Peringatan Keamanan

Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness.

Triflupromazine

DB00508

small molecule approved vet_approved

Deskripsi

A phenothiazine used as an antipsychotic agent and as an antiemetic.

Struktur Molekul 2D

Berat 352.417
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Absorption may be erratic and peak plasma concentrations show large interindividual differences.

Metabolisme

Hepatic.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1217 Data
Buprenorphine Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
Hydrocodone Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
Magnesium sulfate The therapeutic efficacy of Triflupromazine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
Mirtazapine Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
Orphenadrine Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
Rotigotine Triflupromazine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Triflupromazine.
Sodium oxybate Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
Thalidomide Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Aclidinium The risk or severity of adverse effects can be increased when Triflupromazine is combined with Aclidinium.
Mianserin Mianserin may increase the anticholinergic activities of Triflupromazine.
Mirabegron The risk or severity of urinary retention can be increased when Triflupromazine is combined with Mirabegron.
Potassium chloride The risk or severity of gastrointestinal ulceration can be increased when Triflupromazine is combined with Potassium chloride.
Pramlintide The risk or severity of reduced gastrointestinal motility can be increased when Pramlintide is combined with Triflupromazine.
Secretin porcine The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Triflupromazine.
Tiotropium The risk or severity of adverse effects can be increased when Triflupromazine is combined with Tiotropium.
Topiramate The risk or severity of hyperthermia and oligohydrosis can be increased when Triflupromazine is combined with Topiramate.
Umeclidinium The risk or severity of adverse effects can be increased when Triflupromazine is combined with Umeclidinium.
Amisulpride Triflupromazine may increase the antipsychotic activities of Amisulpride.
Methylphenidate The risk or severity of adverse effects can be increased when Triflupromazine is combined with Methylphenidate.
Dexmethylphenidate The risk or severity of adverse effects can be increased when Triflupromazine is combined with Dexmethylphenidate.
Metoclopramide The risk or severity of adverse effects can be increased when Metoclopramide is combined with Triflupromazine.
Quinagolide The therapeutic efficacy of Quinagolide can be decreased when used in combination with Triflupromazine.
Sulpiride Triflupromazine may increase the antipsychotic activities of Sulpiride.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Triflupromazine.
Lithium citrate Lithium citrate may increase the neurotoxic activities of Triflupromazine.
Lithium hydroxide Lithium hydroxide may increase the neurotoxic activities of Triflupromazine.
Mequitazine Triflupromazine may increase the arrhythmogenic activities of Mequitazine.
Thiopental The risk or severity of adverse effects can be increased when Triflupromazine is combined with Thiopental.
Glycopyrronium The risk or severity of adverse effects can be increased when Triflupromazine is combined with Glycopyrronium.
Dipyridamole The therapeutic efficacy of Triflupromazine can be decreased when used in combination with Dipyridamole.
Ephedrine Triflupromazine may increase the neuromuscular blocking activities of Ephedrine.
Clevidipine Triflupromazine may increase the neuromuscular blocking activities of Clevidipine.
Sar9, Met (O2)11-Substance P Triflupromazine may increase the neuromuscular blocking activities of Sar9, Met (O2)11-Substance P.
Moxisylyte Triflupromazine may increase the neuromuscular blocking activities of Moxisylyte.
Propacetamol Triflupromazine may increase the neuromuscular blocking activities of Propacetamol.
Cocaine Triflupromazine may increase the neuromuscular blocking activities of Cocaine.
Trimethaphan Triflupromazine may increase the neuromuscular blocking activities of Trimethaphan.
Doxacurium Triflupromazine may increase the neuromuscular blocking activities of Doxacurium.
Chloroprocaine Triflupromazine may increase the neuromuscular blocking activities of Chloroprocaine.
Tubocurarine Triflupromazine may increase the neuromuscular blocking activities of Tubocurarine.
Bambuterol Triflupromazine may increase the neuromuscular blocking activities of Bambuterol.
Butyrylthiocholine Triflupromazine may increase the neuromuscular blocking activities of Butyrylthiocholine.
Oxybuprocaine Triflupromazine may increase the neuromuscular blocking activities of Oxybuprocaine.
Benzonatate Triflupromazine may increase the neuromuscular blocking activities of Benzonatate.
Dicoumarol The risk or severity of adverse effects can be increased when Triflupromazine is combined with Dicoumarol.
Phenindione The risk or severity of adverse effects can be increased when Triflupromazine is combined with Phenindione.
Warfarin The risk or severity of adverse effects can be increased when Triflupromazine is combined with Warfarin.
Phenprocoumon The risk or severity of adverse effects can be increased when Triflupromazine is combined with Phenprocoumon.
Acenocoumarol The risk or severity of adverse effects can be increased when Triflupromazine is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of adverse effects can be increased when Triflupromazine is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of adverse effects can be increased when Triflupromazine is combined with Coumarin.
(R)-warfarin The risk or severity of adverse effects can be increased when Triflupromazine is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of adverse effects can be increased when Triflupromazine is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of adverse effects can be increased when Triflupromazine is combined with Fluindione.
Clorindione The risk or severity of adverse effects can be increased when Triflupromazine is combined with Clorindione.
Diphenadione The risk or severity of adverse effects can be increased when Triflupromazine is combined with Diphenadione.
Tioclomarol The risk or severity of adverse effects can be increased when Triflupromazine is combined with Tioclomarol.
(S)-Warfarin The risk or severity of adverse effects can be increased when Triflupromazine is combined with (S)-Warfarin.
Metyrosine The risk or severity of extrapyramidal symptoms and CNS depression can be increased when Metyrosine is combined with Triflupromazine.
Succinylcholine The metabolism of Succinylcholine can be decreased when combined with Triflupromazine.
Botulinum toxin type A The risk or severity of adverse effects can be increased when Triflupromazine is combined with Botulinum toxin type A.
Glucagon Triflupromazine may increase the gastrointestinal motility reducing activities of Glucagon.
Botulinum toxin type B The risk or severity of adverse effects can be increased when Triflupromazine is combined with Botulinum toxin type B.
Eluxadoline The risk or severity of constipation can be increased when Triflupromazine is combined with Eluxadoline.
Ramosetron The risk or severity of constipation can be increased when Triflupromazine is combined with Ramosetron.
Ethanol Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Triflupromazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
Zimelidine The risk or severity of adverse effects can be increased when Triflupromazine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Triflupromazine is combined with Dapoxetine.
Seproxetine The risk or severity of adverse effects can be increased when Triflupromazine is combined with Seproxetine.
Fluvoxamine The risk or severity of adverse effects can be increased when Triflupromazine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Triflupromazine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Triflupromazine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Triflupromazine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Triflupromazine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Triflupromazine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Triflupromazine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Triflupromazine is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Triflupromazine is combined with Escitalopram.
Milnacipran The risk or severity of adverse effects can be increased when Triflupromazine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Triflupromazine is combined with Desvenlafaxine.
Levomilnacipran The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Triflupromazine.
Indalpine The risk or severity of adverse effects can be increased when Triflupromazine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Triflupromazine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Triflupromazine is combined with Alaproclate.
Esmolol The serum concentration of Esmolol can be increased when it is combined with Triflupromazine.

Target Protein

D(2) dopamine receptor DRD2
D(1A) dopamine receptor DRD1
5-hydroxytryptamine receptor 2B HTR2B
Muscarinic acetylcholine receptor M1 CHRM1
Muscarinic acetylcholine receptor M2 CHRM2

Referensi & Sumber

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Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Vesprin — Bristol Myers Squibb

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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