Manifestations of acute overdosage of TORECAN (thiethylperazine) can be expected to reflect the CNS effects of the drug and include extrapyramidal symptoms (E.P.S), confusion and convulsions with reduced or absent reflexes, respiratory depression and hypotension.
A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Buprenorphine | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Thiethylperazine. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Thiethylperazine. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Thiethylperazine. |
| Hydrocodone | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Thiethylperazine. |
| Magnesium sulfate | The therapeutic efficacy of Thiethylperazine can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Thiethylperazine. |
| Mirtazapine | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Thiethylperazine. |
| Orphenadrine | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Thiethylperazine. |
| Rotigotine | Thiethylperazine may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Thiethylperazine. |
| Sodium oxybate | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Thiethylperazine. |
| Thalidomide | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Amisulpride | Thiethylperazine may increase the antipsychotic activities of Amisulpride. |
| Methylphenidate | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Methylphenidate. |
| Dexmethylphenidate | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Dexmethylphenidate. |
| Metoclopramide | The risk or severity of adverse effects can be increased when Metoclopramide is combined with Thiethylperazine. |
| Quinagolide | The therapeutic efficacy of Quinagolide can be decreased when used in combination with Thiethylperazine. |
| Sulpiride | Thiethylperazine may increase the antipsychotic activities of Sulpiride. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Thiethylperazine. |
| Lithium hydroxide | Lithium hydroxide may increase the neurotoxic activities of Thiethylperazine. |
| Lithium citrate | Lithium citrate may increase the neurotoxic activities of Thiethylperazine. |
| Mequitazine | Thiethylperazine may increase the arrhythmogenic activities of Mequitazine. |
| Thiopental | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Thiopental. |
| Metyrosine | The risk or severity of extrapyramidal symptoms and CNS depression can be increased when Metyrosine is combined with Thiethylperazine. |
| Ethanol | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Thiethylperazine. |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Fluvoxamine. |
| Citalopram | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Citalopram. |
| Duloxetine | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Duloxetine. |
| Trazodone | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Trazodone. |
| Paroxetine | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Paroxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Nefazodone. |
| Escitalopram | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Escitalopram. |
| Zimelidine | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Dapoxetine. |
| Milnacipran | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Milnacipran. |
| Desvenlafaxine | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Desvenlafaxine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Seproxetine. |
| Levomilnacipran | The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Thiethylperazine. |
| Indalpine | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Indalpine. |
| Ritanserin | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Ritanserin. |
| Alaproclate | The risk or severity of adverse effects can be increased when Thiethylperazine is combined with Alaproclate. |
| Esmolol | The serum concentration of Esmolol can be increased when it is combined with Thiethylperazine. |
| Betaxolol | The serum concentration of Betaxolol can be increased when it is combined with Thiethylperazine. |
| Metoprolol | The serum concentration of Metoprolol can be increased when it is combined with Thiethylperazine. |
| Atenolol | The serum concentration of Atenolol can be increased when it is combined with Thiethylperazine. |
| Timolol | The serum concentration of Timolol can be increased when it is combined with Thiethylperazine. |
| Sotalol | The serum concentration of Sotalol can be increased when it is combined with Thiethylperazine. |
| Propranolol | The serum concentration of Propranolol can be increased when it is combined with Thiethylperazine. |
| Labetalol | The serum concentration of Labetalol can be increased when it is combined with Thiethylperazine. |
| Bisoprolol | The serum concentration of Bisoprolol can be increased when it is combined with Thiethylperazine. |
| Alprenolol | The serum concentration of Alprenolol can be increased when it is combined with Thiethylperazine. |
| Pindolol | The serum concentration of Pindolol can be increased when it is combined with Thiethylperazine. |
| Carvedilol | The serum concentration of Carvedilol can be increased when it is combined with Thiethylperazine. |
| Propafenone | The serum concentration of Propafenone can be increased when it is combined with Thiethylperazine. |
| Acebutolol | The serum concentration of Acebutolol can be increased when it is combined with Thiethylperazine. |
| Nadolol | The serum concentration of Nadolol can be increased when it is combined with Thiethylperazine. |
| Bevantolol | The serum concentration of Bevantolol can be increased when it is combined with Thiethylperazine. |
| Practolol | The serum concentration of Practolol can be increased when it is combined with Thiethylperazine. |
| Penbutolol | The serum concentration of Penbutolol can be increased when it is combined with Thiethylperazine. |
| Oxprenolol | The serum concentration of Oxprenolol can be increased when it is combined with Thiethylperazine. |
| Dexpropranolol | The serum concentration of Dexpropranolol can be increased when it is combined with Thiethylperazine. |
| Celiprolol | The serum concentration of Celiprolol can be increased when it is combined with Thiethylperazine. |
| Nebivolol | The serum concentration of Nebivolol can be increased when it is combined with Thiethylperazine. |
| Bufuralol | The serum concentration of Bufuralol can be increased when it is combined with Thiethylperazine. |
| Bopindolol | The serum concentration of Bopindolol can be increased when it is combined with Thiethylperazine. |
| Bupranolol | The serum concentration of Bupranolol can be increased when it is combined with Thiethylperazine. |
| Indenolol | The serum concentration of Indenolol can be increased when it is combined with Thiethylperazine. |
| Arotinolol | The serum concentration of Arotinolol can be increased when it is combined with Thiethylperazine. |
| Levobetaxolol | The serum concentration of Levobetaxolol can be increased when it is combined with Thiethylperazine. |
| Talinolol | The serum concentration of Talinolol can be increased when it is combined with Thiethylperazine. |
| Anisodamine | The serum concentration of Anisodamine can be increased when it is combined with Thiethylperazine. |
| Bucindolol | The serum concentration of Bucindolol can be increased when it is combined with Thiethylperazine. |
| Esatenolol | The serum concentration of Esatenolol can be increased when it is combined with Thiethylperazine. |
| Cloranolol | The serum concentration of Cloranolol can be increased when it is combined with Thiethylperazine. |
| Mepindolol | The serum concentration of Mepindolol can be increased when it is combined with Thiethylperazine. |
| Epanolol | The serum concentration of Epanolol can be increased when it is combined with Thiethylperazine. |
| Tertatolol | The serum concentration of Tertatolol can be increased when it is combined with Thiethylperazine. |
| Landiolol | The serum concentration of Landiolol can be increased when it is combined with Thiethylperazine. |
| Morphine | The risk or severity of hypotension and CNS depression can be increased when Thiethylperazine is combined with Morphine. |
| Hydromorphone | The risk or severity of hypotension and CNS depression can be increased when Thiethylperazine is combined with Hydromorphone. |
| Oxycodone | The risk or severity of hypotension and CNS depression can be increased when Thiethylperazine is combined with Oxycodone. |
| Butorphanol | The risk or severity of hypotension and CNS depression can be increased when Thiethylperazine is combined with Butorphanol. |
| Dextropropoxyphene | The risk or severity of hypotension and CNS depression can be increased when Thiethylperazine is combined with Dextropropoxyphene. |
| Pentazocine | The risk or severity of hypotension and CNS depression can be increased when Thiethylperazine is combined with Pentazocine. |
| Naltrexone | The risk or severity of hypotension and CNS depression can be increased when Thiethylperazine is combined with Naltrexone. |
| Sufentanil | The risk or severity of hypotension and CNS depression can be increased when Thiethylperazine is combined with Sufentanil. |
| Alfentanil | The risk or severity of hypotension and CNS depression can be increased when Thiethylperazine is combined with Alfentanil. |