Acute overdose in animals results in CNS toxicity; notably, CNS depression, rapid gasping breathing, and convulsions. The intravenous median lethal dose in the rat was more than 50 mg/kg which is, on a mg/m2 basis, at least 250 times the maximum recommended human dose.
Ibutilide is a Class III antiarrhythmic agent available in intravenous formulations. It is indicated for the conversion of acute atrial flutter and recent onset atrial fibrillation to normal sinus rhythm (NSR).
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Fingolimod | Fingolimod may increase the arrhythmogenic activities of Ibutilide. |
| Lidocaine | Lidocaine may increase the arrhythmogenic activities of Ibutilide. |
| Atenolol | Ibutilide may increase the arrhythmogenic activities of Atenolol. |
| Mexiletine | Ibutilide may increase the arrhythmogenic activities of Mexiletine. |
| Acetyldigitoxin | Ibutilide may increase the arrhythmogenic activities of Acetyldigitoxin. |
| Carteolol | Ibutilide may increase the arrhythmogenic activities of Carteolol. |
| Lercanidipine | Ibutilide may increase the arrhythmogenic activities of Lercanidipine. |
| Magnesium sulfate | Ibutilide may increase the arrhythmogenic activities of Magnesium sulfate. |
| Alprenolol | Ibutilide may increase the arrhythmogenic activities of Alprenolol. |
| Tocainide | Ibutilide may increase the arrhythmogenic activities of Tocainide. |
| Deslanoside | Ibutilide may increase the arrhythmogenic activities of Deslanoside. |
| Carvedilol | Ibutilide may increase the arrhythmogenic activities of Carvedilol. |
| Metipranolol | Ibutilide may increase the arrhythmogenic activities of Metipranolol. |
| Practolol | Ibutilide may increase the arrhythmogenic activities of Practolol. |
| Aprindine | Ibutilide may increase the arrhythmogenic activities of Aprindine. |
| Dexpropranolol | Ibutilide may increase the arrhythmogenic activities of Dexpropranolol. |
| Cyclandelate | Ibutilide may increase the arrhythmogenic activities of Cyclandelate. |
| Flunarizine | Ibutilide may increase the arrhythmogenic activities of Flunarizine. |
| Nebivolol | Ibutilide may increase the arrhythmogenic activities of Nebivolol. |
| Seletracetam | Ibutilide may increase the arrhythmogenic activities of Seletracetam. |
| Nylidrin | Ibutilide may increase the arrhythmogenic activities of Nylidrin. |
| Dotarizine | Ibutilide may increase the arrhythmogenic activities of Dotarizine. |
| Xylometazoline | Ibutilide may increase the arrhythmogenic activities of Xylometazoline. |
| Sparteine | Ibutilide may increase the arrhythmogenic activities of Sparteine. |
| Tranilast | Ibutilide may increase the arrhythmogenic activities of Tranilast. |
| Fasudil | Ibutilide may increase the arrhythmogenic activities of Fasudil. |
| Agmatine | Ibutilide may increase the arrhythmogenic activities of Agmatine. |
| Barnidipine | Ibutilide may increase the arrhythmogenic activities of Barnidipine. |
| Azelnidipine | Ibutilide may increase the arrhythmogenic activities of Azelnidipine. |
| Cilnidipine | Ibutilide may increase the arrhythmogenic activities of Cilnidipine. |
| Darodipine | Ibutilide may increase the arrhythmogenic activities of Darodipine. |
| Manidipine | Ibutilide may increase the arrhythmogenic activities of Manidipine. |
| Niludipine | Ibutilide may increase the arrhythmogenic activities of Niludipine. |
| Carboxyamidotriazole | Ibutilide may increase the arrhythmogenic activities of Carboxyamidotriazole. |
| Naftopidil | Ibutilide may increase the arrhythmogenic activities of Naftopidil. |
| Vinpocetine | Ibutilide may increase the arrhythmogenic activities of Vinpocetine. |
| Landiolol | Ibutilide may increase the arrhythmogenic activities of Landiolol. |
| Cymarin | Ibutilide may increase the arrhythmogenic activities of Cymarin. |
| Metildigoxin | Ibutilide may increase the arrhythmogenic activities of Metildigoxin. |
| Tiracizine | Ibutilide may increase the arrhythmogenic activities of Tiracizine. |
| Ethacizine | Ibutilide may increase the arrhythmogenic activities of Ethacizine. |
| Hydroquinine | Ibutilide may increase the arrhythmogenic activities of Hydroquinine. |
| Bioallethrin | Ibutilide may increase the arrhythmogenic activities of Bioallethrin. |
| Tertatolol | Ibutilide may increase the arrhythmogenic activities of Tertatolol. |
| Caroverine | Ibutilide may increase the arrhythmogenic activities of Caroverine. |
| Fosfructose | Ibutilide may increase the arrhythmogenic activities of Fosfructose. |
| WIN 55212-2 | Ibutilide may increase the arrhythmogenic activities of WIN 55212-2. |
| Fish oil | Ibutilide may increase the arrhythmogenic activities of Fish oil. |
| Emopamil | Ibutilide may increase the arrhythmogenic activities of Emopamil. |
| Lomerizine | Ibutilide may increase the arrhythmogenic activities of Lomerizine. |
| Tetrandrine | Ibutilide may increase the arrhythmogenic activities of Tetrandrine. |
| Dexniguldipine | Ibutilide may increase the arrhythmogenic activities of Dexniguldipine. |
| Fosinoprilat | Ibutilide may increase the arrhythmogenic activities of Fosinoprilat. |
| Hydroquinidine | Ibutilide may increase the arrhythmogenic activities of Hydroquinidine. |
| SOR-C13 | Ibutilide may increase the arrhythmogenic activities of SOR-C13. |
| Betaxolol | Betaxolol may increase the arrhythmogenic activities of Ibutilide. |
| Diltiazem | Ibutilide may increase the arrhythmogenic activities of Diltiazem. |
| Nimodipine | Ibutilide may increase the arrhythmogenic activities of Nimodipine. |
| Cinnarizine | Ibutilide may increase the arrhythmogenic activities of Cinnarizine. |
| Propranolol | Ibutilide may increase the arrhythmogenic activities of Propranolol. |
| Atropine | Ibutilide may increase the arrhythmogenic activities of Atropine. |
| Adenosine | Ibutilide may increase the arrhythmogenic activities of Adenosine. |
| Loperamide | Ibutilide may increase the arrhythmogenic activities of Loperamide. |
| Levosimendan | Ibutilide may increase the arrhythmogenic activities of Levosimendan. |
| Nifedipine | Ibutilide may increase the arrhythmogenic activities of Nifedipine. |
| Propafenone | Ibutilide may increase the arrhythmogenic activities of Propafenone. |
| Acebutolol | Ibutilide may increase the arrhythmogenic activities of Acebutolol. |
| Flecainide | Ibutilide may increase the arrhythmogenic activities of Flecainide. |
| Mibefradil | Ibutilide may increase the arrhythmogenic activities of Mibefradil. |
| Oxprenolol | Ibutilide may increase the arrhythmogenic activities of Oxprenolol. |
| Prenylamine | Ibutilide may increase the arrhythmogenic activities of Prenylamine. |
| Fluspirilene | Ibutilide may increase the arrhythmogenic activities of Fluspirilene. |
| Azimilide | Ibutilide may increase the arrhythmogenic activities of Azimilide. |
| Tedisamil | Ibutilide may increase the arrhythmogenic activities of Tedisamil. |
| Nilvadipine | Ibutilide may increase the arrhythmogenic activities of Nilvadipine. |
| Fendiline | Ibutilide may increase the arrhythmogenic activities of Fendiline. |
| Eperisone | Ibutilide may increase the arrhythmogenic activities of Eperisone. |
| Melperone | Ibutilide may increase the arrhythmogenic activities of Melperone. |
| Benidipine | Ibutilide may increase the arrhythmogenic activities of Benidipine. |
| Simendan | Ibutilide may increase the arrhythmogenic activities of Simendan. |
| Otilonium | Ibutilide may increase the arrhythmogenic activities of Otilonium. |
| Nizofenone | Ibutilide may increase the arrhythmogenic activities of Nizofenone. |
| Bunaftine | Ibutilide may increase the arrhythmogenic activities of Bunaftine. |
| Lorcainide | Ibutilide may increase the arrhythmogenic activities of Lorcainide. |
| Penfluridol | Ibutilide may increase the arrhythmogenic activities of Penfluridol. |
| Dexverapamil | Ibutilide may increase the arrhythmogenic activities of Dexverapamil. |
| Esmolol | Esmolol may increase the arrhythmogenic activities of Ibutilide. |
| Isradipine | Isradipine may increase the arrhythmogenic activities of Ibutilide. |
| Trimethadione | Ibutilide may increase the arrhythmogenic activities of Trimethadione. |
| Timolol | Ibutilide may increase the arrhythmogenic activities of Timolol. |
| Amlodipine | Ibutilide may increase the arrhythmogenic activities of Amlodipine. |
| Digoxin | Ibutilide may increase the arrhythmogenic activities of Digoxin. |
| Hyoscyamine | Ibutilide may increase the arrhythmogenic activities of Hyoscyamine. |
| Lamotrigine | Ibutilide may increase the arrhythmogenic activities of Lamotrigine. |
| Ethosuximide | Ibutilide may increase the arrhythmogenic activities of Ethosuximide. |
| Nicardipine | Ibutilide may increase the arrhythmogenic activities of Nicardipine. |
| Verapamil | Ibutilide may increase the arrhythmogenic activities of Verapamil. |
| Losartan | Ibutilide may increase the arrhythmogenic activities of Losartan. |
| Moricizine | Ibutilide may increase the arrhythmogenic activities of Moricizine. |
| Levomenthol | Ibutilide may increase the arrhythmogenic activities of Levomenthol. |