Gallamine triethiodide

DB00483

small molecule approved

Deskripsi

A synthetic nondepolarizing blocking drug. The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. It should be used cautiously in patients at risk from increased heart rate but may be preferred for patients with bradycardia. (From AMA Drug Evaluations Annual, 1992, p198)

Struktur Molekul 2D

Berat 891.5291
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1264 Data
Buprenorphine Gallamine triethiodide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Gallamine triethiodide.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Gallamine triethiodide.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Gallamine triethiodide.
Hydrocodone Gallamine triethiodide may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Gallamine triethiodide.
Magnesium sulfate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Gallamine triethiodide may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Gallamine triethiodide may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Gallamine triethiodide.
Mirtazapine Gallamine triethiodide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Gallamine triethiodide.
Orphenadrine Gallamine triethiodide may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Gallamine triethiodide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Gallamine triethiodide.
Pramipexole Gallamine triethiodide may increase the sedative activities of Pramipexole.
Ropinirole Gallamine triethiodide may increase the sedative activities of Ropinirole.
Rotigotine Gallamine triethiodide may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Gallamine triethiodide.
Sodium oxybate The risk or severity of CNS depression can be increased when Gallamine triethiodide is combined with Sodium oxybate.
Suvorexant Gallamine triethiodide may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Gallamine triethiodide.
Thalidomide Gallamine triethiodide may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Gallamine triethiodide may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Capreomycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Capreomycin.
Cyclosporine The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Cyclosporine.
Doxycycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Doxycycline.
Lymecycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Lymecycline.
Framycetin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Framycetin.
Clomocycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Clomocycline.
Quinine The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Quinine.
Vancomycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Vancomycin.
Tigecycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Tigecycline.
Oxytetracycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Oxytetracycline.
Chloroquine The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Chloroquine.
Demeclocycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Demeclocycline.
Tobramycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Tobramycin.
Tetracycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Tetracycline.
Gentamicin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Gentamicin.
Etacrynic acid The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Etacrynic acid.
Metacycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Metacycline.
Netilmicin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Netilmicin.
Neomycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Neomycin.
Streptomycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Streptomycin.
Colistimethate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Colistimethate.
Kanamycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Kanamycin.
Rolitetracycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Rolitetracycline.
Magnesium oxide The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium oxide.
Magnesium cation The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium cation.
Paromomycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Paromomycin.
Lincomycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Lincomycin.
Ribostamycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Ribostamycin.
Geneticin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Geneticin.
Apramycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Apramycin.
Gentamicin C1a The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Gentamicin C1a.
Neamine The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Neamine.
Arbekacin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Arbekacin.
Viomycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Viomycin.
Puromycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Puromycin.
Magnesium hydroxide The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium hydroxide.
Magnesium trisilicate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium trisilicate.
Magnesium chloride The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium chloride.
Magnesium acetate tetrahydrate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium acetate tetrahydrate.
Magnesium carbonate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium carbonate.
Magnesium citrate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium citrate.
Magnesium glycinate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium glycinate.
Magnesium Aluminum Silicate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium Aluminum Silicate.
Dihydrostreptomycin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Dihydrostreptomycin.
Hygromycin B The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Hygromycin B.
Sisomicin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Sisomicin.
Plazomicin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Plazomicin.
Magnesium silicate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium silicate.
Penimepicycline The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Penimepicycline.
Magnesium aspartate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium aspartate.
Isepamicin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Isepamicin.
Magnesium gluconate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium gluconate.
Magnesium orotate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium orotate.
Magnesium phosphate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium phosphate.
Magnesium acetate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium acetate.
Mecamylamine The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Mecamylamine.
Quinidine The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Quinidine.
Procainamide The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Procainamide.
Dantrolene The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Dantrolene.
Piperacillin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Piperacillin.
Magnesium stearate The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Magnesium stearate.
Colistin The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Colistin.
Aclidinium The risk or severity of adverse effects can be increased when Gallamine triethiodide is combined with Aclidinium.
Mianserin Mianserin may increase the anticholinergic activities of Gallamine triethiodide.
Mirabegron The risk or severity of urinary retention can be increased when Gallamine triethiodide is combined with Mirabegron.
Potassium chloride The risk or severity of gastrointestinal ulceration can be increased when Gallamine triethiodide is combined with Potassium chloride.
Pramlintide The risk or severity of reduced gastrointestinal motility can be increased when Pramlintide is combined with Gallamine triethiodide.
Secretin porcine The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Gallamine triethiodide.
Tiotropium The risk or severity of adverse effects can be increased when Gallamine triethiodide is combined with Tiotropium.
Topiramate The risk or severity of hyperthermia and oligohydrosis can be increased when Gallamine triethiodide is combined with Topiramate.
Umeclidinium The risk or severity of adverse effects can be increased when Gallamine triethiodide is combined with Umeclidinium.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Gallamine triethiodide.
Glycopyrronium The risk or severity of adverse effects can be increased when Gallamine triethiodide is combined with Glycopyrronium.
Dipyridamole The therapeutic efficacy of Gallamine triethiodide can be decreased when used in combination with Dipyridamole.
Ephedrine Gallamine triethiodide may increase the neuromuscular blocking activities of Ephedrine.
Sar9, Met (O2)11-Substance P Gallamine triethiodide may increase the neuromuscular blocking activities of Sar9, Met (O2)11-Substance P.

Target Protein

Muscarinic acetylcholine receptor M2 CHRM2
Acetylcholinesterase ACHE
Neuronal acetylcholine receptor subunit alpha-2 CHRNA2
Muscarinic acetylcholine receptor M1 CHRM1
Muscarinic acetylcholine receptor M5 CHRM5

Referensi & Sumber

Synthesis reference: Fourneau, E.; U.S.Patent 2,544,076; March 6, 1951; assigned to Societe des Usines Chimiques Rhone-Poulenc, France.

Contoh Produk & Brand

Produk: 1 • International brands: 4
Produk
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    Liquid • 20 mg / mL • Intravenous • Canada • Approved
International Brands
  • Flaxedil — Sanofi-Aventis
  • Myraxan — Yoo Young
  • Sincurarina — Carlo Erba
  • Tricuran

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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