Peringatan Keamanan

Side effects include dizziness, drowsiness, headache, constipation, diarrhea, gas pains, loss of appetite, fatigue, and nasal congestion.

Guanadrel

DB00226

small molecule approved

Deskripsi

Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.

Struktur Molekul 2D

Berat 213.2768
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 10 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Rapidly and readily absorbed from the gastrointestinal tract.

Metabolisme

Primarily hepatic

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

635 Data
Alfuzosin Alfuzosin may increase the hypotensive activities of Guanadrel.
Amifostine Guanadrel may increase the hypotensive activities of Amifostine.
Diazoxide Diazoxide may increase the hypotensive activities of Guanadrel.
Methylphenidate Methylphenidate may decrease the antihypertensive activities of Guanadrel.
Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Guanadrel.
Obinutuzumab Guanadrel may increase the hypotensive activities of Obinutuzumab.
Pentoxifylline Pentoxifylline may increase the hypotensive activities of Guanadrel.
Rituximab Guanadrel may increase the hypotensive activities of Rituximab.
Desmopressin Desmopressin may decrease the antihypertensive activities of Guanadrel.
Cyclosporine Cyclosporine may decrease the antihypertensive activities of Guanadrel.
Eletriptan Eletriptan may decrease the antihypertensive activities of Guanadrel.
Methysergide Methysergide may decrease the antihypertensive activities of Guanadrel.
Cabergoline Cabergoline may decrease the antihypertensive activities of Guanadrel.
Atomoxetine Atomoxetine may decrease the antihypertensive activities of Guanadrel.
Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Guanadrel.
Dihydroergotamine Dihydroergotamine may decrease the antihypertensive activities of Guanadrel.
Amitriptyline Amitriptyline may decrease the antihypertensive activities of Guanadrel.
Protriptyline Protriptyline may decrease the antihypertensive activities of Guanadrel.
Methylergometrine Methylergometrine may decrease the antihypertensive activities of Guanadrel.
Mirtazapine Mirtazapine may decrease the antihypertensive activities of Guanadrel.
Promazine Promazine may decrease the antihypertensive activities of Guanadrel.
Droperidol Droperidol may decrease the antihypertensive activities of Guanadrel.
Buspirone Buspirone may decrease the antihypertensive activities of Guanadrel.
Nortriptyline Nortriptyline may decrease the antihypertensive activities of Guanadrel.
Amoxapine Amoxapine may decrease the antihypertensive activities of Guanadrel.
Doxapram Doxapram may decrease the antihypertensive activities of Guanadrel.
Atropine Atropine may decrease the antihypertensive activities of Guanadrel.
Lisuride Lisuride may decrease the antihypertensive activities of Guanadrel.
Trazodone Trazodone may decrease the antihypertensive activities of Guanadrel.
Sumatriptan Sumatriptan may decrease the antihypertensive activities of Guanadrel.
Ergotamine Ergotamine may decrease the antihypertensive activities of Guanadrel.
Nicergoline Nicergoline may decrease the antihypertensive activities of Guanadrel.
Trimipramine Trimipramine may decrease the antihypertensive activities of Guanadrel.
Risperidone Risperidone may decrease the antihypertensive activities of Guanadrel.
Propiomazine Propiomazine may decrease the antihypertensive activities of Guanadrel.
Alfentanil Alfentanil may decrease the antihypertensive activities of Guanadrel.
Fentanyl Fentanyl may decrease the antihypertensive activities of Guanadrel.
Phenmetrazine Phenmetrazine may decrease the antihypertensive activities of Guanadrel.
Trifluoperazine Trifluoperazine may decrease the antihypertensive activities of Guanadrel.
Flupentixol Flupentixol may decrease the antihypertensive activities of Guanadrel.
Quinidine Quinidine may decrease the antihypertensive activities of Guanadrel.
Almotriptan Almotriptan may decrease the antihypertensive activities of Guanadrel.
Naratriptan Naratriptan may decrease the antihypertensive activities of Guanadrel.
Rizatriptan Rizatriptan may decrease the antihypertensive activities of Guanadrel.
Dopamine Dopamine may decrease the antihypertensive activities of Guanadrel.
Frovatriptan Frovatriptan may decrease the antihypertensive activities of Guanadrel.
Methoxyflurane Methoxyflurane may decrease the antihypertensive activities of Guanadrel.
Ergoloid mesylate Ergoloid mesylate may decrease the antihypertensive activities of Guanadrel.
Dutasteride Dutasteride may decrease the antihypertensive activities of Guanadrel.
Doxepin Doxepin may decrease the antihypertensive activities of Guanadrel.
Nefazodone Nefazodone may decrease the antihypertensive activities of Guanadrel.
Desipramine Desipramine may decrease the antihypertensive activities of Guanadrel.
Propafenone Propafenone may decrease the antihypertensive activities of Guanadrel.
Finasteride Finasteride may decrease the antihypertensive activities of Guanadrel.
Paliperidone Paliperidone may decrease the antihypertensive activities of Guanadrel.
Yohimbine Yohimbine may decrease the antihypertensive activities of Guanadrel.
Methotrimeprazine Methotrimeprazine may decrease the antihypertensive activities of Guanadrel.
Solifenacin Solifenacin may decrease the antihypertensive activities of Guanadrel.
Periciazine Periciazine may decrease the antihypertensive activities of Guanadrel.
Acepromazine Acepromazine may decrease the antihypertensive activities of Guanadrel.
Thioproperazine Thioproperazine may decrease the antihypertensive activities of Guanadrel.
Zuclopenthixol Zuclopenthixol may decrease the antihypertensive activities of Guanadrel.
Epicaptopril Epicaptopril may decrease the antihypertensive activities of Guanadrel.
1-benzylimidazole 1-benzylimidazole may decrease the antihypertensive activities of Guanadrel.
Lysergic acid diethylamide Lysergic acid diethylamide may decrease the antihypertensive activities of Guanadrel.
Amineptine Amineptine may decrease the antihypertensive activities of Guanadrel.
Dronedarone Dronedarone may decrease the antihypertensive activities of Guanadrel.
Flibanserin Flibanserin may decrease the antihypertensive activities of Guanadrel.
Iloperidone Iloperidone may decrease the antihypertensive activities of Guanadrel.
Naluzotan Naluzotan may decrease the antihypertensive activities of Guanadrel.
Cariprazine Cariprazine may decrease the antihypertensive activities of Guanadrel.
Mianserin Mianserin may decrease the antihypertensive activities of Guanadrel.
Pizotifen Pizotifen may decrease the antihypertensive activities of Guanadrel.
Asenapine Asenapine may decrease the antihypertensive activities of Guanadrel.
Esmirtazapine Esmirtazapine may decrease the antihypertensive activities of Guanadrel.
Vilazodone Vilazodone may decrease the antihypertensive activities of Guanadrel.
Nitrous oxide Nitrous oxide may decrease the antihypertensive activities of Guanadrel.
Saralasin Saralasin may decrease the antihypertensive activities of Guanadrel.
Cinitapride Cinitapride may decrease the antihypertensive activities of Guanadrel.
Lurasidone Lurasidone may decrease the antihypertensive activities of Guanadrel.
Tyramine Tyramine may decrease the antihypertensive activities of Guanadrel.
Ifenprodil Ifenprodil may decrease the antihypertensive activities of Guanadrel.
Dimetacrine Dimetacrine may decrease the antihypertensive activities of Guanadrel.
Butriptyline Butriptyline may decrease the antihypertensive activities of Guanadrel.
Cannabidiol Cannabidiol may decrease the antihypertensive activities of Guanadrel.
Vortioxetine Vortioxetine may decrease the antihypertensive activities of Guanadrel.
Brexpiprazole Brexpiprazole may decrease the antihypertensive activities of Guanadrel.
Dosulepin Dosulepin may decrease the antihypertensive activities of Guanadrel.
Moxisylyte Moxisylyte may decrease the antihypertensive activities of Guanadrel.
Tianeptine Tianeptine may decrease the antihypertensive activities of Guanadrel.
Oxaprotiline Oxaprotiline may decrease the antihypertensive activities of Guanadrel.
Dihydroergocornine Dihydroergocornine may decrease the antihypertensive activities of Guanadrel.
Atipamezole Atipamezole may decrease the antihypertensive activities of Guanadrel.
Tetrahydrocannabivarin Tetrahydrocannabivarin may decrease the antihypertensive activities of Guanadrel.
Propiverine Propiverine may decrease the antihypertensive activities of Guanadrel.
Piclozotan Piclozotan may decrease the antihypertensive activities of Guanadrel.
Siponimod Siponimod may decrease the antihypertensive activities of Guanadrel.
Idazoxan Idazoxan may decrease the antihypertensive activities of Guanadrel.
Theodrenaline Theodrenaline may decrease the antihypertensive activities of Guanadrel.
Opipramol Opipramol may decrease the antihypertensive activities of Guanadrel.

Target Protein

Sodium-dependent noradrenaline transporter SLC6A2

Referensi & Sumber

Synthesis reference: U.S. Patent 3,547,951.

Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
  • Anarel — Cutter
  • Hylorel — Pennwalt

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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