Oral LD50s are 350 to 400 mg betaxolol/kg in mice and 860 to 980 mg/kg in rats. Predicted symptoms of overdose include bradycardia, congestive heart failure, hypotension, bronchospasm, and hypoglycemia.
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Duloxetine | The risk or severity of orthostatic hypotension and syncope can be increased when Betaxolol is combined with Duloxetine. |
| Levodopa | The risk or severity of hypotension and orthostatic hypotension can be increased when Betaxolol is combined with Levodopa. |
| Risperidone | Betaxolol may increase the hypotensive activities of Risperidone. |
| Ceritinib | Betaxolol may increase the bradycardic activities of Ceritinib. |
| Ivabradine | Betaxolol may increase the bradycardic activities of Ivabradine. |
| Ruxolitinib | Ruxolitinib may increase the bradycardic activities of Betaxolol. |
| Deferasirox | The serum concentration of Betaxolol can be increased when it is combined with Deferasirox. |
| Peginterferon alfa-2b | The serum concentration of Betaxolol can be increased when it is combined with Peginterferon alfa-2b. |
| Leflunomide | The serum concentration of Betaxolol can be decreased when it is combined with Leflunomide. |
| Teriflunomide | The serum concentration of Betaxolol can be decreased when it is combined with Teriflunomide. |
| Alfuzosin | Alfuzosin may increase the hypotensive activities of Betaxolol. |
| Amifostine | Betaxolol may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Betaxolol. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Betaxolol. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Betaxolol. |
| Obinutuzumab | Betaxolol may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Betaxolol. |
| Rituximab | Betaxolol may increase the hypotensive activities of Rituximab. |
| Desmopressin | Desmopressin may decrease the antihypertensive activities of Betaxolol. |
| Doxapram | Doxapram may decrease the antihypertensive activities of Betaxolol. |
| Sumatriptan | Sumatriptan may decrease the antihypertensive activities of Betaxolol. |
| Phenmetrazine | Phenmetrazine may decrease the antihypertensive activities of Betaxolol. |
| Naratriptan | Naratriptan may decrease the antihypertensive activities of Betaxolol. |
| Rizatriptan | Rizatriptan may decrease the antihypertensive activities of Betaxolol. |
| Dopamine | Dopamine may decrease the antihypertensive activities of Betaxolol. |
| Dutasteride | Dutasteride may decrease the antihypertensive activities of Betaxolol. |
| Finasteride | Finasteride may decrease the antihypertensive activities of Betaxolol. |
| Yohimbine | Yohimbine may decrease the antihypertensive activities of Betaxolol. |
| Epicaptopril | Epicaptopril may decrease the antihypertensive activities of Betaxolol. |
| 1-benzylimidazole | 1-benzylimidazole may decrease the antihypertensive activities of Betaxolol. |
| Amineptine | Amineptine may decrease the antihypertensive activities of Betaxolol. |
| Flibanserin | Flibanserin may decrease the antihypertensive activities of Betaxolol. |
| Naluzotan | Naluzotan may decrease the antihypertensive activities of Betaxolol. |
| Nitrous oxide | Nitrous oxide may decrease the antihypertensive activities of Betaxolol. |
| Cinitapride | Cinitapride may decrease the antihypertensive activities of Betaxolol. |
| Tyramine | Tyramine may decrease the antihypertensive activities of Betaxolol. |
| Ifenprodil | Ifenprodil may decrease the antihypertensive activities of Betaxolol. |
| Dimetacrine | Dimetacrine may decrease the antihypertensive activities of Betaxolol. |
| Moxisylyte | Moxisylyte may decrease the antihypertensive activities of Betaxolol. |
| Tianeptine | Tianeptine may decrease the antihypertensive activities of Betaxolol. |
| Oxaprotiline | Oxaprotiline may decrease the antihypertensive activities of Betaxolol. |
| Atipamezole | Atipamezole may decrease the antihypertensive activities of Betaxolol. |
| Tetrahydrocannabivarin | Tetrahydrocannabivarin may decrease the antihypertensive activities of Betaxolol. |
| Piclozotan | Piclozotan may decrease the antihypertensive activities of Betaxolol. |
| Siponimod | Siponimod may decrease the antihypertensive activities of Betaxolol. |
| Idazoxan | Idazoxan may decrease the antihypertensive activities of Betaxolol. |
| Tramazoline | Tramazoline may decrease the antihypertensive activities of Betaxolol. |
| Amitriptylinoxide | Amitriptylinoxide may decrease the antihypertensive activities of Betaxolol. |
| Dibenzepin | Dibenzepin may decrease the antihypertensive activities of Betaxolol. |
| Quinupramine | Quinupramine may decrease the antihypertensive activities of Betaxolol. |
| Trichloroethylene | Trichloroethylene may decrease the antihypertensive activities of Betaxolol. |
| Fenozolone | Fenozolone may decrease the antihypertensive activities of Betaxolol. |
| Melitracen | Melitracen may decrease the antihypertensive activities of Betaxolol. |
| Lofepramine | Lofepramine may decrease the antihypertensive activities of Betaxolol. |
| Xenon | Xenon may decrease the antihypertensive activities of Betaxolol. |
| Iprindole | Iprindole may decrease the antihypertensive activities of Betaxolol. |
| Buflomedil | Buflomedil may decrease the antihypertensive activities of Betaxolol. |
| Diethyl ether | Diethyl ether may decrease the antihypertensive activities of Betaxolol. |
| Imipramine oxide | Imipramine oxide may decrease the antihypertensive activities of Betaxolol. |
| Mefenorex | Mefenorex may decrease the antihypertensive activities of Betaxolol. |
| 5-methoxy-N,N-dimethyltryptamine | 5-methoxy-N,N-dimethyltryptamine may decrease the antihypertensive activities of Betaxolol. |
| Quinoline Yellow WS | Quinoline Yellow WS may decrease the antihypertensive activities of Betaxolol. |
| Solriamfetol | Solriamfetol may decrease the antihypertensive activities of Betaxolol. |
| Sufentanil | Sufentanil may decrease the antihypertensive activities of Betaxolol. |
| Remifentanil | Remifentanil may decrease the antihypertensive activities of Betaxolol. |
| Halothane | Halothane may decrease the antihypertensive activities of Betaxolol. |
| Opipramol | Opipramol may decrease the antihypertensive activities of Betaxolol. |
| Selpercatinib | Selpercatinib may decrease the antihypertensive activities of Betaxolol. |
| Naxitamab | Naxitamab may decrease the antihypertensive activities of Betaxolol. |
| Cannabidiol | The metabolism of Betaxolol can be decreased when combined with Cannabidiol. |
| Atomoxetine | Atomoxetine may decrease the antihypertensive activities of Betaxolol. |
| Protriptyline | Protriptyline may decrease the antihypertensive activities of Betaxolol. |
| Isoflurane | Isoflurane may decrease the antihypertensive activities of Betaxolol. |
| Propofol | Propofol may decrease the antihypertensive activities of Betaxolol. |
| Desflurane | Desflurane may decrease the antihypertensive activities of Betaxolol. |
| Sevoflurane | Sevoflurane may decrease the antihypertensive activities of Betaxolol. |
| Solifenacin | Solifenacin may decrease the antihypertensive activities of Betaxolol. |
| Lurasidone | Lurasidone may decrease the antihypertensive activities of Betaxolol. |
| Butriptyline | Butriptyline may decrease the antihypertensive activities of Betaxolol. |
| Amiodarone | The therapeutic efficacy of Betaxolol can be increased when used in combination with Amiodarone. |
| Bupivacaine | The serum concentration of Bupivacaine can be increased when it is combined with Betaxolol. |
| Dipyridamole | Dipyridamole may increase the bradycardic activities of Betaxolol. |
| Disopyramide | Disopyramide may increase the bradycardic activities of Betaxolol. |
| Dronedarone | Dronedarone may increase the bradycardic activities of Betaxolol. |
| Fingolimod | Betaxolol may increase the bradycardic activities of Fingolimod. |
| Floctafenine | The risk or severity of adverse effects can be increased when Betaxolol is combined with Floctafenine. |
| Mepivacaine | The serum concentration of Mepivacaine can be increased when it is combined with Betaxolol. |
| Methacholine | Betaxolol may increase the bronchoconstrictory activities of Methacholine. |
| Midodrine | The therapeutic efficacy of Midodrine can be decreased when used in combination with Betaxolol. |
| Nifedipine | The risk or severity of congestive heart failure and hypotension can be increased when Nifedipine is combined with Betaxolol. |
| Propafenone | The risk or severity of adverse effects can be increased when Propafenone is combined with Betaxolol. |
| Regorafenib | Regorafenib may increase the bradycardic activities of Betaxolol. |
| Reserpine | Reserpine may increase the hypotensive activities of Betaxolol. |
| Deserpidine | Deserpidine may increase the hypotensive activities of Betaxolol. |
| Guanethidine | Guanethidine may increase the hypotensive activities of Betaxolol. |
| Rivastigmine | Betaxolol may increase the bradycardic activities of Rivastigmine. |
| Mirabegron | The serum concentration of Betaxolol can be increased when it is combined with Mirabegron. |
| Abiraterone | The serum concentration of Betaxolol can be increased when it is combined with Abiraterone. |
| Nicorandil | Nicorandil may increase the hypotensive activities of Betaxolol. |
| Molsidomine | Molsidomine may increase the hypotensive activities of Betaxolol. |