LD50=6800 mg/kg (Orally in mice)
A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Ivabradine | Ivabradine may increase the QTc-prolonging activities of Sulfisoxazole. |
| Pegvisomant | The risk or severity of hypoglycemia can be increased when Pegvisomant is combined with Sulfisoxazole. |
| Nicotine | The risk or severity of adverse effects can be increased when Sulfisoxazole is combined with Nicotine. |
| Mecamylamine | The risk or severity of adverse effects can be increased when Sulfisoxazole is combined with Mecamylamine. |
| Pentolinium | The risk or severity of adverse effects can be increased when Sulfisoxazole is combined with Pentolinium. |
| Trimethaphan | The risk or severity of adverse effects can be increased when Sulfisoxazole is combined with Trimethaphan. |
| Hexamethonium | The risk or severity of adverse effects can be increased when Sulfisoxazole is combined with Hexamethonium. |
| Cyclopentamine | The risk or severity of adverse effects can be increased when Sulfisoxazole is combined with Cyclopentamine. |
| Methotrexate | The protein binding of Methotrexate can be increased when combined with Sulfisoxazole. |
| Lipoic acid | The risk or severity of hypoglycemia can be increased when Lipoic acid is combined with Sulfisoxazole. |
| Thiopental | The therapeutic efficacy of Thiopental can be increased when used in combination with Sulfisoxazole. |
| Picosulfuric acid | The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Sulfisoxazole. |
| Moxifloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Moxifloxacin. |
| Enoxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Enoxacin. |
| Pefloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Pefloxacin. |
| Ciprofloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Ciprofloxacin. |
| Nalidixic acid | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Nalidixic acid. |
| Rosoxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Rosoxacin. |
| Cinoxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Cinoxacin. |
| Lomefloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Lomefloxacin. |
| Gatifloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Gatifloxacin. |
| Norfloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Norfloxacin. |
| Levofloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Levofloxacin. |
| Gemifloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Gemifloxacin. |
| Ofloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Ofloxacin. |
| Fleroxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Fleroxacin. |
| Technetium Tc-99m ciprofloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Technetium Tc-99m ciprofloxacin. |
| Garenoxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Garenoxacin. |
| Nemonoxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Nemonoxacin. |
| Flumequine | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Flumequine. |
| Enrofloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Enrofloxacin. |
| Orbifloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Orbifloxacin. |
| Sarafloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Sarafloxacin. |
| Difloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Difloxacin. |
| Pazufloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Pazufloxacin. |
| Prulifloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Prulifloxacin. |
| Delafloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Delafloxacin. |
| Sitafloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Sitafloxacin. |
| Oxolinic acid | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Oxolinic acid. |
| Rufloxacin | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Rufloxacin. |
| Pipemidic acid | The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Pipemidic acid. |
| Methyclothiazide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Methyclothiazide. |
| Chlorthalidone | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Chlorthalidone. |
| Bendroflumethiazide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Bendroflumethiazide. |
| Metolazone | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Metolazone. |
| Benzthiazide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Benzthiazide. |
| Hydroflumethiazide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Hydroflumethiazide. |
| Indapamide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Indapamide. |
| Chlorothiazide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Chlorothiazide. |
| Hydrochlorothiazide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Hydrochlorothiazide. |
| Trichlormethiazide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Trichlormethiazide. |
| Polythiazide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Polythiazide. |
| Quinethazone | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Quinethazone. |
| Cyclopenthiazide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Cyclopenthiazide. |
| Epitizide | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Epitizide. |
| Amitriptyline | Amitriptyline may decrease the hypoglycemic activities of Sulfisoxazole. |
| Protriptyline | Protriptyline may decrease the hypoglycemic activities of Sulfisoxazole. |
| Imipramine | Imipramine may decrease the hypoglycemic activities of Sulfisoxazole. |
| Nortriptyline | Nortriptyline may decrease the hypoglycemic activities of Sulfisoxazole. |
| Amoxapine | Amoxapine may decrease the hypoglycemic activities of Sulfisoxazole. |
| Desipramine | Desipramine may decrease the hypoglycemic activities of Sulfisoxazole. |
| Clomipramine | Clomipramine may decrease the hypoglycemic activities of Sulfisoxazole. |
| Amineptine | Amineptine may decrease the hypoglycemic activities of Sulfisoxazole. |
| Dimetacrine | Dimetacrine may decrease the hypoglycemic activities of Sulfisoxazole. |
| Butriptyline | Butriptyline may decrease the hypoglycemic activities of Sulfisoxazole. |
| Dosulepin | Dosulepin may decrease the hypoglycemic activities of Sulfisoxazole. |
| Tianeptine | Tianeptine may decrease the hypoglycemic activities of Sulfisoxazole. |
| Oxaprotiline | Oxaprotiline may decrease the hypoglycemic activities of Sulfisoxazole. |
| Opipramol | Opipramol may decrease the hypoglycemic activities of Sulfisoxazole. |
| Amitriptylinoxide | Amitriptylinoxide may decrease the hypoglycemic activities of Sulfisoxazole. |
| Dibenzepin | Dibenzepin may decrease the hypoglycemic activities of Sulfisoxazole. |
| Quinupramine | Quinupramine may decrease the hypoglycemic activities of Sulfisoxazole. |
| Melitracen | Melitracen may decrease the hypoglycemic activities of Sulfisoxazole. |
| Lofepramine | Lofepramine may decrease the hypoglycemic activities of Sulfisoxazole. |
| Iprindole | Iprindole may decrease the hypoglycemic activities of Sulfisoxazole. |
| Imipramine oxide | Imipramine oxide may decrease the hypoglycemic activities of Sulfisoxazole. |
| Dexketoprofen | The risk or severity of adverse effects can be increased when Dexketoprofen is combined with Sulfisoxazole. |
| Ketoprofen | The risk or severity of adverse effects can be increased when Ketoprofen is combined with Sulfisoxazole. |
| Cyclosporine | The risk or severity of renal failure can be increased when Sulfisoxazole is combined with Cyclosporine. |
| Methenamine | Methenamine can cause a decrease in the absorption of Sulfisoxazole resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Canagliflozin | Canagliflozin may increase the hypoglycemic activities of Sulfisoxazole. |
| Indinavir | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Indinavir. |
| Etonogestrel | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Etonogestrel. |
| Desogestrel | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Desogestrel. |
| Megestrol acetate | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Megestrol acetate. |
| Levonorgestrel | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Levonorgestrel. |
| Progesterone | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Progesterone. |
| Piperazine | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Piperazine. |
| Medroxyprogesterone acetate | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Medroxyprogesterone acetate. |
| Niacin | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Niacin. |
| Epinephrine | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Epinephrine. |
| Norethisterone | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Norethisterone. |
| Ethynodiol diacetate | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Ethynodiol diacetate. |
| Pseudoephedrine | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Pseudoephedrine. |
| Tacrolimus | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Tacrolimus. |
| Sirolimus | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Sirolimus. |
| Etacrynic acid | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Etacrynic acid. |
| Tipranavir | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Tipranavir. |
| Norgestimate | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Norgestimate. |
| Ethinylestradiol | The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Ethinylestradiol. |