Peringatan Keamanan

Results from acute toxicity studies do not indicate that any risk of acute intoxication is to be expected following a single dermal application of an overdose (application over a large area under conditions favorable to absorption) or inadvertent oral ingestion.

Amcinonide

DB00288

small molecule approved

Deskripsi

Amcinonide is a corticosteroid.

Struktur Molekul 2D

Berat 502.5717
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption.

Metabolisme

Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys.

Rute Eliminasi

Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.

Interaksi Obat

160 Data
Trastuzumab The risk or severity of neutropenia can be increased when Trastuzumab is combined with Amcinonide.
Tacrolimus Tacrolimus may increase the immunosuppressive activities of Amcinonide.
Phenylephrine The risk or severity of hypertension can be increased when Amcinonide is combined with Phenylephrine.
Aminoglutethimide The therapeutic efficacy of Amcinonide can be decreased when used in combination with Aminoglutethimide.
Insulin human The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin human.
Insulin lispro The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin lispro.
Insulin glargine The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin glargine.
Insulin pork The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin pork.
Troglitazone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Troglitazone.
Glimepiride The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Glimepiride.
Sulfisoxazole The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Sulfisoxazole.
Disopyramide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Disopyramide.
Acarbose The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Acarbose.
Metformin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Metformin.
Sulfadiazine The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Sulfadiazine.
Rosiglitazone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Rosiglitazone.
Acetohexamide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Acetohexamide.
Quinine The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Quinine.
Miglitol The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Miglitol.
Chlorpropamide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Chlorpropamide.
Nateglinide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Nateglinide.
Pentamidine The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Pentamidine.
Mifepristone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Mifepristone.
Tolazamide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Tolazamide.
Repaglinide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Repaglinide.
Phenformin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Phenformin.
Sulfamethoxazole The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Sulfamethoxazole.
Glyburide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Glyburide.
Glipizide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Glipizide.
Gliclazide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Gliclazide.
Tolbutamide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Tolbutamide.
Pioglitazone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Pioglitazone.
Bromocriptine The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Bromocriptine.
Gliquidone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Gliquidone.
Mitiglinide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Mitiglinide.
Sitagliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Sitagliptin.
Sunitinib The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Sunitinib.
Exenatide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Exenatide.
Mecasermin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Mecasermin.
Pramlintide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Pramlintide.
Glisoxepide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Glisoxepide.
Insulin aspart The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin aspart.
Insulin detemir The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin detemir.
Insulin glulisine The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin glulisine.
Glymidine The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Glymidine.
AICA ribonucleotide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with AICA ribonucleotide.
Buformin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Buformin.
Vildagliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Vildagliptin.
Voglibose The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Voglibose.
NN344 The risk or severity of hyperglycemia can be increased when Amcinonide is combined with NN344.
AMG-222 The risk or severity of hyperglycemia can be increased when Amcinonide is combined with AMG-222.
Bisegliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Bisegliptin.
Alogliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Alogliptin.
Dapagliflozin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Dapagliflozin.
Saxagliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Saxagliptin.
Liraglutide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Liraglutide.
Gosogliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Gosogliptin.
Linagliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Linagliptin.
Canagliflozin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Canagliflozin.
Glibornuride The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Glibornuride.
Benfluorex The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Benfluorex.
Empagliflozin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Empagliflozin.
Albiglutide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Albiglutide.
Dulaglutide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Dulaglutide.
Lobeglitazone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Lobeglitazone.
Netoglitazone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Netoglitazone.
Rivoglitazone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Rivoglitazone.
Ciglitazone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Ciglitazone.
Lixisenatide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Lixisenatide.
Insulin beef The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin beef.
Insulin degludec The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin degludec.
Insulin peglispro The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin peglispro.
Insulin tregopil The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Insulin tregopil.
Ipragliflozin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Ipragliflozin.
Dutogliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Dutogliptin.
Allicin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Allicin.
Tofogliflozin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Tofogliflozin.
Ertugliflozin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Ertugliflozin.
2,4-thiazolidinedione The risk or severity of hyperglycemia can be increased when Amcinonide is combined with 2,4-thiazolidinedione.
Teneligliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Teneligliptin.
Omarigliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Omarigliptin.
Carmegliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Carmegliptin.
Gemigliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Gemigliptin.
Anagliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Anagliptin.
Evogliptin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Evogliptin.
Sotagliflozin The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Sotagliflozin.
Balaglitazone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Balaglitazone.
Remogliflozin etabonate The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Remogliflozin etabonate.
Carbutamide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Carbutamide.
Guar gum The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Guar gum.
Metahexamide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Metahexamide.
Semaglutide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Semaglutide.
Taspoglutide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Taspoglutide.
Englitazone The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Englitazone.
Tirzepatide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Tirzepatide.
Gastric inhibitory polypeptide The risk or severity of hyperglycemia can be increased when Amcinonide is combined with Gastric inhibitory polypeptide.
Isoniazid The serum concentration of Isoniazid can be decreased when it is combined with Amcinonide.
Cyclosporine The risk or severity of adverse effects can be increased when Amcinonide is combined with Cyclosporine.
Digoxin The risk or severity of adverse effects can be increased when Amcinonide is combined with Digoxin.
Acetyldigitoxin The risk or severity of adverse effects can be increased when Amcinonide is combined with Acetyldigitoxin.

Target Protein

Steroid hormone receptor ERR1 ESRRA
Steroid hormone receptor ERR2 ESRRB
Estrogen-related receptor gamma ESRRG
Glucocorticoid receptor NR3C1
Annexin A1 ANXA1

Referensi & Sumber

Synthesis reference: Schultz, W., Sieger, G.M. and Krieger, C.: British Patent 1,442,925; July 14,1976; assigned to American Cyanamid Company.

Contoh Produk & Brand

Produk: 20 • International brands: 3
Produk
  • Amcinonide
    Ointment • 1 mg/1g • Topical • US • Generic • Approved
  • Amcinonide
    Lotion • 1 mg/1g • Topical • US • Generic • Approved
  • Amcinonide
    Cream • 1 mg/1g • Topical • US • Generic • Approved
  • Amcinonide
    Cream • 1 mg/1g • Topical • US • Generic • Approved
  • Amcinonide
    Ointment • 1 mg/1g • Topical • US • Generic • Approved
  • Amcinonide
    Ointment • 1 mg/1g • Topical • US • Generic • Approved
  • Amcinonide
    Cream • 1 mg/1g • Topical • US • Generic • Approved
  • Amcinonide
    Cream • 1 mg/1g • Topical • US • Generic • Approved
Menampilkan 8 dari 20 produk.
International Brands
  • Mycoderm
  • Penticort
  • Visderm

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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