Ampicillin

DB00415

small molecule approved vet_approved

Deskripsi

Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.

Struktur Molekul 2D

Berat 349.405
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Ampicillin is excreted largely unchanged in the urine.

Interaksi Makanan

1 Data
  • 1. Take on an empty stomach.

Interaksi Obat

869 Data
Methotrexate The excretion of Methotrexate can be decreased when combined with Ampicillin.
Atenolol The bioavailability of Atenolol can be decreased when combined with Ampicillin.
Doxycycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Doxycycline.
Lymecycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Lymecycline.
Clomocycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Clomocycline.
Tigecycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Tigecycline.
Oxytetracycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Oxytetracycline.
Demeclocycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Demeclocycline.
Tetracycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Tetracycline.
Metacycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Metacycline.
Minocycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Minocycline.
Rolitetracycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Rolitetracycline.
Sarecycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Sarecycline.
Eravacycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Eravacycline.
Omadacycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Omadacycline.
Penimepicycline The therapeutic efficacy of Ampicillin can be decreased when used in combination with Penimepicycline.
Allopurinol The risk of a hypersensitivity reaction to Ampicillin is increased when it is combined with Allopurinol.
Chloroquine The bioavailability of Ampicillin can be decreased when combined with Chloroquine.
Lanthanum carbonate The serum concentration of Ampicillin can be decreased when it is combined with Lanthanum carbonate.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Ampicillin.
Dicoumarol Ampicillin may increase the anticoagulant activities of Dicoumarol.
Phenindione Ampicillin may increase the anticoagulant activities of Phenindione.
Phenprocoumon Ampicillin may increase the anticoagulant activities of Phenprocoumon.
Acenocoumarol Ampicillin may increase the anticoagulant activities of Acenocoumarol.
4-hydroxycoumarin Ampicillin may increase the anticoagulant activities of 4-hydroxycoumarin.
Coumarin Ampicillin may increase the anticoagulant activities of Coumarin.
(R)-warfarin Ampicillin may increase the anticoagulant activities of (R)-warfarin.
Ethyl biscoumacetate Ampicillin may increase the anticoagulant activities of Ethyl biscoumacetate.
Fluindione Ampicillin may increase the anticoagulant activities of Fluindione.
Clorindione Ampicillin may increase the anticoagulant activities of Clorindione.
Diphenadione Ampicillin may increase the anticoagulant activities of Diphenadione.
Tioclomarol Ampicillin may increase the anticoagulant activities of Tioclomarol.
(S)-Warfarin Ampicillin may increase the anticoagulant activities of (S)-Warfarin.
Diethylstilbestrol The therapeutic efficacy of Diethylstilbestrol can be decreased when used in combination with Ampicillin.
Desogestrel The therapeutic efficacy of Desogestrel can be decreased when used in combination with Ampicillin.
Levonorgestrel The therapeutic efficacy of Levonorgestrel can be decreased when used in combination with Ampicillin.
Progesterone The therapeutic efficacy of Progesterone can be decreased when used in combination with Ampicillin.
Norethisterone The therapeutic efficacy of Norethisterone can be decreased when used in combination with Ampicillin.
Ethynodiol diacetate The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Ampicillin.
Mifepristone The therapeutic efficacy of Mifepristone can be decreased when used in combination with Ampicillin.
Norgestimate The therapeutic efficacy of Norgestimate can be decreased when used in combination with Ampicillin.
Ethinylestradiol The therapeutic efficacy of Ethinylestradiol can be decreased when used in combination with Ampicillin.
Mestranol The therapeutic efficacy of Mestranol can be decreased when used in combination with Ampicillin.
Octylphenoxy polyethoxyethanol The therapeutic efficacy of Octylphenoxy polyethoxyethanol can be decreased when used in combination with Ampicillin.
Cyproterone acetate The therapeutic efficacy of Cyproterone acetate can be decreased when used in combination with Ampicillin.
Trestolone The therapeutic efficacy of Trestolone can be decreased when used in combination with Ampicillin.
Norelgestromin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Ampicillin.
Gestodene The therapeutic efficacy of Gestodene can be decreased when used in combination with Ampicillin.
Hydroxyprogesterone caproate The therapeutic efficacy of Hydroxyprogesterone caproate can be decreased when used in combination with Ampicillin.
Ulipristal The therapeutic efficacy of Ulipristal can be decreased when used in combination with Ampicillin.
Norethynodrel The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Ampicillin.
Norgestrel The therapeutic efficacy of Norgestrel can be decreased when used in combination with Ampicillin.
Cloprostenol The therapeutic efficacy of Cloprostenol can be decreased when used in combination with Ampicillin.
Gestrinone The therapeutic efficacy of Gestrinone can be decreased when used in combination with Ampicillin.
Nomegestrol The therapeutic efficacy of Nomegestrol can be decreased when used in combination with Ampicillin.
Lynestrenol The therapeutic efficacy of Lynestrenol can be decreased when used in combination with Ampicillin.
Gossypol The therapeutic efficacy of Gossypol can be decreased when used in combination with Ampicillin.
Ormeloxifene The therapeutic efficacy of Ormeloxifene can be decreased when used in combination with Ampicillin.
Chlormadinone The therapeutic efficacy of Chlormadinone can be decreased when used in combination with Ampicillin.
Norgestrienone The therapeutic efficacy of Norgestrienone can be decreased when used in combination with Ampicillin.
Quingestanol The therapeutic efficacy of Quingestanol can be decreased when used in combination with Ampicillin.
Demegestone The therapeutic efficacy of Demegestone can be decreased when used in combination with Ampicillin.
Etynodiol The therapeutic efficacy of Etynodiol can be decreased when used in combination with Ampicillin.
Estradiol benzoate The therapeutic efficacy of Estradiol benzoate can be decreased when used in combination with Ampicillin.
Nomegestrol acetate The therapeutic efficacy of Nomegestrol acetate can be decreased when used in combination with Ampicillin.
Norethindrone enanthate The therapeutic efficacy of Norethindrone enanthate can be decreased when used in combination with Ampicillin.
Framycetin The serum concentration of Framycetin can be decreased when it is combined with Ampicillin.
Paromomycin The serum concentration of Paromomycin can be decreased when it is combined with Ampicillin.
Geneticin The serum concentration of Geneticin can be decreased when it is combined with Ampicillin.
Apramycin The serum concentration of Apramycin can be decreased when it is combined with Ampicillin.
Neamine The serum concentration of Neamine can be decreased when it is combined with Ampicillin.
Puromycin The serum concentration of Puromycin can be decreased when it is combined with Ampicillin.
Dihydrostreptomycin The serum concentration of Dihydrostreptomycin can be decreased when it is combined with Ampicillin.
Hygromycin B The serum concentration of Hygromycin B can be decreased when it is combined with Ampicillin.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Ampicillin.
Typhoid vaccine The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Ampicillin.
Acemetacin Acemetacin may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Cyclosporine Cyclosporine may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Icosapent Icosapent may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Cefotiam Cefotiam may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Mesalazine Mesalazine may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Cefmenoxime Cefmenoxime may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Cefmetazole Cefmetazole may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Pamidronic acid Pamidronic acid may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Tenofovir disoproxil Tenofovir disoproxil may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Indomethacin Indomethacin may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Cidofovir Cidofovir may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Cefpiramide Cefpiramide may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Ceftazidime Ceftazidime may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Loracarbef Loracarbef may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Cefalotin Cefalotin may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Nabumetone Nabumetone may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Ketorolac Ketorolac may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Tenoxicam Tenoxicam may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Celecoxib Celecoxib may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Cefotaxime Cefotaxime may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Tolmetin Tolmetin may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Foscarnet Foscarnet may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Rofecoxib Rofecoxib may decrease the excretion rate of Ampicillin which could result in a higher serum level.
Piroxicam Piroxicam may decrease the excretion rate of Ampicillin which could result in a higher serum level.

Target Protein

Penicillin-binding protein 2a pbp2a
Penicillin-binding protein 1b pbp1b
Penicillin-binding protein 3 pbp3
Penicillin-binding protein 1A pbpA
Penicillin-binding protein 2B penA
Solute carrier family 15 member 1 SLC15A1
Solute carrier family 15 member 2 SLC15A2
Angiopoietin-1 receptor TEK

Referensi & Sumber

Synthesis reference: Jean Bouchaudon, Pierre Le Roy, Mayer Naoum Messer, "Process for the preparation of ampicillin." U.S. Patent US3978078, issued December, 1974.

Contoh Produk & Brand

Produk: 353 • International brands: 9
Produk
  • Ampicillin
    Injection, powder, for solution • 1 g/1 • Intramuscular; Intravenous • US • Generic • Approved
  • Ampicillin
    Injection, powder, for solution • 250 mg/1 • Intramuscular; Intravenous • US • Generic • Approved
  • Ampicillin
    Injection, powder, for solution • 500 mg/1 • Intramuscular; Intravenous • US • Generic • Approved
  • Ampicillin
    Injection, powder, for solution • 1 g/1 • Intramuscular; Intravenous • US • Generic • Approved
  • Ampicillin
    Injection, powder, for solution • 2 g/1 • Intravenous • US • Generic • Approved
  • Ampicillin
    Injection, powder, for solution • 125 mg/1 • Intramuscular; Intravenous • US • Generic • Approved
  • Ampicillin
    Injection, powder, for solution • 250 mg/1 • Intramuscular; Intravenous • US • Generic • Approved
  • Ampicillin
    Injection, powder, for solution • 500 mg/1 • Intramuscular; Intravenous • US • Generic • Approved
Menampilkan 8 dari 353 produk.
International Brands
  • Austrapen — Lennon Healthcare
  • Binotal — Bayer
  • Penbritin — GlaxoSmithKline
  • Principen
  • Redicilin
  • Semicillin
  • Tokiocillin
  • Ultrabion
  • Viccillin — Meiji

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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