May induce ventricular extrasystoles and short paroxysms of ventricular tachycardia, a sensation of fullness in the head and tingling of the extremities; LD50=1490mg/kg (orally in rat)
Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Valsartan | Phenylpropanolamine may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Phenylpropanolamine may decrease the antihypertensive activities of Ramipril. |
| Reserpine | Phenylpropanolamine may decrease the antihypertensive activities of Reserpine. |
| Remikiren | Phenylpropanolamine may decrease the antihypertensive activities of Remikiren. |
| Isradipine | Phenylpropanolamine may decrease the antihypertensive activities of Isradipine. |
| Olmesartan | Phenylpropanolamine may decrease the antihypertensive activities of Olmesartan. |
| Nitroprusside | Phenylpropanolamine may decrease the antihypertensive activities of Nitroprusside. |
| Diltiazem | Phenylpropanolamine may decrease the antihypertensive activities of Diltiazem. |
| Minoxidil | Phenylpropanolamine may decrease the antihypertensive activities of Minoxidil. |
| Treprostinil | Phenylpropanolamine may decrease the antihypertensive activities of Treprostinil. |
| Amlodipine | Phenylpropanolamine may decrease the antihypertensive activities of Amlodipine. |
| Nimodipine | Phenylpropanolamine may decrease the antihypertensive activities of Nimodipine. |
| Nisoldipine | Phenylpropanolamine may decrease the antihypertensive activities of Nisoldipine. |
| Fosinopril | Phenylpropanolamine may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Phenylpropanolamine may decrease the antihypertensive activities of Trandolapril. |
| Lercanidipine | Phenylpropanolamine may decrease the antihypertensive activities of Lercanidipine. |
| Benazepril | Phenylpropanolamine may decrease the antihypertensive activities of Benazepril. |
| Bosentan | Phenylpropanolamine may decrease the antihypertensive activities of Bosentan. |
| Enalapril | Phenylpropanolamine may decrease the antihypertensive activities of Enalapril. |
| Candoxatril | Phenylpropanolamine may decrease the antihypertensive activities of Candoxatril. |
| Mecamylamine | Phenylpropanolamine may decrease the antihypertensive activities of Mecamylamine. |
| Losartan | Phenylpropanolamine may decrease the antihypertensive activities of Losartan. |
| Moexipril | Phenylpropanolamine may decrease the antihypertensive activities of Moexipril. |
| Eplerenone | Phenylpropanolamine may decrease the antihypertensive activities of Eplerenone. |
| Lisinopril | Phenylpropanolamine may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Phenylpropanolamine may decrease the antihypertensive activities of Nitroglycerin. |
| Metyrosine | Phenylpropanolamine may decrease the antihypertensive activities of Metyrosine. |
| Cryptenamine | Phenylpropanolamine may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Phenylpropanolamine may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Phenylpropanolamine may decrease the antihypertensive activities of Candesartan cilexetil. |
| Fenoldopam | Phenylpropanolamine may decrease the antihypertensive activities of Fenoldopam. |
| Tadalafil | Phenylpropanolamine may decrease the antihypertensive activities of Tadalafil. |
| Eprosartan | Phenylpropanolamine may decrease the antihypertensive activities of Eprosartan. |
| Quinapril | Phenylpropanolamine may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Phenylpropanolamine may decrease the antihypertensive activities of Telmisartan. |
| Methyldopa | Phenylpropanolamine may decrease the antihypertensive activities of Methyldopa. |
| Irbesartan | Phenylpropanolamine may decrease the antihypertensive activities of Irbesartan. |
| Nitrendipine | Phenylpropanolamine may decrease the antihypertensive activities of Nitrendipine. |
| Deserpidine | Phenylpropanolamine may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Phenylpropanolamine may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Phenylpropanolamine may decrease the antihypertensive activities of Trimethaphan. |
| Diazoxide | Phenylpropanolamine may decrease the antihypertensive activities of Diazoxide. |
| Captopril | Phenylpropanolamine may decrease the antihypertensive activities of Captopril. |
| Epoprostenol | Phenylpropanolamine may decrease the antihypertensive activities of Epoprostenol. |
| Bepridil | Phenylpropanolamine may decrease the antihypertensive activities of Bepridil. |
| Hydralazine | Phenylpropanolamine may decrease the antihypertensive activities of Hydralazine. |
| Cilazapril | Phenylpropanolamine may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Phenylpropanolamine may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Phenylpropanolamine may decrease the antihypertensive activities of Spirapril. |
| Mibefradil | Phenylpropanolamine may decrease the antihypertensive activities of Mibefradil. |
| Tienilic acid | Phenylpropanolamine may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Phenylpropanolamine may decrease the antihypertensive activities of Debrisoquine. |
| Sitaxentan | Phenylpropanolamine may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Phenylpropanolamine may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Phenylpropanolamine may decrease the antihypertensive activities of Diethylnorspermine. |
| Nilvadipine | Phenylpropanolamine may decrease the antihypertensive activities of Nilvadipine. |
| Pinacidil | Phenylpropanolamine may decrease the antihypertensive activities of Pinacidil. |
| Temocapril | Phenylpropanolamine may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Phenylpropanolamine may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Phenylpropanolamine may decrease the antihypertensive activities of Macitentan. |
| Hexamethonium | Phenylpropanolamine may decrease the antihypertensive activities of Hexamethonium. |
| Aliskiren | Phenylpropanolamine may decrease the antihypertensive activities of Aliskiren. |
| Nicorandil | Phenylpropanolamine may decrease the antihypertensive activities of Nicorandil. |
| Efonidipine | Phenylpropanolamine may decrease the antihypertensive activities of Efonidipine. |
| Lacidipine | Phenylpropanolamine may decrease the antihypertensive activities of Lacidipine. |
| Manidipine | Phenylpropanolamine may decrease the antihypertensive activities of Manidipine. |
| Rauwolfia serpentina root | Phenylpropanolamine may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Phenylpropanolamine may decrease the antihypertensive activities of Enalaprilat. |
| Selexipag | Phenylpropanolamine may decrease the antihypertensive activities of Selexipag. |
| Angiotensin 1-7 | Phenylpropanolamine may decrease the antihypertensive activities of Angiotensin 1-7. |
| Imidapril | Phenylpropanolamine may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Phenylpropanolamine may decrease the antihypertensive activities of BQ-123. |
| Tetrahydropalmatine | Phenylpropanolamine may decrease the antihypertensive activities of Tetrahydropalmatine. |
| Cicletanine | Phenylpropanolamine may decrease the antihypertensive activities of Cicletanine. |
| Dihydralazine | Phenylpropanolamine may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Phenylpropanolamine may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Phenylpropanolamine may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Phenylpropanolamine may decrease the antihypertensive activities of Delapril. |
| Vincamine | Phenylpropanolamine may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Phenylpropanolamine may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Phenylpropanolamine may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Phenylpropanolamine may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Phenylpropanolamine may decrease the antihypertensive activities of Endralazine. |
| Cadralazine | Phenylpropanolamine may decrease the antihypertensive activities of Cadralazine. |
| Bietaserpine | Phenylpropanolamine may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Phenylpropanolamine may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Phenylpropanolamine may decrease the antihypertensive activities of Methoserpidine. |
| Guanoclor | Phenylpropanolamine may decrease the antihypertensive activities of Guanoclor. |
| Muzolimine | Phenylpropanolamine may decrease the antihypertensive activities of Muzolimine. |
| Xipamide | Phenylpropanolamine may decrease the antihypertensive activities of Xipamide. |
| Candesartan | Phenylpropanolamine may decrease the antihypertensive activities of Candesartan. |
| Dexniguldipine | Phenylpropanolamine may decrease the antihypertensive activities of Dexniguldipine. |
| Tocopherylquinone | Phenylpropanolamine may decrease the antihypertensive activities of Tocopherylquinone. |
| Benazeprilat | Phenylpropanolamine may decrease the antihypertensive activities of Benazeprilat. |
| Fosinoprilat | Phenylpropanolamine may decrease the antihypertensive activities of Fosinoprilat. |
| Ramiprilat | Phenylpropanolamine may decrease the antihypertensive activities of Ramiprilat. |
| Perindoprilat | Phenylpropanolamine may decrease the antihypertensive activities of Perindoprilat. |
| Quinaprilat | Phenylpropanolamine may decrease the antihypertensive activities of Quinaprilat. |
| Felodipine | Phenylpropanolamine may decrease the antihypertensive activities of Felodipine. |
| Levamlodipine | Phenylpropanolamine may decrease the antihypertensive activities of Levamlodipine. |