Methoxsalen

DB00553

small molecule approved

Deskripsi

A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.

Struktur Molekul 2D

Berat 216.192
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) Approximately 2 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

In both mice and man, methoxsalen is rapidly metabolized. Approximately 95% of the drug is excreted as a series of metabolites in the urine within 24 hours (Pathak et al. 1977).

Interaksi Makanan

1 Data
  • 1. Take with food. Take this medication with food or milk.

Interaksi Obat

872 Data
Porfimer sodium Methoxsalen may increase the photosensitizing activities of Porfimer sodium.
Verteporfin Methoxsalen may increase the photosensitizing activities of Verteporfin.
Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Methoxsalen.
Cyclosporine Cyclosporine may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Icosapent Icosapent may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefotiam Cefotiam may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Mesalazine Mesalazine may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefmenoxime Cefmenoxime may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefmetazole Cefmetazole may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Pamidronic acid Pamidronic acid may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Tenofovir disoproxil Tenofovir disoproxil may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Indomethacin Indomethacin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cidofovir Cidofovir may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefpiramide Cefpiramide may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ceftazidime Ceftazidime may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Loracarbef Loracarbef may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefalotin Cefalotin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ketorolac Ketorolac may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Tenoxicam Tenoxicam may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Celecoxib Celecoxib may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefotaxime Cefotaxime may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Tolmetin Tolmetin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Foscarnet Foscarnet may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Piroxicam Piroxicam may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Methotrexate Methotrexate may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cephalexin Cephalexin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Fenoprofen Fenoprofen may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Valaciclovir Valaciclovir may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Valdecoxib Valdecoxib may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Sulindac Sulindac may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Bacitracin Bacitracin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Amphotericin B Amphotericin B may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cephaloglycin Cephaloglycin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Flurbiprofen Flurbiprofen may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Adefovir dipivoxil Adefovir dipivoxil may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Pentamidine Pentamidine may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Etodolac Etodolac may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Sulfasalazine Sulfasalazine may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Phenylbutazone Phenylbutazone may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Meloxicam Meloxicam may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Carprofen Carprofen may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefaclor Cefaclor may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Diflunisal Diflunisal may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Tacrolimus Tacrolimus may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ceforanide Ceforanide may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Salicylic acid Salicylic acid may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Meclofenamic acid Meclofenamic acid may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Acetylsalicylic acid Acetylsalicylic acid may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Carboplatin Carboplatin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Oxaprozin Oxaprozin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ketoprofen Ketoprofen may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Balsalazide Balsalazide may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ibuprofen Ibuprofen may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefditoren Cefditoren may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Atazanavir Atazanavir may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Colistimethate Colistimethate may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefuroxime Cefuroxime may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefapirin Cefapirin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefadroxil Cefadroxil may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefprozil Cefprozil may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ceftriaxone Ceftriaxone may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Olsalazine Olsalazine may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Lumiracoxib Lumiracoxib may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefamandole Cefamandole may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefazolin Cefazolin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefonicid Cefonicid may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefoperazone Cefoperazone may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefotetan Cefotetan may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefoxitin Cefoxitin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ceftizoxime Ceftizoxime may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefradine Cefradine may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Magnesium salicylate Magnesium salicylate may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Salsalate Salsalate may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Choline magnesium trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefepime Cefepime may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefacetrile Cefacetrile may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ceftibuten Ceftibuten may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cefpodoxime Cefpodoxime may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Antrafenine Antrafenine may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Tiaprofenic acid Tiaprofenic acid may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Lopinavir Lopinavir may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Hydrolyzed Cephalothin Hydrolyzed Cephalothin may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cephalothin Group Cephalothin Group may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Oxyphenbutazone Oxyphenbutazone may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Latamoxef Latamoxef may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Nimesulide Nimesulide may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Benoxaprofen Benoxaprofen may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Metamizole Metamizole may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Zomepirac Zomepirac may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ceftobiprole Ceftobiprole may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Cimicoxib Cimicoxib may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Ceftaroline fosamil Ceftaroline fosamil may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Lornoxicam Lornoxicam may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Aceclofenac Aceclofenac may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Zaltoprofen Zaltoprofen may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Azapropazone Azapropazone may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Parecoxib Parecoxib may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Salicylamide Salicylamide may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Kebuzone Kebuzone may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
Isoxicam Isoxicam may decrease the excretion rate of Methoxsalen which could result in a higher serum level.

Target Protein

DNA
Cytochrome P450 2A6 CYP2A6

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 13 • International brands: 4
Produk
  • 8-mop
    Capsule, gelatin coated • 10 mg/1 • Oral • US • Approved
  • Methoxsalen
    Capsule, liquid filled • 10 mg/1 • Oral • US • Generic • Approved
  • Methoxsalen
    Capsule, liquid filled • 10 mg/1 • Oral • US • Generic • Approved
  • Methoxsalen
    Capsule, liquid filled • 10 mg/1 • Oral • US • Generic • Approved
  • Oxsoralen
    Lotion • 10 mg/1mL • Topical • US • Approved
  • Oxsoralen Cap 10mg
    Capsule • 10 mg • Oral • Canada • Approved
  • Oxsoralen Lot 10mg/ml
    Lotion • 10 mg / mL • Topical • Canada • Approved
  • Oxsoralen-Ultra
    Capsule, liquid filled • 10 mg/1 • Oral • US • Approved
Menampilkan 8 dari 13 produk.
International Brands
  • Deltasoralen — Delta
  • Meladinine — CLS Pharma
  • Meloxine
  • Ultra Mop

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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