Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Pegvisomant | The risk or severity of hypoglycemia can be increased when Pegvisomant is combined with Acetohexamide. |
| Carbocisteine | The risk or severity of adverse effects can be increased when Acetohexamide is combined with Carbocisteine. |
| Chloramphenicol | The metabolism of Acetohexamide can be decreased when combined with Chloramphenicol. |
| Cimetidine | The serum concentration of Acetohexamide can be increased when it is combined with Cimetidine. |
| Fluconazole | The serum concentration of Acetohexamide can be increased when it is combined with Fluconazole. |
| Metreleptin | Metreleptin may increase the hypoglycemic activities of Acetohexamide. |
| Probenecid | The protein binding of Acetohexamide can be decreased when combined with Probenecid. |
| Ranitidine | The serum concentration of Acetohexamide can be increased when it is combined with Ranitidine. |
| Voriconazole | The serum concentration of Acetohexamide can be increased when it is combined with Voriconazole. |
| Clarithromycin | The serum concentration of Acetohexamide can be increased when it is combined with Clarithromycin. |
| Lipoic acid | The risk or severity of hypoglycemia can be increased when Lipoic acid is combined with Acetohexamide. |
| Rifampin | The serum concentration of Acetohexamide can be decreased when it is combined with Rifampicin. |
| Moxifloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Moxifloxacin. |
| Grepafloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Grepafloxacin. |
| Enoxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Enoxacin. |
| Pefloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Pefloxacin. |
| Ciprofloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Ciprofloxacin. |
| Trovafloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Trovafloxacin. |
| Nalidixic acid | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Nalidixic acid. |
| Rosoxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Rosoxacin. |
| Cinoxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Cinoxacin. |
| Lomefloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Lomefloxacin. |
| Gatifloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Gatifloxacin. |
| Norfloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Norfloxacin. |
| Levofloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Levofloxacin. |
| Gemifloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Gemifloxacin. |
| Ofloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Ofloxacin. |
| Sparfloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sparfloxacin. |
| Temafloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Temafloxacin. |
| Fleroxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Fleroxacin. |
| Technetium Tc-99m ciprofloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Technetium Tc-99m ciprofloxacin. |
| Garenoxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Garenoxacin. |
| Nemonoxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Nemonoxacin. |
| Flumequine | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Flumequine. |
| Enrofloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Enrofloxacin. |
| Orbifloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Orbifloxacin. |
| Sarafloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sarafloxacin. |
| Difloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Difloxacin. |
| Pazufloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Pazufloxacin. |
| Prulifloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Prulifloxacin. |
| Delafloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Delafloxacin. |
| Sitafloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sitafloxacin. |
| Oxolinic acid | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Oxolinic acid. |
| Rufloxacin | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Rufloxacin. |
| Pipemidic acid | The therapeutic efficacy of Acetohexamide can be increased when used in combination with Pipemidic acid. |
| Methyclothiazide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Methyclothiazide. |
| Chlorthalidone | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Chlorthalidone. |
| Bendroflumethiazide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Bendroflumethiazide. |
| Metolazone | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Metolazone. |
| Benzthiazide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Benzthiazide. |
| Hydroflumethiazide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Hydroflumethiazide. |
| Indapamide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Indapamide. |
| Chlorothiazide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Chlorothiazide. |
| Hydrochlorothiazide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Hydrochlorothiazide. |
| Trichlormethiazide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Trichlormethiazide. |
| Polythiazide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Polythiazide. |
| Quinethazone | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Quinethazone. |
| Cyclopenthiazide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Cyclopenthiazide. |
| Epitizide | The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Epitizide. |
| Esmolol | Esmolol may increase the hypoglycemic activities of Acetohexamide. |
| Landiolol | Landiolol may increase the hypoglycemic activities of Acetohexamide. |
| Ethanol | The risk or severity of adverse effects can be increased when Acetohexamide is combined with Ethanol. |
| Amitriptyline | Amitriptyline may decrease the hypoglycemic activities of Acetohexamide. |
| Protriptyline | Protriptyline may decrease the hypoglycemic activities of Acetohexamide. |
| Imipramine | Imipramine may decrease the hypoglycemic activities of Acetohexamide. |
| Nortriptyline | Nortriptyline may decrease the hypoglycemic activities of Acetohexamide. |
| Amoxapine | Amoxapine may decrease the hypoglycemic activities of Acetohexamide. |
| Desipramine | Desipramine may decrease the hypoglycemic activities of Acetohexamide. |
| Clomipramine | Clomipramine may decrease the hypoglycemic activities of Acetohexamide. |
| Amineptine | Amineptine may decrease the hypoglycemic activities of Acetohexamide. |
| Dimetacrine | Dimetacrine may decrease the hypoglycemic activities of Acetohexamide. |
| Butriptyline | Butriptyline may decrease the hypoglycemic activities of Acetohexamide. |
| Dosulepin | Dosulepin may decrease the hypoglycemic activities of Acetohexamide. |
| Tianeptine | Tianeptine may decrease the hypoglycemic activities of Acetohexamide. |
| Oxaprotiline | Oxaprotiline may decrease the hypoglycemic activities of Acetohexamide. |
| Opipramol | Opipramol may decrease the hypoglycemic activities of Acetohexamide. |
| Amitriptylinoxide | Amitriptylinoxide may decrease the hypoglycemic activities of Acetohexamide. |
| Dibenzepin | Dibenzepin may decrease the hypoglycemic activities of Acetohexamide. |
| Quinupramine | Quinupramine may decrease the hypoglycemic activities of Acetohexamide. |
| Melitracen | Melitracen may decrease the hypoglycemic activities of Acetohexamide. |
| Lofepramine | Lofepramine may decrease the hypoglycemic activities of Acetohexamide. |
| Iprindole | Iprindole may decrease the hypoglycemic activities of Acetohexamide. |
| Imipramine oxide | Imipramine oxide may decrease the hypoglycemic activities of Acetohexamide. |
| Doxepin | Doxepin may decrease the hypoglycemic activities of Acetohexamide. |
| Clofibrate | The risk or severity of hypoglycemia can be increased when Clofibrate is combined with Acetohexamide. |
| Fenofibrate | The risk or severity of hypoglycemia can be increased when Fenofibrate is combined with Acetohexamide. |
| Bezafibrate | The risk or severity of hypoglycemia can be increased when Bezafibrate is combined with Acetohexamide. |
| Etofibrate | The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Acetohexamide. |
| Ciprofibrate | The risk or severity of hypoglycemia can be increased when Ciprofibrate is combined with Acetohexamide. |
| Simfibrate | The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Acetohexamide. |
| Ronifibrate | The risk or severity of hypoglycemia can be increased when Ronifibrate is combined with Acetohexamide. |
| Aluminium clofibrate | The risk or severity of hypoglycemia can be increased when Aluminium clofibrate is combined with Acetohexamide. |
| Clofibride | The risk or severity of hypoglycemia can be increased when Clofibride is combined with Acetohexamide. |
| Fenofibric acid | The risk or severity of hypoglycemia can be increased when Fenofibric acid is combined with Acetohexamide. |
| Miconazole | The serum concentration of Acetohexamide can be increased when it is combined with Miconazole. |
| Phenindione | Acetohexamide may increase the anticoagulant activities of Phenindione. |
| Coumarin | Acetohexamide may increase the anticoagulant activities of Coumarin. |
| (R)-warfarin | Acetohexamide may increase the anticoagulant activities of (R)-warfarin. |
| Clorindione | Acetohexamide may increase the anticoagulant activities of Clorindione. |
| Diphenadione | Acetohexamide may increase the anticoagulant activities of Diphenadione. |