Peringatan Keamanan

Oral LD50 is 1189-2100 mg/kg in mice, rats and rabbits.

Dapiprazole

DB00298

small molecule approved

Deskripsi

Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.

Struktur Molekul 2D

Berat 325.4512
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Systemic absorption is negligible.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

20 Data
Testosterone undecanoate Testosterone undecanoate may increase the hypertensive activities of Dapiprazole.
Cyclobenzaprine The risk or severity of CNS depression can be increased when Cyclobenzaprine is combined with Dapiprazole.
Metoclopramide The risk or severity of sedation can be increased when Metoclopramide is combined with Dapiprazole.
Lasmiditan The risk or severity of adverse effects can be increased when Lasmiditan is combined with Dapiprazole.
Ziprasidone The risk or severity of adverse effects can be increased when Dapiprazole is combined with Ziprasidone.
Haloperidol The risk or severity of CNS depression can be increased when Haloperidol is combined with Dapiprazole.
Ziconotide The risk or severity of CNS depression can be increased when Dapiprazole is combined with Ziconotide.
Fluoxetine Dapiprazole may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Oliceridine The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Dapiprazole is combined with Oliceridine.
Alfuzosin Dapiprazole may increase the hypotensive activities of Alfuzosin.
Ropeginterferon alfa-2b The risk or severity of neuropsychiatric effects can be increased when Ropeginterferon alfa-2b is combined with Dapiprazole.
Daridorexant The risk or severity of CNS depression can be increased when Dapiprazole is combined with Daridorexant.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Dapiprazole.
Avanafil Dapiprazole may increase the hypotensive activities of Avanafil.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Dapiprazole.
Midazolam The risk or severity of sedation and CNS depression can be increased when Midazolam is combined with Dapiprazole.
Tretinoin The risk or severity of elevated intracranial pressure can be increased when Dapiprazole is combined with Tretinoin.
Ganaxolone The risk or severity of sedation, somnolence, and CNS depression can be increased when Dapiprazole is combined with Ganaxolone.
Zuranolone The risk or severity of CNS depression can be increased when Zuranolone is combined with Dapiprazole.
Iloperidone The risk or severity of hypotension can be increased when Dapiprazole is combined with Iloperidone.

Target Protein

D(2) dopamine receptor DRD2
Alpha-1A adrenergic receptor ADRA1A
Alpha-1D adrenergic receptor ADRA1D
Alpha-1B adrenergic receptor ADRA1B

Referensi & Sumber

Contoh Produk & Brand

Produk: 1 • International brands: 1
Produk
  • Dapiprazole
    Kit; Powder, for solution • 25 mg/5mL • Ophthalmic • US • Generic • Approved
International Brands
  • Rev-Eyes

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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