Side effects include rash and upset stomach.
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily.
Zafirlukast blocks the action of the cysteinyl leukotrienes on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and inflammation of the breathing passages.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Loxapine | The therapeutic efficacy of Zafirlukast can be decreased when used in combination with Loxapine. |
| Cilostazol | The serum concentration of Cilostazol can be increased when it is combined with Zafirlukast. |
| Citalopram | The serum concentration of Citalopram can be increased when it is combined with Zafirlukast. |
| Flibanserin | The serum concentration of Flibanserin can be increased when it is combined with Zafirlukast. |
| Clopidogrel | The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Zafirlukast resulting in a loss in efficacy. |
| Eliglustat | The metabolism of Eliglustat can be decreased when combined with Zafirlukast. |
| Ibrutinib | The metabolism of Ibrutinib can be decreased when combined with Zafirlukast. |
| Erythromycin | The serum concentration of Zafirlukast can be decreased when it is combined with Erythromycin. |
| Colchicine | The metabolism of Colchicine can be decreased when combined with Zafirlukast. |
| Iloperidone | The metabolism of Iloperidone can be decreased when combined with Zafirlukast. |
| Retapamulin | The metabolism of Retapamulin can be decreased when combined with Zafirlukast. |
| Tofacitinib | The metabolism of Tofacitinib can be decreased when combined with Zafirlukast. |
| Vardenafil | The metabolism of Vardenafil can be decreased when combined with Zafirlukast. |
| Eszopiclone | The metabolism of Eszopiclone can be decreased when combined with Zafirlukast. |
| Zopiclone | The metabolism of Zopiclone can be decreased when combined with Zafirlukast. |
| Lovastatin | The metabolism of Lovastatin can be decreased when combined with Zafirlukast. |
| Caffeine | The serum concentration of Zafirlukast can be decreased when it is combined with Caffeine. |
| Theophylline | The serum concentration of Zafirlukast can be decreased when it is combined with Theophylline. |
| Dyphylline | The serum concentration of Zafirlukast can be decreased when it is combined with Dyphylline. |
| Pentoxifylline | The serum concentration of Zafirlukast can be decreased when it is combined with Pentoxifylline. |
| Mercaptopurine | The serum concentration of Zafirlukast can be decreased when it is combined with Mercaptopurine. |
| Aminophylline | The serum concentration of Zafirlukast can be decreased when it is combined with Aminophylline. |
| Oxtriphylline | The serum concentration of Zafirlukast can be decreased when it is combined with Oxtriphylline. |
| Theobromine | The serum concentration of Zafirlukast can be decreased when it is combined with Theobromine. |
| Fenethylline | The serum concentration of Zafirlukast can be decreased when it is combined with Fenethylline. |
| 8-azaguanine | The serum concentration of Zafirlukast can be decreased when it is combined with 8-azaguanine. |
| 7,9-Dimethylguanine | The serum concentration of Zafirlukast can be decreased when it is combined with 7,9-Dimethylguanine. |
| Xanthine | The serum concentration of Zafirlukast can be decreased when it is combined with Xanthine. |
| 7-Deazaguanine | The serum concentration of Zafirlukast can be decreased when it is combined with 7-Deazaguanine. |
| Guanine | The serum concentration of Zafirlukast can be decreased when it is combined with Guanine. |
| 9-Methylguanine | The serum concentration of Zafirlukast can be decreased when it is combined with 9-Methylguanine. |
| Peldesine | The serum concentration of Zafirlukast can be decreased when it is combined with Peldesine. |
| Hypoxanthine | The serum concentration of Zafirlukast can be decreased when it is combined with Hypoxanthine. |
| 9-Deazaguanine | The serum concentration of Zafirlukast can be decreased when it is combined with 9-Deazaguanine. |
| Propentofylline | The serum concentration of Zafirlukast can be decreased when it is combined with Propentofylline. |
| Valomaciclovir | The serum concentration of Zafirlukast can be decreased when it is combined with Valomaciclovir. |
| 3-isobutyl-1-methyl-7H-xanthine | The serum concentration of Zafirlukast can be decreased when it is combined with 3-isobutyl-1-methyl-7H-xanthine. |
| Uric acid | The serum concentration of Zafirlukast can be decreased when it is combined with Uric acid. |
| Doxofylline | The serum concentration of Zafirlukast can be decreased when it is combined with Doxofylline. |
| 6-O-benzylguanine | The serum concentration of Zafirlukast can be decreased when it is combined with 6-O-benzylguanine. |
| Lisofylline | The serum concentration of Zafirlukast can be decreased when it is combined with Lisofylline. |
| Lobucavir | The serum concentration of Zafirlukast can be decreased when it is combined with Lobucavir. |
| Cafedrine | The serum concentration of Zafirlukast can be decreased when it is combined with Cafedrine. |
| Theodrenaline | The serum concentration of Zafirlukast can be decreased when it is combined with Theodrenaline. |
| Bamifylline | The serum concentration of Zafirlukast can be decreased when it is combined with Bamifylline. |
| Proxyphylline | The serum concentration of Zafirlukast can be decreased when it is combined with Proxyphylline. |
| Acefylline | The serum concentration of Zafirlukast can be decreased when it is combined with Acefylline. |
| Etamiphylline | The serum concentration of Zafirlukast can be decreased when it is combined with Etamiphylline. |
| Pentifylline | The serum concentration of Zafirlukast can be decreased when it is combined with Pentifylline. |
| Bufylline | The serum concentration of Zafirlukast can be decreased when it is combined with Bufylline. |
| Bromotheophylline | The serum concentration of Zafirlukast can be decreased when it is combined with Bromotheophylline. |
| Furafylline | The serum concentration of Zafirlukast can be decreased when it is combined with Furafylline. |
| 8-chlorotheophylline | The serum concentration of Zafirlukast can be decreased when it is combined with 8-chlorotheophylline. |
| PCS-499 | The serum concentration of Zafirlukast can be decreased when it is combined with PCS-499. |
| Alfuzosin | The metabolism of Alfuzosin can be decreased when combined with Zafirlukast. |
| Alprazolam | The metabolism of Alprazolam can be decreased when combined with Zafirlukast. |
| Warfarin | The serum concentration of Warfarin can be increased when it is combined with Zafirlukast. |
| Acenocoumarol | The serum concentration of Acenocoumarol can be increased when it is combined with Zafirlukast. |
| (R)-warfarin | The serum concentration of (R)-warfarin can be increased when it is combined with Zafirlukast. |
| R,S-Warfarin alcohol | The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with Zafirlukast. |
| S,R-Warfarin alcohol | The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with Zafirlukast. |
| (S)-Warfarin | The serum concentration of (S)-Warfarin can be increased when it is combined with Zafirlukast. |
| Midazolam | The serum concentration of Midazolam can be increased when it is combined with Zafirlukast. |
| Tacrolimus | The serum concentration of Tacrolimus can be increased when it is combined with Zafirlukast. |
| Atorvastatin | The metabolism of Atorvastatin can be decreased when combined with Zafirlukast. |
| Pantoprazole | The metabolism of Pantoprazole can be decreased when combined with Zafirlukast. |
| Pentobarbital | The metabolism of Pentobarbital can be decreased when combined with Zafirlukast. |
| Clobazam | The serum concentration of Clobazam can be increased when it is combined with Zafirlukast. |
| Timolol | The metabolism of Timolol can be decreased when combined with Zafirlukast. |
| Carisoprodol | The metabolism of Carisoprodol can be decreased when combined with Zafirlukast. |
| Progesterone | The metabolism of Progesterone can be decreased when combined with Zafirlukast. |
| Quinine | The metabolism of Quinine can be decreased when combined with Zafirlukast. |
| Fluoxetine | The metabolism of Fluoxetine can be decreased when combined with Zafirlukast. |
| Albendazole | The metabolism of Albendazole can be decreased when combined with Zafirlukast. |
| Doxazosin | The metabolism of Doxazosin can be decreased when combined with Zafirlukast. |
| Thiopental | The metabolism of Thiopental can be decreased when combined with Zafirlukast. |
| Thioridazine | The metabolism of Thioridazine can be decreased when combined with Zafirlukast. |
| Esomeprazole | The metabolism of Esomeprazole can be decreased when combined with Zafirlukast. |
| Methylphenobarbital | The metabolism of Methylphenobarbital can be decreased when combined with Zafirlukast. |
| Zonisamide | The metabolism of Zonisamide can be decreased when combined with Zafirlukast. |
| Praziquantel | The metabolism of Praziquantel can be decreased when combined with Zafirlukast. |
| Rabeprazole | The metabolism of Rabeprazole can be decreased when combined with Zafirlukast. |
| Proguanil | The metabolism of Proguanil can be decreased when combined with Zafirlukast. |
| Escitalopram | The metabolism of Escitalopram can be decreased when combined with Zafirlukast. |
| St. John's Wort | The metabolism of St. John's Wort can be decreased when combined with Zafirlukast. |
| Hexobarbital | The metabolism of Hexobarbital can be decreased when combined with Zafirlukast. |
| Barbital | The metabolism of Barbital can be decreased when combined with Zafirlukast. |
| Methsuximide | The metabolism of Methsuximide can be decreased when combined with Zafirlukast. |
| Dexlansoprazole | The metabolism of Dexlansoprazole can be decreased when combined with Zafirlukast. |
| Lacosamide | The metabolism of Lacosamide can be decreased when combined with Zafirlukast. |
| Etravirine | The metabolism of Etravirine can be decreased when combined with Zafirlukast. |
| Artemether | The metabolism of Artemether can be decreased when combined with Zafirlukast. |
| Etizolam | The metabolism of Etizolam can be decreased when combined with Zafirlukast. |
| Triclabendazole | The metabolism of Triclabendazole can be decreased when combined with Zafirlukast. |
| Lynestrenol | The metabolism of Lynestrenol can be decreased when combined with Zafirlukast. |
| Dexrabeprazole | The metabolism of Dexrabeprazole can be decreased when combined with Zafirlukast. |
| Primidone | The metabolism of Primidone can be decreased when combined with Zafirlukast. |
| Voriconazole | The metabolism of Voriconazole can be decreased when combined with Zafirlukast. |
| Formoterol | The metabolism of Formoterol can be decreased when combined with Zafirlukast. |
| Glyburide | The metabolism of Glyburide can be decreased when combined with Zafirlukast. |