The intravenous LD50 of droperidol is 20-43 mg/kg in mice; 30 mg/kg in rats; 25 mg/kg in dogs and 11-13 mg/kg in rabbits. The intramuscular LD50 of droperidol is 195 mg/kg in mice, 104-110 mg/kg in rats; 97 mg/kg in rabbits and 200 mg/kg in guinea pigs. The manifestations of droperidol overdosage are an extension of its pharmacologic actions.
A butyrophenone with general properties similar to those of haloperidol. It is used in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Ivabradine | Ivabradine may increase the QTc-prolonging activities of Droperidol. |
| Valsartan | Droperidol may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Droperidol may decrease the antihypertensive activities of Ramipril. |
| Remikiren | Droperidol may decrease the antihypertensive activities of Remikiren. |
| Torasemide | Droperidol may decrease the antihypertensive activities of Torasemide. |
| Guanadrel | Droperidol may decrease the antihypertensive activities of Guanadrel. |
| Olmesartan | Droperidol may decrease the antihypertensive activities of Olmesartan. |
| Chlorthalidone | Droperidol may decrease the antihypertensive activities of Chlorthalidone. |
| Nitroprusside | Droperidol may decrease the antihypertensive activities of Nitroprusside. |
| Minoxidil | Droperidol may decrease the antihypertensive activities of Minoxidil. |
| Bendroflumethiazide | Droperidol may decrease the antihypertensive activities of Bendroflumethiazide. |
| Fosinopril | Droperidol may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Droperidol may decrease the antihypertensive activities of Trandolapril. |
| Metolazone | Droperidol may decrease the antihypertensive activities of Metolazone. |
| Benazepril | Droperidol may decrease the antihypertensive activities of Benazepril. |
| Bosentan | Droperidol may decrease the antihypertensive activities of Bosentan. |
| Enalapril | Droperidol may decrease the antihypertensive activities of Enalapril. |
| Cyclothiazide | Droperidol may decrease the antihypertensive activities of Cyclothiazide. |
| Candoxatril | Droperidol may decrease the antihypertensive activities of Candoxatril. |
| Mecamylamine | Droperidol may decrease the antihypertensive activities of Mecamylamine. |
| Eplerenone | Droperidol may decrease the antihypertensive activities of Eplerenone. |
| Lisinopril | Droperidol may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Droperidol may decrease the antihypertensive activities of Nitroglycerin. |
| Hydroflumethiazide | Droperidol may decrease the antihypertensive activities of Hydroflumethiazide. |
| Cryptenamine | Droperidol may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Droperidol may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Droperidol may decrease the antihypertensive activities of Candesartan cilexetil. |
| Eprosartan | Droperidol may decrease the antihypertensive activities of Eprosartan. |
| Chlorothiazide | Droperidol may decrease the antihypertensive activities of Chlorothiazide. |
| Quinapril | Droperidol may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Droperidol may decrease the antihypertensive activities of Telmisartan. |
| Trichlormethiazide | Droperidol may decrease the antihypertensive activities of Trichlormethiazide. |
| Irbesartan | Droperidol may decrease the antihypertensive activities of Irbesartan. |
| Deserpidine | Droperidol may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Droperidol may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Droperidol may decrease the antihypertensive activities of Trimethaphan. |
| Diazoxide | Droperidol may decrease the antihypertensive activities of Diazoxide. |
| Guanethidine | Droperidol may decrease the antihypertensive activities of Guanethidine. |
| Captopril | Droperidol may decrease the antihypertensive activities of Captopril. |
| Epoprostenol | Droperidol may decrease the antihypertensive activities of Epoprostenol. |
| Hydralazine | Droperidol may decrease the antihypertensive activities of Hydralazine. |
| Polythiazide | Droperidol may decrease the antihypertensive activities of Polythiazide. |
| Cilazapril | Droperidol may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Droperidol may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Droperidol may decrease the antihypertensive activities of Spirapril. |
| Tienilic acid | Droperidol may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Droperidol may decrease the antihypertensive activities of Debrisoquine. |
| Sitaxentan | Droperidol may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Droperidol may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Droperidol may decrease the antihypertensive activities of Diethylnorspermine. |
| Pinacidil | Droperidol may decrease the antihypertensive activities of Pinacidil. |
| Temocapril | Droperidol may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Droperidol may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Droperidol may decrease the antihypertensive activities of Macitentan. |
| Aliskiren | Droperidol may decrease the antihypertensive activities of Aliskiren. |
| Nicorandil | Droperidol may decrease the antihypertensive activities of Nicorandil. |
| Rauwolfia serpentina root | Droperidol may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Droperidol may decrease the antihypertensive activities of Enalaprilat. |
| Selexipag | Droperidol may decrease the antihypertensive activities of Selexipag. |
| Angiotensin 1-7 | Droperidol may decrease the antihypertensive activities of Angiotensin 1-7. |
| Imidapril | Droperidol may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Droperidol may decrease the antihypertensive activities of BQ-123. |
| Dihydralazine | Droperidol may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Droperidol may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Droperidol may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Droperidol may decrease the antihypertensive activities of Delapril. |
| Vincamine | Droperidol may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Droperidol may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Droperidol may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Droperidol may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Droperidol may decrease the antihypertensive activities of Endralazine. |
| Cadralazine | Droperidol may decrease the antihypertensive activities of Cadralazine. |
| Cyclopenthiazide | Droperidol may decrease the antihypertensive activities of Cyclopenthiazide. |
| Bietaserpine | Droperidol may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Droperidol may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Droperidol may decrease the antihypertensive activities of Methoserpidine. |
| Guanoclor | Droperidol may decrease the antihypertensive activities of Guanoclor. |
| Muzolimine | Droperidol may decrease the antihypertensive activities of Muzolimine. |
| Xipamide | Droperidol may decrease the antihypertensive activities of Xipamide. |
| Candesartan | Droperidol may decrease the antihypertensive activities of Candesartan. |
| Tocopherylquinone | Droperidol may decrease the antihypertensive activities of Tocopherylquinone. |
| Benazeprilat | Droperidol may decrease the antihypertensive activities of Benazeprilat. |
| Fosinoprilat | Droperidol may decrease the antihypertensive activities of Fosinoprilat. |
| Ramiprilat | Droperidol may decrease the antihypertensive activities of Ramiprilat. |
| Perindoprilat | Droperidol may decrease the antihypertensive activities of Perindoprilat. |
| Quinaprilat | Droperidol may decrease the antihypertensive activities of Quinaprilat. |
| Furosemide | Droperidol may decrease the antihypertensive activities of Furosemide. |
| Levamlodipine | Droperidol may decrease the antihypertensive activities of Levamlodipine. |
| Buthiazide | Droperidol may decrease the antihypertensive activities of Buthiazide. |
| Azilsartan medoxomil | Droperidol may decrease the antihypertensive activities of Azilsartan medoxomil. |
| Buprenorphine | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Droperidol. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Droperidol. |
| Botulinum toxin type B | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Botulinum toxin type B. |
| Botulinum toxin type A | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Botulinum toxin type A. |
| Baclofen | Baclofen may increase the central nervous system depressant (CNS depressant) activities of Droperidol. |
| Ethchlorvynol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Ethchlorvynol. |
| Succinylcholine | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Succinylcholine. |
| Eletriptan | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Eletriptan. |
| Enflurane | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Enflurane. |