Enoxacin

DB00467

small molecule approved investigational

Deskripsi

A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.

Struktur Molekul 2D

Berat 320.3189
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) Plasma half-life is 3 to 6 hours.
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Rapidly absorbed following oral administration, with an absolute oral bioavailability of approximately 90%.

Metabolisme

Hepatic. Some isozymes of the cytochrome P-450 hepatic microsomal enzyme system are inhibited by enoxacin. After a single dose, greater than 40% was recovered in urine by 48 hours as unchanged drug.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

936 Data
Didanosine Didanosine can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Probenecid Probenecid may decrease the excretion rate of Enoxacin which could result in a higher serum level.
Quinapril Quinapril can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium acetate Calcium acetate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron Dextran Iron Dextran can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium Calcium can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum carbonate Lanthanum carbonate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltose Ferric carboxymaltose can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron sucrose Iron sucrose can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric pyrophosphate Ferric pyrophosphate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium citrate Calcium citrate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium gluconate Calcium gluconate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric sulfate Ferric sulfate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cation Ferric cation can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Tetraferric tricitrate decahydrate Tetraferric tricitrate decahydrate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum III cation Lanthanum III cation can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium polycarbophil Calcium polycarbophil can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric oxyhydroxide Ferric oxyhydroxide can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sucralfate Sucralfate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Enoxacin.
Nitrofurantoin The therapeutic efficacy of Enoxacin can be decreased when used in combination with Nitrofurantoin.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Enoxacin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Enoxacin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Enoxacin.
Insulin human The therapeutic efficacy of Insulin human can be increased when used in combination with Enoxacin.
Insulin lispro The therapeutic efficacy of Insulin lispro can be increased when used in combination with Enoxacin.
Insulin pork The therapeutic efficacy of Insulin pork can be increased when used in combination with Enoxacin.
Troglitazone The therapeutic efficacy of Troglitazone can be increased when used in combination with Enoxacin.
Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Enoxacin.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Enoxacin.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Enoxacin.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Enoxacin.
Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Enoxacin.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Enoxacin.
Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Enoxacin.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Enoxacin.
Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Enoxacin.
Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Enoxacin.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Enoxacin.
Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Enoxacin.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Enoxacin.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Enoxacin.
Sulfamethoxazole The therapeutic efficacy of Sulfamethoxazole can be increased when used in combination with Enoxacin.
Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Enoxacin.
Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Enoxacin.
Gliclazide The therapeutic efficacy of Gliclazide can be increased when used in combination with Enoxacin.
Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Enoxacin.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Enoxacin.
Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Enoxacin.
Gliquidone The therapeutic efficacy of Gliquidone can be increased when used in combination with Enoxacin.
Mitiglinide The therapeutic efficacy of Mitiglinide can be increased when used in combination with Enoxacin.
Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Enoxacin.
Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Enoxacin.
Exenatide The therapeutic efficacy of Exenatide can be increased when used in combination with Enoxacin.
Mecasermin The therapeutic efficacy of Mecasermin can be increased when used in combination with Enoxacin.
Pramlintide The therapeutic efficacy of Pramlintide can be increased when used in combination with Enoxacin.
Glisoxepide The therapeutic efficacy of Glisoxepide can be increased when used in combination with Enoxacin.
Insulin aspart The therapeutic efficacy of Insulin aspart can be increased when used in combination with Enoxacin.
Insulin glulisine The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Enoxacin.
Glymidine The therapeutic efficacy of Glymidine can be increased when used in combination with Enoxacin.
AICA ribonucleotide The therapeutic efficacy of AICA ribonucleotide can be increased when used in combination with Enoxacin.
Buformin The therapeutic efficacy of Buformin can be increased when used in combination with Enoxacin.
Vildagliptin The therapeutic efficacy of Vildagliptin can be increased when used in combination with Enoxacin.
Voglibose The therapeutic efficacy of Voglibose can be increased when used in combination with Enoxacin.
NN344 The therapeutic efficacy of NN344 can be increased when used in combination with Enoxacin.
AMG-222 The therapeutic efficacy of AMG-222 can be increased when used in combination with Enoxacin.
Bisegliptin The therapeutic efficacy of Bisegliptin can be increased when used in combination with Enoxacin.
Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Enoxacin.
Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Enoxacin.
Liraglutide The therapeutic efficacy of Liraglutide can be increased when used in combination with Enoxacin.
Gosogliptin The therapeutic efficacy of Gosogliptin can be increased when used in combination with Enoxacin.
Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Enoxacin.
Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Enoxacin.
Glibornuride The therapeutic efficacy of Glibornuride can be increased when used in combination with Enoxacin.
Benfluorex The therapeutic efficacy of Benfluorex can be increased when used in combination with Enoxacin.
Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Enoxacin.
Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Enoxacin.
Dulaglutide The therapeutic efficacy of Dulaglutide can be increased when used in combination with Enoxacin.
Lobeglitazone The therapeutic efficacy of Lobeglitazone can be increased when used in combination with Enoxacin.
Netoglitazone The therapeutic efficacy of Netoglitazone can be increased when used in combination with Enoxacin.
Rivoglitazone The therapeutic efficacy of Rivoglitazone can be increased when used in combination with Enoxacin.
Ciglitazone The therapeutic efficacy of Ciglitazone can be increased when used in combination with Enoxacin.
Lixisenatide The therapeutic efficacy of Lixisenatide can be increased when used in combination with Enoxacin.
Insulin degludec The therapeutic efficacy of Insulin degludec can be increased when used in combination with Enoxacin.
Insulin peglispro The therapeutic efficacy of Insulin peglispro can be increased when used in combination with Enoxacin.
Insulin tregopil The therapeutic efficacy of Insulin tregopil can be increased when used in combination with Enoxacin.
Ipragliflozin The therapeutic efficacy of Ipragliflozin can be increased when used in combination with Enoxacin.
Dutogliptin The therapeutic efficacy of Dutogliptin can be increased when used in combination with Enoxacin.
Allicin The therapeutic efficacy of Allicin can be increased when used in combination with Enoxacin.
Tofogliflozin The therapeutic efficacy of Tofogliflozin can be increased when used in combination with Enoxacin.
Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Enoxacin.
2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Enoxacin.
Teneligliptin The therapeutic efficacy of Teneligliptin can be increased when used in combination with Enoxacin.
Omarigliptin The therapeutic efficacy of Omarigliptin can be increased when used in combination with Enoxacin.
Carmegliptin The therapeutic efficacy of Carmegliptin can be increased when used in combination with Enoxacin.
Gemigliptin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Enoxacin.
Anagliptin The therapeutic efficacy of Anagliptin can be increased when used in combination with Enoxacin.
Evogliptin The therapeutic efficacy of Evogliptin can be increased when used in combination with Enoxacin.

Target Protein

DNA topoisomerase 2-beta TOP2B
DNA gyrase subunit A gyrA
DNA topoisomerase 4 subunit A parC
DNA topoisomerase 2-alpha TOP2A

Referensi & Sumber

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Contoh Produk & Brand

Produk: 0 • International brands: 12
International Brands
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  • Gyramid

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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