |
| Enalapril | Doxapram may decrease the antihypertensive activities of Enalapril. |
| Doxazosin | Doxapram may decrease the antihypertensive activities of Doxazosin. |
| Labetalol | Doxapram may decrease the antihypertensive activities of Labetalol. |
| Cyclothiazide | Doxapram may decrease the antihypertensive activities of Cyclothiazide. |
| Bisoprolol | Doxapram may decrease the antihypertensive activities of Bisoprolol. |
| Candoxatril | Doxapram may decrease the antihypertensive activities of Candoxatril. |
| Nicardipine | Doxapram may decrease the antihypertensive activities of Nicardipine. |
| Mecamylamine | Doxapram may decrease the antihypertensive activities of Mecamylamine. |
| Losartan | Doxapram may decrease the antihypertensive activities of Losartan. |
| Moexipril | Doxapram may decrease the antihypertensive activities of Moexipril. |
| Eplerenone | Doxapram may decrease the antihypertensive activities of Eplerenone. |
| Lisinopril | Doxapram may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Doxapram may decrease the antihypertensive activities of Nitroglycerin. |
| Metyrosine | Doxapram may decrease the antihypertensive activities of Metyrosine. |
| Hydroflumethiazide | Doxapram may decrease the antihypertensive activities of Hydroflumethiazide. |
| Cryptenamine | Doxapram may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Doxapram may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Doxapram may decrease the antihypertensive activities of Candesartan cilexetil. |
| Fenoldopam | Doxapram may decrease the antihypertensive activities of Fenoldopam. |
| Indapamide | Doxapram may decrease the antihypertensive activities of Indapamide. |
| Tadalafil | Doxapram may decrease the antihypertensive activities of Tadalafil. |
| Alprenolol | Doxapram may decrease the antihypertensive activities of Alprenolol. |
| Eprosartan | Doxapram may decrease the antihypertensive activities of Eprosartan. |
| Chlorothiazide | Doxapram may decrease the antihypertensive activities of Chlorothiazide. |
| Quinapril | Doxapram may decrease the antihypertensive activities of Quinapril. |
| Pindolol | Doxapram may decrease the antihypertensive activities of Pindolol. |
| Telmisartan | Doxapram may decrease the antihypertensive activities of Telmisartan. |
| Methyldopa | Doxapram may decrease the antihypertensive activities of Methyldopa. |
| Hydrochlorothiazide | Doxapram may decrease the antihypertensive activities of Hydrochlorothiazide. |
| Trichlormethiazide | Doxapram may decrease the antihypertensive activities of Trichlormethiazide. |
| Felodipine | Doxapram may decrease the antihypertensive activities of Felodipine. |
| Irbesartan | Doxapram may decrease the antihypertensive activities of Irbesartan. |
| Nitrendipine | Doxapram may decrease the antihypertensive activities of Nitrendipine. |
| Deserpidine | Doxapram may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Doxapram may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Doxapram may decrease the antihypertensive activities of Trimethaphan. |
| Diazoxide | Doxapram may decrease the antihypertensive activities of Diazoxide. |
| Carvedilol | Doxapram may decrease the antihypertensive activities of Carvedilol. |
| Bretylium | Doxapram may decrease the antihypertensive activities of Bretylium. |
| Terazosin | Doxapram may decrease the antihypertensive activities of Terazosin. |
| Guanethidine | Doxapram may decrease the antihypertensive activities of Guanethidine. |
| Acebutolol | Doxapram may decrease the antihypertensive activities of Acebutolol. |
| Captopril | Doxapram may decrease the antihypertensive activities of Captopril. |
| Nadolol | Doxapram may decrease the antihypertensive activities of Nadolol. |
| Epoprostenol | Doxapram may decrease the antihypertensive activities of Epoprostenol. |
| Bepridil | Doxapram may decrease the antihypertensive activities of Bepridil. |
| Hydralazine | Doxapram may decrease the antihypertensive activities of Hydralazine. |
| Bevantolol | Doxapram may decrease the antihypertensive activities of Bevantolol. |
| Practolol | Doxapram may decrease the antihypertensive activities of Practolol. |
| Polythiazide | Doxapram may decrease the antihypertensive activities of Polythiazide. |
| Cilazapril | Doxapram may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Doxapram may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Doxapram may decrease the antihypertensive activities of Spirapril. |
| Penbutolol | Doxapram may decrease the antihypertensive activities of Penbutolol. |
| Mibefradil | Doxapram may decrease the antihypertensive activities of Mibefradil. |
| Oxprenolol | Doxapram may decrease the antihypertensive activities of Oxprenolol. |
| Dexpropranolol | Doxapram may decrease the antihypertensive activities of Dexpropranolol. |
| Tienilic acid | Doxapram may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Doxapram may decrease the antihypertensive activities of Debrisoquine. |
| Celiprolol | Doxapram may decrease the antihypertensive activities of Celiprolol. |
| Nebivolol | Doxapram may decrease the antihypertensive activities of Nebivolol. |
| Sitaxentan | Doxapram may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Doxapram may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Doxapram may decrease the antihypertensive activities of Diethylnorspermine. |
| Nilvadipine | Doxapram may decrease the antihypertensive activities of Nilvadipine. |
| Pinacidil | Doxapram may decrease the antihypertensive activities of Pinacidil. |
| Bupranolol | Doxapram may decrease the antihypertensive activities of Bupranolol. |
| Temocapril | Doxapram may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Doxapram may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Doxapram may decrease the antihypertensive activities of Macitentan. |