Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants.
Nitric oxide (NO) should not be confused with nitrous oxide (N2O), a general anaesthetic, or with nitrogen dioxide (NO2) which is another poisonous air pollutant.
The nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity. It reacts with the ozone in air to form nitrogen dioxide, signalled by the appearance of the reddish-brown color.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Duloxetine | The risk or severity of orthostatic hypotension and syncope can be increased when Nitric Oxide is combined with Duloxetine. |
| Levodopa | The risk or severity of hypotension and orthostatic hypotension can be increased when Nitric Oxide is combined with Levodopa. |
| Risperidone | Nitric Oxide may increase the hypotensive activities of Risperidone. |
| Eliglustat | The metabolism of Eliglustat can be decreased when combined with Nitric Oxide. |
| Ibrutinib | The metabolism of Ibrutinib can be decreased when combined with Nitric Oxide. |
| Cilostazol | The metabolism of Cilostazol can be decreased when combined with Nitric Oxide. |
| Colchicine | The metabolism of Colchicine can be decreased when combined with Nitric Oxide. |
| Fentanyl | Nitric Oxide may decrease the excretion rate of Fentanyl which could result in a higher serum level. |
| Iloperidone | The metabolism of Iloperidone can be decreased when combined with Nitric Oxide. |
| Retapamulin | The metabolism of Retapamulin can be decreased when combined with Nitric Oxide. |
| Tofacitinib | The metabolism of Tofacitinib can be decreased when combined with Nitric Oxide. |
| Vardenafil | The metabolism of Vardenafil can be decreased when combined with Nitric Oxide. |
| Eszopiclone | The metabolism of Eszopiclone can be decreased when combined with Nitric Oxide. |
| Zopiclone | The metabolism of Zopiclone can be decreased when combined with Nitric Oxide. |
| Lovastatin | The metabolism of Lovastatin can be decreased when combined with Nitric Oxide. |
| Prilocaine | The risk or severity of methemoglobinemia can be increased when Nitric Oxide is combined with Prilocaine. |
| Zolmitriptan | The metabolism of Zolmitriptan can be decreased when combined with Nitric Oxide. |
| Alfuzosin | The metabolism of Alfuzosin can be decreased when combined with Nitric Oxide. |
| Alprazolam | The metabolism of Alprazolam can be decreased when combined with Nitric Oxide. |
| Warfarin | The serum concentration of Warfarin can be increased when it is combined with Nitric Oxide. |
| Acenocoumarol | The serum concentration of Acenocoumarol can be increased when it is combined with Nitric Oxide. |
| (R)-warfarin | The serum concentration of (R)-warfarin can be increased when it is combined with Nitric Oxide. |
| R,S-Warfarin alcohol | The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with Nitric Oxide. |
| S,R-Warfarin alcohol | The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with Nitric Oxide. |
| (S)-Warfarin | The serum concentration of (S)-Warfarin can be increased when it is combined with Nitric Oxide. |
| Midazolam | The serum concentration of Midazolam can be increased when it is combined with Nitric Oxide. |
| Tacrolimus | The serum concentration of Tacrolimus can be increased when it is combined with Nitric Oxide. |
| Atorvastatin | The metabolism of Atorvastatin can be decreased when combined with Nitric Oxide. |
| Nicorandil | Nicorandil may increase the hypotensive activities of Nitric Oxide. |
| Dapsone | The risk or severity of methemoglobinemia can be increased when Dapsone is combined with Nitric Oxide. |
| Linezolid | Linezolid may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Furazolidone | Furazolidone may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Tranylcypromine | Tranylcypromine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Phenelzine | Phenelzine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Minaprine | Minaprine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Selegiline | Selegiline may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Procarbazine | Procarbazine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Moclobemide | Moclobemide may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Isocarboxazid | Isocarboxazid may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Rasagiline | Rasagiline may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Pargyline | Pargyline may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Clorgiline | Clorgiline may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Iproniazid | Iproniazid may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Nialamide | Nialamide may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Safinamide | Safinamide may increase the orthostatic hypotensive activities of Nitric Oxide. |
| 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline | 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Methylene blue | Methylene blue may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Hydracarbazine | Hydracarbazine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Pirlindole | Pirlindole may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Toloxatone | Toloxatone may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Benmoxin | Benmoxin may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Mebanazine | Mebanazine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Octamoxin | Octamoxin may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Pheniprazine | Pheniprazine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Phenoxypropazine | Phenoxypropazine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Pivhydrazine | Pivhydrazine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Safrazine | Safrazine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Caroxazone | Caroxazone may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Harmaline | Harmaline may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Brofaromine | Brofaromine may increase the orthostatic hypotensive activities of Nitric Oxide. |
| Pentobarbital | Pentobarbital may increase the hypotensive activities of Nitric Oxide. |
| Secobarbital | Secobarbital may increase the hypotensive activities of Nitric Oxide. |
| Methohexital | Methohexital may increase the hypotensive activities of Nitric Oxide. |
| Thiopental | Thiopental may increase the hypotensive activities of Nitric Oxide. |
| Primidone | Primidone may increase the hypotensive activities of Nitric Oxide. |
| Methylphenobarbital | Methylphenobarbital may increase the hypotensive activities of Nitric Oxide. |
| Thiamylal | Thiamylal may increase the hypotensive activities of Nitric Oxide. |
| Amobarbital | Amobarbital may increase the hypotensive activities of Nitric Oxide. |
| Hexobarbital | Hexobarbital may increase the hypotensive activities of Nitric Oxide. |
| Barbital | Barbital may increase the hypotensive activities of Nitric Oxide. |
| Barbexaclone | Barbexaclone may increase the hypotensive activities of Nitric Oxide. |
| Butabarbital | Butabarbital may increase the hypotensive activities of Nitric Oxide. |
| Streptokinase | The risk or severity of adverse effects can be increased when Streptokinase is combined with Nitric Oxide. |
| Nabilone | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Nabilone. |
| Sotalol | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Sotalol. |
| Thioridazine | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Thioridazine. |
| Remifentanil | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Remifentanil. |
| Levosimendan | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Levosimendan. |
| Dipyridamole | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Dipyridamole. |
| Thalidomide | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Thalidomide. |
| Iloprost | Iloprost may increase the hypotensive activities of Nitric Oxide. |
| Papaverine | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Papaverine. |
| Amifostine | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Amifostine. |
| Desflurane | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Desflurane. |
| Carbetocin | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Carbetocin. |
| Nesiritide | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Nesiritide. |
| Azilsartan medoxomil | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Azilsartan medoxomil. |
| Obinutuzumab | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Obinutuzumab. |
| Isoxsuprine | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Isoxsuprine. |
| Dinutuximab | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Dinutuximab. |
| Nitrous acid | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Nitrous acid. |
| Fimasartan | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Fimasartan. |
| Pipamperone | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Pipamperone. |
| Valsartan | The risk or severity of adverse effects can be increased when Valsartan is combined with Nitric Oxide. |
| Ramipril | The risk or severity of adverse effects can be increased when Ramipril is combined with Nitric Oxide. |
| Esmolol | The risk or severity of adverse effects can be increased when Esmolol is combined with Nitric Oxide. |
| Olmesartan | The risk or severity of adverse effects can be increased when Olmesartan is combined with Nitric Oxide. |
| Atenolol | The risk or severity of adverse effects can be increased when Atenolol is combined with Nitric Oxide. |
| Minoxidil | The risk or severity of adverse effects can be increased when Minoxidil is combined with Nitric Oxide. |
| Prazosin | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Prazosin. |