Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypokalemia.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Nicotine | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Nicotine. |
| Mecamylamine | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Mecamylamine. |
| Pentolinium | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Pentolinium. |
| Trimethaphan | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Trimethaphan. |
| Hexamethonium | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Hexamethonium. |
| Cyclopentamine | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Cyclopentamine. |
| Flecainide | The excretion of Flecainide can be decreased when combined with Ethoxzolamide. |
| Memantine | The excretion of Memantine can be decreased when combined with Ethoxzolamide. |
| Quinine | The excretion of Quinine can be decreased when combined with Ethoxzolamide. |
| Quinidine | The excretion of Quinidine can be decreased when combined with Ethoxzolamide. |
| Methotrexate | The protein binding of Methotrexate can be increased when combined with Ethoxzolamide. |
| Lithium hydroxide | The excretion of Lithium hydroxide can be increased when combined with Ethoxzolamide. |
| Lithium citrate | The excretion of Lithium citrate can be increased when combined with Ethoxzolamide. |
| Metformin | The risk or severity of lactic acidosis can be increased when Ethoxzolamide is combined with Metformin. |
| Dexketoprofen | The risk or severity of adverse effects can be increased when Dexketoprofen is combined with Ethoxzolamide. |
| Ketoprofen | The risk or severity of adverse effects can be increased when Ketoprofen is combined with Ethoxzolamide. |
| Methenamine | The serum concentration of the active metabolites of Methenamine can be reduced when Methenamine is used in combination with Ethoxzolamide resulting in a loss in efficacy. |
| Cyclosporine | The risk or severity of renal failure can be increased when Ethoxzolamide is combined with Cyclosporine. |
| Triethylenetetramine | The excretion of Triethylenetetramine can be increased when combined with Ethoxzolamide. |
| Aminosalicylic acid | The risk or severity of adverse effects can be increased when Aminosalicylic acid is combined with Ethoxzolamide. |
| Mesalazine | The risk or severity of adverse effects can be increased when Mesalazine is combined with Ethoxzolamide. |
| Sulfasalazine | The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Ethoxzolamide. |
| Diflunisal | The risk or severity of adverse effects can be increased when Diflunisal is combined with Ethoxzolamide. |
| Salicylic acid | The risk or severity of adverse effects can be increased when Salicylic acid is combined with Ethoxzolamide. |
| Balsalazide | The risk or severity of adverse effects can be increased when Balsalazide is combined with Ethoxzolamide. |
| Olsalazine | The risk or severity of adverse effects can be increased when Olsalazine is combined with Ethoxzolamide. |
| Bismuth subsalicylate | The risk or severity of adverse effects can be increased when Bismuth subsalicylate is combined with Ethoxzolamide. |
| Dersalazine | The risk or severity of adverse effects can be increased when Dersalazine is combined with Ethoxzolamide. |
| Phenyl aminosalicylate | The risk or severity of adverse effects can be increased when Phenyl aminosalicylate is combined with Ethoxzolamide. |
| Methyl salicylate | The risk or severity of adverse effects can be increased when Methyl salicylate is combined with Ethoxzolamide. |
| Nitroaspirin | The risk or severity of adverse effects can be increased when Nitroaspirin is combined with Ethoxzolamide. |
| Aloxiprin | The risk or severity of adverse effects can be increased when Aloxiprin is combined with Ethoxzolamide. |
| Guacetisal | The risk or severity of adverse effects can be increased when Guacetisal is combined with Ethoxzolamide. |
| Carbaspirin calcium | The risk or severity of adverse effects can be increased when Carbaspirin calcium is combined with Ethoxzolamide. |
| Choline salicylate | The risk or severity of adverse effects can be increased when Choline salicylate is combined with Ethoxzolamide. |
| Thiosalicylic acid | The risk or severity of adverse effects can be increased when Thiosalicylic acid is combined with Ethoxzolamide. |
| Phenytoin | The risk or severity of osteomalacia can be increased when Ethoxzolamide is combined with Phenytoin. |
| Fosphenytoin | The risk or severity of osteomalacia can be increased when Ethoxzolamide is combined with Fosphenytoin. |
| Methazolamide | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Methazolamide. |
| Acetazolamide | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Acetazolamide. |
| Zonisamide | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Zonisamide. |
| Diclofenamide | The risk or severity of adverse effects can be increased when Ethoxzolamide is combined with Diclofenamide. |
| Amphetamine | Ethoxzolamide may decrease the excretion rate of Amphetamine which could result in a higher serum level. |
| Phentermine | Ethoxzolamide may decrease the excretion rate of Phentermine which could result in a higher serum level. |
| Pseudoephedrine | Ethoxzolamide may decrease the excretion rate of Pseudoephedrine which could result in a higher serum level. |
| Benzphetamine | Ethoxzolamide may decrease the excretion rate of Benzphetamine which could result in a higher serum level. |
| Diethylpropion | Ethoxzolamide may decrease the excretion rate of Diethylpropion which could result in a higher serum level. |
| Lisdexamfetamine | Ethoxzolamide may decrease the excretion rate of Lisdexamfetamine which could result in a higher serum level. |
| Mephentermine | Ethoxzolamide may decrease the excretion rate of Mephentermine which could result in a higher serum level. |
| MMDA | Ethoxzolamide may decrease the excretion rate of MMDA which could result in a higher serum level. |
| Midomafetamine | Ethoxzolamide may decrease the excretion rate of Midomafetamine which could result in a higher serum level. |
| 2,5-Dimethoxy-4-ethylamphetamine | Ethoxzolamide may decrease the excretion rate of 2,5-Dimethoxy-4-ethylamphetamine which could result in a higher serum level. |
| 4-Bromo-2,5-dimethoxyamphetamine | Ethoxzolamide may decrease the excretion rate of 4-Bromo-2,5-dimethoxyamphetamine which could result in a higher serum level. |
| Tenamfetamine | Ethoxzolamide may decrease the excretion rate of Tenamfetamine which could result in a higher serum level. |
| Chlorphentermine | Ethoxzolamide may decrease the excretion rate of Chlorphentermine which could result in a higher serum level. |
| Methylenedioxyethamphetamine | Ethoxzolamide may decrease the excretion rate of Methylenedioxyethamphetamine which could result in a higher serum level. |
| Dextroamphetamine | Ethoxzolamide may decrease the excretion rate of Dextroamphetamine which could result in a higher serum level. |
| Metamfetamine | Ethoxzolamide may decrease the excretion rate of Metamfetamine which could result in a higher serum level. |
| Iofetamine I-123 | Ethoxzolamide may decrease the excretion rate of Iofetamine I-123 which could result in a higher serum level. |
| Ritobegron | Ethoxzolamide may decrease the excretion rate of Ritobegron which could result in a higher serum level. |
| Mephedrone | Ethoxzolamide may decrease the excretion rate of Mephedrone which could result in a higher serum level. |
| Methoxyphenamine | Ethoxzolamide may decrease the excretion rate of Methoxyphenamine which could result in a higher serum level. |
| Gepefrine | Ethoxzolamide may decrease the excretion rate of Gepefrine which could result in a higher serum level. |
| 2,5-Dimethoxy-4-ethylthioamphetamine | Ethoxzolamide may decrease the excretion rate of 2,5-Dimethoxy-4-ethylthioamphetamine which could result in a higher serum level. |
| Phendimetrazine | Ethoxzolamide may decrease the excretion rate of Phendimetrazine which could result in a higher serum level. |
| Sodium phosphate, monobasic | Ethoxzolamide may increase the nephrotoxic activities of Sodium phosphate, monobasic. |
| Acemetacin | The therapeutic efficacy of Ethoxzolamide can be decreased when used in combination with Acemetacin. |
| Lactulose | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Lactulose. |
| Magnesium sulfate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Magnesium sulfate. |
| Mannitol | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Mannitol. |
| Lubiprostone | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Lubiprostone. |
| Tegaserod | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Tegaserod. |
| Magnesium oxide | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Magnesium oxide. |
| Magnesium cation | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Magnesium cation. |
| Sorbitol | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Sorbitol. |
| Dantron | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Dantron. |
| Oxyphenisatin | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Oxyphenisatin. |
| Phenolphthalein | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Phenolphthalein. |
| Prucalopride | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Prucalopride. |
| Emodin | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Emodin. |
| Linaclotide | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Linaclotide. |
| Bisacodyl | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Bisacodyl. |
| Magnesium hydroxide | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Magnesium hydroxide. |
| Bisoxatin | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Bisoxatin. |
| Picosulfuric acid | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Picosulfuric acid. |
| Magnesium trisilicate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Magnesium trisilicate. |
| Polyethylene glycol | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Polyethylene glycol. |
| Polycarbophil | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Polycarbophil. |
| Magnesium acetate tetrahydrate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Magnesium acetate tetrahydrate. |
| Monopotassium phosphate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Monopotassium phosphate. |
| Dipotassium phosphate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Dipotassium phosphate. |
| Glycerin | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Glycerin. |
| Sodium sulfate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Sodium sulfate. |
| Magnesium carbonate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Magnesium carbonate. |
| Potassium lactate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Potassium lactate. |
| Sodium fluorophosphate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Sodium fluorophosphate. |
| Mineral oil | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Mineral oil. |
| Carboxymethylcellulose | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Carboxymethylcellulose. |
| Docusate | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Docusate. |
| Plantago seed | The risk or severity of dehydration can be increased when Ethoxzolamide is combined with Plantago seed. |