Oral, rat LD50: 109±4 mg/kg
An opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties. It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants. (From Martindale, The Extra Pharmacopoeia, 30th ed, p683)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Methylnaltrexone | Levallorphan may increase the opioid antagonism activities of Methylnaltrexone. |
| Naloxegol | Levallorphan may increase the opioid antagonism activities of Naloxegol. |
| Tramadol | The therapeutic efficacy of Tramadol can be decreased when used in combination with Levallorphan. |
| Morphine | The therapeutic efficacy of Morphine can be decreased when used in combination with Levallorphan. |
| Codeine | The therapeutic efficacy of Codeine can be decreased when used in combination with Levallorphan. |
| Hydromorphone | The therapeutic efficacy of Hydromorphone can be decreased when used in combination with Levallorphan. |
| Methadone | The therapeutic efficacy of Methadone can be decreased when used in combination with Levallorphan. |
| Meperidine | The therapeutic efficacy of Meperidine can be decreased when used in combination with Levallorphan. |
| Oxycodone | The therapeutic efficacy of Oxycodone can be decreased when used in combination with Levallorphan. |
| Butorphanol | The therapeutic efficacy of Butorphanol can be decreased when used in combination with Levallorphan. |
| Dextropropoxyphene | The therapeutic efficacy of Dextropropoxyphene can be decreased when used in combination with Levallorphan. |
| Pentazocine | The therapeutic efficacy of Pentazocine can be decreased when used in combination with Levallorphan. |
| Naltrexone | The therapeutic efficacy of Naltrexone can be decreased when used in combination with Levallorphan. |
| Sufentanil | The therapeutic efficacy of Sufentanil can be decreased when used in combination with Levallorphan. |
| Alfentanil | The therapeutic efficacy of Alfentanil can be decreased when used in combination with Levallorphan. |
| Fentanyl | The therapeutic efficacy of Fentanyl can be decreased when used in combination with Levallorphan. |
| Nalbuphine | The therapeutic efficacy of Nalbuphine can be decreased when used in combination with Levallorphan. |
| Levorphanol | The therapeutic efficacy of Levorphanol can be decreased when used in combination with Levallorphan. |
| Remifentanil | The therapeutic efficacy of Remifentanil can be decreased when used in combination with Levallorphan. |
| Buprenorphine | The therapeutic efficacy of Buprenorphine can be decreased when used in combination with Levallorphan. |
| Hydrocodone | The therapeutic efficacy of Hydrocodone can be decreased when used in combination with Levallorphan. |
| Diphenoxylate | The therapeutic efficacy of Diphenoxylate can be decreased when used in combination with Levallorphan. |
| Oxymorphone | The therapeutic efficacy of Oxymorphone can be decreased when used in combination with Levallorphan. |
| Dezocine | The therapeutic efficacy of Dezocine can be decreased when used in combination with Levallorphan. |
| Levacetylmethadol | The therapeutic efficacy of Levacetylmethadol can be decreased when used in combination with Levallorphan. |
| Methadyl acetate | The therapeutic efficacy of Methadyl acetate can be decreased when used in combination with Levallorphan. |
| Dihydroetorphine | The therapeutic efficacy of Dihydroetorphine can be decreased when used in combination with Levallorphan. |
| Diamorphine | The therapeutic efficacy of Diamorphine can be decreased when used in combination with Levallorphan. |
| Bezitramide | The therapeutic efficacy of Bezitramide can be decreased when used in combination with Levallorphan. |
| Ethylmorphine | The therapeutic efficacy of Ethylmorphine can be decreased when used in combination with Levallorphan. |
| Etorphine | The therapeutic efficacy of Etorphine can be decreased when used in combination with Levallorphan. |
| Dextromoramide | The therapeutic efficacy of Dextromoramide can be decreased when used in combination with Levallorphan. |
| Desomorphine | The therapeutic efficacy of Desomorphine can be decreased when used in combination with Levallorphan. |
| Carfentanil | The therapeutic efficacy of Carfentanil can be decreased when used in combination with Levallorphan. |
| Dihydrocodeine | The therapeutic efficacy of Dihydrocodeine can be decreased when used in combination with Levallorphan. |
| Alphacetylmethadol | The therapeutic efficacy of Alphacetylmethadol can be decreased when used in combination with Levallorphan. |
| Dihydromorphine | The therapeutic efficacy of Dihydromorphine can be decreased when used in combination with Levallorphan. |
| Tapentadol | The therapeutic efficacy of Tapentadol can be decreased when used in combination with Levallorphan. |
| Ketobemidone | The therapeutic efficacy of Ketobemidone can be decreased when used in combination with Levallorphan. |
| DPDPE | The therapeutic efficacy of DPDPE can be decreased when used in combination with Levallorphan. |
| Lofentanil | The therapeutic efficacy of Lofentanil can be decreased when used in combination with Levallorphan. |
| Eluxadoline | The therapeutic efficacy of Eluxadoline can be decreased when used in combination with Levallorphan. |
| Opium | The therapeutic efficacy of Opium can be decreased when used in combination with Levallorphan. |
| Normethadone | The therapeutic efficacy of Normethadone can be decreased when used in combination with Levallorphan. |
| Piritramide | The therapeutic efficacy of Piritramide can be decreased when used in combination with Levallorphan. |
| Alphaprodine | The therapeutic efficacy of Alphaprodine can be decreased when used in combination with Levallorphan. |
| Nicomorphine | The therapeutic efficacy of Nicomorphine can be decreased when used in combination with Levallorphan. |
| Meptazinol | The therapeutic efficacy of Meptazinol can be decreased when used in combination with Levallorphan. |
| Phenoperidine | The therapeutic efficacy of Phenoperidine can be decreased when used in combination with Levallorphan. |
| Phenazocine | The therapeutic efficacy of Phenazocine can be decreased when used in combination with Levallorphan. |
| Tilidine | The therapeutic efficacy of Tilidine can be decreased when used in combination with Levallorphan. |
| Carfentanil, C-11 | The therapeutic efficacy of Carfentanil, C-11 can be decreased when used in combination with Levallorphan. |
| Benzhydrocodone | The therapeutic efficacy of Benzhydrocodone can be decreased when used in combination with Levallorphan. |
| Oliceridine | The therapeutic efficacy of Oliceridine can be decreased when used in combination with Levallorphan. |