Remikiren

DB00212

small molecule experimental

Deskripsi

Remikiren is an orally active, high specificity renin inhibitor.

Struktur Molekul 2D

Berat 630.838
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Absorbed following oral administration.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

631 Data
Alfuzosin Alfuzosin may increase the hypotensive activities of Remikiren.
Amifostine Remikiren may increase the hypotensive activities of Amifostine.
Diazoxide Diazoxide may increase the hypotensive activities of Remikiren.
Methylphenidate Methylphenidate may decrease the antihypertensive activities of Remikiren.
Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Remikiren.
Obinutuzumab Remikiren may increase the hypotensive activities of Obinutuzumab.
Pentoxifylline Pentoxifylline may increase the hypotensive activities of Remikiren.
Rituximab Remikiren may increase the hypotensive activities of Rituximab.
Desmopressin Desmopressin may decrease the antihypertensive activities of Remikiren.
Cyclosporine Cyclosporine may decrease the antihypertensive activities of Remikiren.
Phentermine Phentermine may decrease the antihypertensive activities of Remikiren.
Midodrine Midodrine may decrease the antihypertensive activities of Remikiren.
Eletriptan Eletriptan may decrease the antihypertensive activities of Remikiren.
Isoetharine Isoetharine may decrease the antihypertensive activities of Remikiren.
Methysergide Methysergide may decrease the antihypertensive activities of Remikiren.
Cabergoline Cabergoline may decrease the antihypertensive activities of Remikiren.
Atomoxetine Atomoxetine may decrease the antihypertensive activities of Remikiren.
Etomidate Etomidate may decrease the antihypertensive activities of Remikiren.
Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Remikiren.
Dihydroergotamine Dihydroergotamine may decrease the antihypertensive activities of Remikiren.
Amitriptyline Amitriptyline may decrease the antihypertensive activities of Remikiren.
Protriptyline Protriptyline may decrease the antihypertensive activities of Remikiren.
Methylergometrine Methylergometrine may decrease the antihypertensive activities of Remikiren.
Norepinephrine Norepinephrine may decrease the antihypertensive activities of Remikiren.
Mirtazapine Mirtazapine may decrease the antihypertensive activities of Remikiren.
Phenylephrine Phenylephrine may decrease the antihypertensive activities of Remikiren.
Phenylpropanolamine Phenylpropanolamine may decrease the antihypertensive activities of Remikiren.
Promazine Promazine may decrease the antihypertensive activities of Remikiren.
Droperidol Droperidol may decrease the antihypertensive activities of Remikiren.
Buspirone Buspirone may decrease the antihypertensive activities of Remikiren.
Nortriptyline Nortriptyline may decrease the antihypertensive activities of Remikiren.
Amoxapine Amoxapine may decrease the antihypertensive activities of Remikiren.
Doxapram Doxapram may decrease the antihypertensive activities of Remikiren.
Atropine Atropine may decrease the antihypertensive activities of Remikiren.
Lisuride Lisuride may decrease the antihypertensive activities of Remikiren.
Metaraminol Metaraminol may decrease the antihypertensive activities of Remikiren.
Trazodone Trazodone may decrease the antihypertensive activities of Remikiren.
Epinephrine Epinephrine may decrease the antihypertensive activities of Remikiren.
Sumatriptan Sumatriptan may decrease the antihypertensive activities of Remikiren.
Ergotamine Ergotamine may decrease the antihypertensive activities of Remikiren.
Nicergoline Nicergoline may decrease the antihypertensive activities of Remikiren.
Methoxamine Methoxamine may decrease the antihypertensive activities of Remikiren.
Trimipramine Trimipramine may decrease the antihypertensive activities of Remikiren.
Risperidone Risperidone may decrease the antihypertensive activities of Remikiren.
Propiomazine Propiomazine may decrease the antihypertensive activities of Remikiren.
Alfentanil Alfentanil may decrease the antihypertensive activities of Remikiren.
Fentanyl Fentanyl may decrease the antihypertensive activities of Remikiren.
Orciprenaline Orciprenaline may decrease the antihypertensive activities of Remikiren.
Phenmetrazine Phenmetrazine may decrease the antihypertensive activities of Remikiren.
Trifluoperazine Trifluoperazine may decrease the antihypertensive activities of Remikiren.
Dobutamine Dobutamine may decrease the antihypertensive activities of Remikiren.
Pseudoephedrine Pseudoephedrine may decrease the antihypertensive activities of Remikiren.
Benzphetamine Benzphetamine may decrease the antihypertensive activities of Remikiren.
Ritodrine Ritodrine may decrease the antihypertensive activities of Remikiren.
Terbutaline Terbutaline may decrease the antihypertensive activities of Remikiren.
Flupentixol Flupentixol may decrease the antihypertensive activities of Remikiren.
Bitolterol Bitolterol may decrease the antihypertensive activities of Remikiren.
Quinidine Quinidine may decrease the antihypertensive activities of Remikiren.
Almotriptan Almotriptan may decrease the antihypertensive activities of Remikiren.
Diethylpropion Diethylpropion may decrease the antihypertensive activities of Remikiren.
Salmeterol Salmeterol may decrease the antihypertensive activities of Remikiren.
Naratriptan Naratriptan may decrease the antihypertensive activities of Remikiren.
Rizatriptan Rizatriptan may decrease the antihypertensive activities of Remikiren.
Formoterol Formoterol may decrease the antihypertensive activities of Remikiren.
Dopamine Dopamine may decrease the antihypertensive activities of Remikiren.
Frovatriptan Frovatriptan may decrease the antihypertensive activities of Remikiren.
Albuterol Salbutamol may decrease the antihypertensive activities of Remikiren.
Methoxyflurane Methoxyflurane may decrease the antihypertensive activities of Remikiren.
Ergoloid mesylate Ergoloid mesylate may decrease the antihypertensive activities of Remikiren.
Isoprenaline Isoprenaline may decrease the antihypertensive activities of Remikiren.
Arbutamine Arbutamine may decrease the antihypertensive activities of Remikiren.
Dutasteride Dutasteride may decrease the antihypertensive activities of Remikiren.
Doxepin Doxepin may decrease the antihypertensive activities of Remikiren.
Nefazodone Nefazodone may decrease the antihypertensive activities of Remikiren.
Desipramine Desipramine may decrease the antihypertensive activities of Remikiren.
Propafenone Propafenone may decrease the antihypertensive activities of Remikiren.
Pergolide Pergolide may decrease the antihypertensive activities of Remikiren.
Finasteride Finasteride may decrease the antihypertensive activities of Remikiren.
Ergometrine Ergometrine may decrease the antihypertensive activities of Remikiren.
Lisdexamfetamine Lisdexamfetamine may decrease the antihypertensive activities of Remikiren.
Paliperidone Paliperidone may decrease the antihypertensive activities of Remikiren.
Arformoterol Arformoterol may decrease the antihypertensive activities of Remikiren.
Fenoterol Fenoterol may decrease the antihypertensive activities of Remikiren.
Pirbuterol Pirbuterol may decrease the antihypertensive activities of Remikiren.
Ephedra sinica root Ephedra sinica root may decrease the antihypertensive activities of Remikiren.
Ephedrine Ephedrine may decrease the antihypertensive activities of Remikiren.
Mephentermine Mephentermine may decrease the antihypertensive activities of Remikiren.
Procaterol Procaterol may decrease the antihypertensive activities of Remikiren.
Yohimbine Yohimbine may decrease the antihypertensive activities of Remikiren.
Methotrimeprazine Methotrimeprazine may decrease the antihypertensive activities of Remikiren.
Clenbuterol Clenbuterol may decrease the antihypertensive activities of Remikiren.
Bambuterol Bambuterol may decrease the antihypertensive activities of Remikiren.
MMDA MMDA may decrease the antihypertensive activities of Remikiren.
Midomafetamine Midomafetamine may decrease the antihypertensive activities of Remikiren.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Remikiren.
4-Methoxyamphetamine 4-Methoxyamphetamine may decrease the antihypertensive activities of Remikiren.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Remikiren.
Tenamfetamine Tenamfetamine may decrease the antihypertensive activities of Remikiren.
Chlorphentermine Chlorphentermine may decrease the antihypertensive activities of Remikiren.
Dextroamphetamine Dextroamphetamine may decrease the antihypertensive activities of Remikiren.

Target Protein

Renin REN

Referensi & Sumber

Artikel (PubMed)
  • PMID: 8498974
    Clozel JP, Fischli W: Discovery of remikiren as the first orally active renin inhibitor. Arzneimittelforschung. 1993 Feb;43(2A):260-2.
  • PMID: 8730917
    Richter WF, Whitby BR, Chou RC: Distribution of remikiren, a potent orally active inhibitor of human renin, in laboratory animals. Xenobiotica. 1996 Mar;26(3):243-54.

Contoh Produk & Brand

Produk: 0 • International brands: 0
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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