Peringatan Keamanan

Signs of an overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness.

Dexbrompheniramine

DB00405

small molecule approved

Deskripsi

Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.

Struktur Molekul 2D

Berat 319.239
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 25 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Antihistamines are well absorbed from the gastrointestinal tract after oral administration.

Metabolisme

Hepatic (cytochrome P-450 system), some renal.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Avoid alcohol. Taking with alcohol may increase drowsiness.

Interaksi Obat

957 Data
Buprenorphine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Dexbrompheniramine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Dexbrompheniramine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Dexbrompheniramine.
Hydrocodone Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Magnesium sulfate The therapeutic efficacy of Dexbrompheniramine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Dexbrompheniramine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Dexbrompheniramine.
Mirtazapine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Dexbrompheniramine.
Orphenadrine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Dexbrompheniramine.
Pramipexole Dexbrompheniramine may increase the sedative activities of Pramipexole.
Ropinirole Dexbrompheniramine may increase the sedative activities of Ropinirole.
Rotigotine Dexbrompheniramine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Dexbrompheniramine.
Sodium oxybate Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Dexbrompheniramine.
Thalidomide Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Benzylpenicilloyl polylysine Dexbrompheniramine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Betahistine The therapeutic efficacy of Betahistine can be decreased when used in combination with Dexbrompheniramine.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Dexbrompheniramine.
Ethanol Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Dexbrompheniramine.
Fluvoxamine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Fluvoxamine.
Duloxetine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Duloxetine.
Paroxetine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Nefazodone.
Zimelidine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Alaproclate.
Citalopram The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Citalopram.
Escitalopram The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Escitalopram.
Amphetamine Amphetamine may decrease the sedative activities of Dexbrompheniramine.
Phentermine Phentermine may decrease the sedative activities of Dexbrompheniramine.
Benzphetamine Benzphetamine may decrease the sedative activities of Dexbrompheniramine.
Diethylpropion Diethylpropion may decrease the sedative activities of Dexbrompheniramine.
Lisdexamfetamine Lisdexamfetamine may decrease the sedative activities of Dexbrompheniramine.
Mephentermine Mephentermine may decrease the sedative activities of Dexbrompheniramine.
MMDA MMDA may decrease the sedative activities of Dexbrompheniramine.
Midomafetamine Midomafetamine may decrease the sedative activities of Dexbrompheniramine.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the sedative activities of Dexbrompheniramine.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the sedative activities of Dexbrompheniramine.
Tenamfetamine Tenamfetamine may decrease the sedative activities of Dexbrompheniramine.
Chlorphentermine Chlorphentermine may decrease the sedative activities of Dexbrompheniramine.
Methylenedioxyethamphetamine Methylenedioxyethamphetamine may decrease the sedative activities of Dexbrompheniramine.
Dextroamphetamine Dextroamphetamine may decrease the sedative activities of Dexbrompheniramine.
Metamfetamine Metamfetamine may decrease the sedative activities of Dexbrompheniramine.
Iofetamine I-123 Iofetamine I-123 may decrease the sedative activities of Dexbrompheniramine.
Ritobegron Ritobegron may decrease the sedative activities of Dexbrompheniramine.
Mephedrone Mephedrone may decrease the sedative activities of Dexbrompheniramine.
Methoxyphenamine Methoxyphenamine may decrease the sedative activities of Dexbrompheniramine.
Gepefrine Gepefrine may decrease the sedative activities of Dexbrompheniramine.
2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine may decrease the sedative activities of Dexbrompheniramine.
Phendimetrazine Phendimetrazine may decrease the sedative activities of Dexbrompheniramine.
Benzatropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Dexbrompheniramine.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Dexbrompheniramine.
Buclizine The risk or severity of QTc prolongation can be increased when Buclizine is combined with Dexbrompheniramine.
Cyproheptadine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Cyproheptadine.
Imipramine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Imipramine.
Nortriptyline The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Nortriptyline.
Amoxapine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Amoxapine.
Nicardipine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Nicardipine.
Propiomazine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Propiomazine.
Maprotiline The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Maprotiline.
Tolterodine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Tolterodine.
Doxepin The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Doxepin.
Desipramine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Desipramine.
Solifenacin The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Solifenacin.
Pizotifen The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Pizotifen.
Trimebutine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Trimebutine.
Dosulepin The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Dosulepin.
Zopiclone The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Zopiclone.
Leuprolide The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Leuprolide.
Goserelin The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Goserelin.
Erythromycin The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Erythromycin.
Azithromycin The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Azithromycin.
Moxifloxacin The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Moxifloxacin.
Ranolazine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Ranolazine.
Sulfisoxazole The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Sulfisoxazole.
Diltiazem The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Diltiazem.
Nimodipine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Nimodipine.
Oxaliplatin The risk or severity of QTc prolongation can be increased when Oxaliplatin is combined with Dexbrompheniramine.
Ciprofloxacin The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Ciprofloxacin.
Fluorouracil The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Fluorouracil.
Perflutren The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Perflutren.
Cinnarizine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Cinnarizine.
Atropine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Atropine.

Target Protein

Histamine H1 receptor HRH1

Referensi & Sumber

Synthesis reference: Walter, L.A.; U.S. Patents 3,061,517; October 30, 1962; and 3,030,371; April 17, 1962; both assigned to Schering Corporation.

Contoh Produk & Brand

Produk: 49 • International brands: 2
Produk
  • Accu Tuss DM
    Liquid • - • Oral • US • OTC
  • Acticon
    Liquid • - • Oral • US • OTC
  • Acticon
    Tablet • - • Oral • US • OTC
  • Acticon
    Solution • - • Oral • US • OTC
  • Actidogesic
    Tablet • - • Oral • US • OTC
  • Actidogesic DF
    Tablet • - • Oral • US • OTC
  • Ala-hist Ir
    Tablet • 2 mg/1 • Oral • US • OTC
  • Ala-hist PE
    Tablet • - • Oral • US • OTC
Menampilkan 8 dari 49 produk.
International Brands
  • Disophrol — Schering
  • Drixoral — Schering

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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