Oral LD50 in rats is 3,204 mg/kg. With other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.
A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Probenecid | The serum concentration of Cefmetazole can be increased when it is combined with Probenecid. |
| Foscarnet | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Foscarnet. |
| Mannitol | The risk or severity of nephrotoxicity can be increased when Mannitol is combined with Cefmetazole. |
| Tenofovir disoproxil | Cefmetazole may increase the nephrotoxic activities of Tenofovir disoproxil. |
| Tenofovir alafenamide | Cefmetazole may increase the nephrotoxic activities of Tenofovir alafenamide. |
| Tenofovir | Cefmetazole may increase the nephrotoxic activities of Tenofovir. |
| Cyclosporine | The risk or severity of nephrotoxicity can be increased when Cyclosporine is combined with Cefmetazole. |
| Icosapent | The risk or severity of nephrotoxicity can be increased when Icosapent is combined with Cefmetazole. |
| Cefotiam | The risk or severity of nephrotoxicity can be increased when Cefotiam is combined with Cefmetazole. |
| Mesalazine | The risk or severity of nephrotoxicity can be increased when Mesalazine is combined with Cefmetazole. |
| Cefmenoxime | The risk or severity of nephrotoxicity can be increased when Cefmenoxime is combined with Cefmetazole. |
| Indomethacin | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Indomethacin. |
| Triamterene | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Triamterene. |
| Cefpiramide | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefpiramide. |
| Loracarbef | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Loracarbef. |
| Cefalotin | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefalotin. |
| Nabumetone | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Nabumetone. |
| Ketorolac | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Ketorolac. |
| Tenoxicam | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Tenoxicam. |
| Celecoxib | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Celecoxib. |
| Cefotaxime | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefotaxime. |
| Tolmetin | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Tolmetin. |
| Rofecoxib | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Rofecoxib. |
| Fenoprofen | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Fenoprofen. |
| Valdecoxib | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Valdecoxib. |
| Diclofenac | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Diclofenac. |
| Sulindac | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Sulindac. |
| Bacitracin | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Bacitracin. |
| Amphotericin B | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Amphotericin B. |
| Cephaloglycin | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cephaloglycin. |
| Adefovir dipivoxil | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Adefovir dipivoxil. |
| Pentamidine | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Pentamidine. |
| Mefenamic acid | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Mefenamic acid. |
| Naproxen | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Naproxen. |
| Sulfasalazine | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Sulfasalazine. |
| Phenylbutazone | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Phenylbutazone. |
| Meloxicam | The risk or severity of methemoglobinemia can be increased when Cefmetazole is combined with Meloxicam. |
| Carprofen | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Carprofen. |
| Tacrolimus | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Tacrolimus. |
| Etacrynic acid | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Etacrynic acid. |
| Ceforanide | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Ceforanide. |
| Salicylic acid | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Salicylic acid. |
| Acetylsalicylic acid | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Acetylsalicylic acid. |
| Hydrochlorothiazide | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Hydrochlorothiazide. |
| Balsalazide | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Balsalazide. |
| Cefditoren | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefditoren. |
| Atazanavir | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Atazanavir. |
| Colistimethate | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Colistimethate. |
| Cefuroxime | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefuroxime. |
| Cefapirin | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefapirin. |
| Cefprozil | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefprozil. |
| Olsalazine | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Olsalazine. |
| Lumiracoxib | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Lumiracoxib. |
| Cefamandole | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefamandole. |
| Cefazolin | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefazolin. |
| Cefonicid | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefonicid. |
| Cefoperazone | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefoperazone. |
| Cefoxitin | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefoxitin. |
| Ceftizoxime | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Ceftizoxime. |
| Magnesium salicylate | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Magnesium salicylate. |
| Salsalate | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Salsalate. |
| Choline magnesium trisalicylate | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Choline magnesium trisalicylate. |
| Cefepime | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefepime. |
| Cefacetrile | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefacetrile. |
| Cefpodoxime | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefpodoxime. |
| Antrafenine | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Antrafenine. |
| Aminophenazone | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Aminophenazone. |
| Antipyrine | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Antipyrine. |
| Tiaprofenic acid | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Tiaprofenic acid. |
| Lopinavir | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Lopinavir. |
| Etoricoxib | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Etoricoxib. |
| Hydrolyzed Cephalothin | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Hydrolyzed Cephalothin. |
| Cephalothin Group | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cephalothin Group. |
| Oxyphenbutazone | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Oxyphenbutazone. |
| Latamoxef | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Latamoxef. |
| Nimesulide | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Nimesulide. |
| Benoxaprofen | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Benoxaprofen. |
| Metamizole | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Metamizole. |
| Zomepirac | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Zomepirac. |
| Ceftobiprole | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Ceftobiprole. |
| Cimicoxib | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cimicoxib. |
| Ceftaroline fosamil | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Ceftaroline fosamil. |
| Lornoxicam | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Lornoxicam. |
| Zaltoprofen | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Zaltoprofen. |
| Azapropazone | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Azapropazone. |
| Parecoxib | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Parecoxib. |
| Salicylamide | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Salicylamide. |
| Kebuzone | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Kebuzone. |
| Isoxicam | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Isoxicam. |
| Indoprofen | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Indoprofen. |
| Ibuproxam | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Ibuproxam. |
| Floctafenine | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Floctafenine. |
| Fenbufen | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Fenbufen. |
| Etofenamate | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Etofenamate. |
| Epirizole | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Epirizole. |
| Cefaloridine | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefaloridine. |
| Cefminox | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefminox. |
| Dexibuprofen | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Dexibuprofen. |
| Droxicam | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Droxicam. |
| Tolfenamic acid | The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Tolfenamic acid. |