Since glycylcyclines are similar to tetracyclines, they share many of the same side effects and contraindications as tetracyclines. These side effects may include nausea/vomiting, headache, photosensitivity, discoloration of growing teeth, and fetal damage.
Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Succinylcholine | The therapeutic efficacy of Succinylcholine can be increased when used in combination with Tigecycline. |
| Metocurine iodide | The therapeutic efficacy of Metocurine iodide can be increased when used in combination with Tigecycline. |
| Gallamine triethiodide | The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Tigecycline. |
| Cisatracurium | Tigecycline may increase the neuromuscular blocking activities of Cisatracurium. |
| Rocuronium | The therapeutic efficacy of Rocuronium can be increased when used in combination with Tigecycline. |
| Atracurium besylate | The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Tigecycline. |
| Doxacurium | The therapeutic efficacy of Doxacurium can be increased when used in combination with Tigecycline. |
| Mivacurium | The therapeutic efficacy of Mivacurium can be increased when used in combination with Tigecycline. |
| Decamethonium | The therapeutic efficacy of Decamethonium can be increased when used in combination with Tigecycline. |
| Metocurine | The therapeutic efficacy of Metocurine can be increased when used in combination with Tigecycline. |
| Pancuronium | The therapeutic efficacy of Pancuronium can be increased when used in combination with Tigecycline. |
| Pipecuronium | The therapeutic efficacy of Pipecuronium can be increased when used in combination with Tigecycline. |
| Vecuronium | The therapeutic efficacy of Vecuronium can be increased when used in combination with Tigecycline. |
| Rapacuronium | The therapeutic efficacy of Rapacuronium can be increased when used in combination with Tigecycline. |
| Pyrantel | The therapeutic efficacy of Pyrantel can be increased when used in combination with Tigecycline. |
| Neosaxitoxin | The therapeutic efficacy of Neosaxitoxin can be increased when used in combination with Tigecycline. |
| Atracurium | The therapeutic efficacy of Atracurium can be increased when used in combination with Tigecycline. |
| Gallamine | The therapeutic efficacy of Gallamine can be increased when used in combination with Tigecycline. |
| Alcuronium | The therapeutic efficacy of Alcuronium can be increased when used in combination with Tigecycline. |
| Tubocurarine | The therapeutic efficacy of Tubocurarine can be increased when used in combination with Tigecycline. |
| Mecamylamine | Tigecycline may increase the neuromuscular blocking activities of Mecamylamine. |
| Mipomersen | Tigecycline may increase the hepatotoxic activities of Mipomersen. |
| Flucloxacillin | The therapeutic efficacy of Flucloxacillin can be decreased when used in combination with Tigecycline. |
| Piperacillin | The therapeutic efficacy of Piperacillin can be decreased when used in combination with Tigecycline. |
| Ampicillin | The therapeutic efficacy of Ampicillin can be decreased when used in combination with Tigecycline. |
| Phenoxymethylpenicillin | The therapeutic efficacy of Phenoxymethylpenicillin can be decreased when used in combination with Tigecycline. |
| Dicloxacillin | The therapeutic efficacy of Dicloxacillin can be decreased when used in combination with Tigecycline. |
| Carbenicillin | The therapeutic efficacy of Carbenicillin can be decreased when used in combination with Tigecycline. |
| Nafcillin | The therapeutic efficacy of Nafcillin can be decreased when used in combination with Tigecycline. |
| Oxacillin | The therapeutic efficacy of Oxacillin can be decreased when used in combination with Tigecycline. |
| Hetacillin | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Tigecycline. |
| Benzylpenicilloyl polylysine | The therapeutic efficacy of Benzylpenicilloyl polylysine can be decreased when used in combination with Tigecycline. |
| Mezlocillin | The therapeutic efficacy of Mezlocillin can be decreased when used in combination with Tigecycline. |
| Cyclacillin | The therapeutic efficacy of Cyclacillin can be decreased when used in combination with Tigecycline. |
| Benzylpenicillin | The therapeutic efficacy of Benzylpenicillin can be decreased when used in combination with Tigecycline. |
| Amoxicillin | The therapeutic efficacy of Amoxicillin can be decreased when used in combination with Tigecycline. |
| Azlocillin | The therapeutic efficacy of Azlocillin can be decreased when used in combination with Tigecycline. |
| Cloxacillin | The therapeutic efficacy of Cloxacillin can be decreased when used in combination with Tigecycline. |
| Amdinocillin | The therapeutic efficacy of Amdinocillin can be decreased when used in combination with Tigecycline. |
| Bacampicillin | The therapeutic efficacy of Bacampicillin can be decreased when used in combination with Tigecycline. |
| Meticillin | The therapeutic efficacy of Meticillin can be decreased when used in combination with Tigecycline. |
| Pivampicillin | The therapeutic efficacy of Pivampicillin can be decreased when used in combination with Tigecycline. |
| Pivmecillinam | The therapeutic efficacy of Pivmecillinam can be decreased when used in combination with Tigecycline. |
| Ticarcillin | The therapeutic efficacy of Ticarcillin can be decreased when used in combination with Tigecycline. |
| Azidocillin | The therapeutic efficacy of Azidocillin can be decreased when used in combination with Tigecycline. |
| Carindacillin | The therapeutic efficacy of Carindacillin can be decreased when used in combination with Tigecycline. |
| Procaine benzylpenicillin | The therapeutic efficacy of Procaine benzylpenicillin can be decreased when used in combination with Tigecycline. |
| Sultamicillin | The therapeutic efficacy of Sultamicillin can be decreased when used in combination with Tigecycline. |
| Temocillin | The therapeutic efficacy of Temocillin can be decreased when used in combination with Tigecycline. |
| Epicillin | The therapeutic efficacy of Epicillin can be decreased when used in combination with Tigecycline. |
| Pheneticillin | The therapeutic efficacy of Pheneticillin can be decreased when used in combination with Tigecycline. |
| Carfecillin | The therapeutic efficacy of Carfecillin can be decreased when used in combination with Tigecycline. |
| Propicillin | The therapeutic efficacy of Propicillin can be decreased when used in combination with Tigecycline. |
| Clometocillin | The therapeutic efficacy of Clometocillin can be decreased when used in combination with Tigecycline. |
| Sulbenicillin | The therapeutic efficacy of Sulbenicillin can be decreased when used in combination with Tigecycline. |
| Penamecillin | The therapeutic efficacy of Penamecillin can be decreased when used in combination with Tigecycline. |
| Talampicillin | The therapeutic efficacy of Talampicillin can be decreased when used in combination with Tigecycline. |
| Aspoxicillin | The therapeutic efficacy of Aspoxicillin can be decreased when used in combination with Tigecycline. |
| Metampicillin | The therapeutic efficacy of Metampicillin can be decreased when used in combination with Tigecycline. |
| Warfarin | The serum concentration of Warfarin can be increased when it is combined with Tigecycline. |
| Acenocoumarol | The serum concentration of Acenocoumarol can be increased when it is combined with Tigecycline. |
| (R)-warfarin | The serum concentration of (R)-warfarin can be increased when it is combined with Tigecycline. |
| R,S-Warfarin alcohol | The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with Tigecycline. |
| S,R-Warfarin alcohol | The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with Tigecycline. |
| (S)-Warfarin | The serum concentration of (S)-Warfarin can be increased when it is combined with Tigecycline. |
| Bismuth subcitrate potassium | The serum concentration of Tigecycline can be decreased when it is combined with Bismuth subcitrate potassium. |
| Zinc | Zinc can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc trihydroxide | Zinc trihydroxide can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc Substituted Heme C | Zinc Substituted Heme C can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Polaprezinc | Polaprezinc can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc oxide | Zinc oxide can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc sulfate | Zinc sulfate can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc citrate | Zinc citrate can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc picolinate | Zinc picolinate can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc gluconate | Zinc gluconate can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Acetylcysteine zinc | Acetylcysteine zinc can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc ascorbate | Zinc ascorbate can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc acetate | Zinc acetate can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc glycinate | Zinc glycinate can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc chloride | Zinc chloride can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc sulfate, unspecified form | Zinc sulfate, unspecified form can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Zinc cation | Zinc cation can cause a decrease in the absorption of Tigecycline resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| BCG vaccine | The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Tigecycline. |
| Typhoid vaccine | The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Tigecycline. |
| Etonogestrel | The serum concentration of Etonogestrel can be decreased when it is combined with Tigecycline. |
| Desogestrel | The serum concentration of Desogestrel can be decreased when it is combined with Tigecycline. |
| Megestrol acetate | The serum concentration of Megestrol acetate can be decreased when it is combined with Tigecycline. |
| Levonorgestrel | The serum concentration of Levonorgestrel can be decreased when it is combined with Tigecycline. |
| Dydrogesterone | The serum concentration of Dydrogesterone can be decreased when it is combined with Tigecycline. |
| Progesterone | The serum concentration of Progesterone can be decreased when it is combined with Tigecycline. |
| Medroxyprogesterone acetate | The serum concentration of Medroxyprogesterone acetate can be decreased when it is combined with Tigecycline. |
| Norethisterone | The serum concentration of Norethisterone can be decreased when it is combined with Tigecycline. |
| Ethynodiol diacetate | The serum concentration of Ethynodiol diacetate can be decreased when it is combined with Tigecycline. |
| Norgestimate | The serum concentration of Norgestimate can be decreased when it is combined with Tigecycline. |
| Drospirenone | The serum concentration of Drospirenone can be decreased when it is combined with Tigecycline. |
| Allylestrenol | The serum concentration of Allylestrenol can be decreased when it is combined with Tigecycline. |
| Cyproterone acetate | The serum concentration of Cyproterone acetate can be decreased when it is combined with Tigecycline. |
| Norelgestromin | The serum concentration of Norelgestromin can be decreased when it is combined with Tigecycline. |
| Gestodene | The serum concentration of Gestodene can be decreased when it is combined with Tigecycline. |
| Hydroxyprogesterone caproate | The serum concentration of Hydroxyprogesterone caproate can be decreased when it is combined with Tigecycline. |