Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Mirabegron | The serum concentration of Cevimeline can be increased when it is combined with Mirabegron. |
| Esmolol | The risk or severity of adverse effects can be increased when Esmolol is combined with Cevimeline. |
| Betaxolol | The risk or severity of adverse effects can be increased when Betaxolol is combined with Cevimeline. |
| Atenolol | The risk or severity of adverse effects can be increased when Atenolol is combined with Cevimeline. |
| Alprenolol | The risk or severity of adverse effects can be increased when Alprenolol is combined with Cevimeline. |
| Bevantolol | The risk or severity of adverse effects can be increased when Bevantolol is combined with Cevimeline. |
| Practolol | The risk or severity of adverse effects can be increased when Practolol is combined with Cevimeline. |
| Dexpropranolol | The risk or severity of adverse effects can be increased when Dexpropranolol is combined with Cevimeline. |
| Celiprolol | The risk or severity of adverse effects can be increased when Celiprolol is combined with Cevimeline. |
| Bufuralol | The risk or severity of adverse effects can be increased when Bufuralol is combined with Cevimeline. |
| Bopindolol | The risk or severity of adverse effects can be increased when Bopindolol is combined with Cevimeline. |
| Bupranolol | The risk or severity of adverse effects can be increased when Bupranolol is combined with Cevimeline. |
| Indenolol | The risk or severity of adverse effects can be increased when Indenolol is combined with Cevimeline. |
| Levobetaxolol | The risk or severity of adverse effects can be increased when Levobetaxolol is combined with Cevimeline. |
| Talinolol | The risk or severity of adverse effects can be increased when Talinolol is combined with Cevimeline. |
| Anisodamine | The risk or severity of adverse effects can be increased when Anisodamine is combined with Cevimeline. |
| Bucindolol | The risk or severity of adverse effects can be increased when Bucindolol is combined with Cevimeline. |
| Esatenolol | The risk or severity of adverse effects can be increased when Esatenolol is combined with Cevimeline. |
| Cloranolol | The risk or severity of adverse effects can be increased when Cloranolol is combined with Cevimeline. |
| Mepindolol | The risk or severity of adverse effects can be increased when Mepindolol is combined with Cevimeline. |
| Epanolol | The risk or severity of adverse effects can be increased when Epanolol is combined with Cevimeline. |
| Tertatolol | The risk or severity of adverse effects can be increased when Tertatolol is combined with Cevimeline. |
| Timolol | The risk or severity of adverse effects can be increased when Timolol is combined with Cevimeline. |
| Propranolol | The risk or severity of adverse effects can be increased when Propranolol is combined with Cevimeline. |
| Bisoprolol | The risk or severity of adverse effects can be increased when Bisoprolol is combined with Cevimeline. |
| Pindolol | The risk or severity of adverse effects can be increased when Pindolol is combined with Cevimeline. |
| Nadolol | The risk or severity of adverse effects can be increased when Nadolol is combined with Cevimeline. |
| Penbutolol | The risk or severity of adverse effects can be increased when Penbutolol is combined with Cevimeline. |
| Arotinolol | The risk or severity of adverse effects can be increased when Arotinolol is combined with Cevimeline. |
| Carvedilol | The risk or severity of adverse effects can be increased when Carvedilol is combined with Cevimeline. |
| Nebivolol | The risk or severity of adverse effects can be increased when Nebivolol is combined with Cevimeline. |
| Landiolol | The risk or severity of adverse effects can be increased when Landiolol is combined with Cevimeline. |
| Cimetropium | Cevimeline may decrease the anticholinergic activities of Cimetropium. |
| Tacrine | The risk or severity of adverse effects can be increased when Tacrine is combined with Cevimeline. |
| Sulpiride | The risk or severity of adverse effects can be increased when Sulpiride is combined with Cevimeline. |
| Profenamine | The risk or severity of adverse effects can be increased when Profenamine is combined with Cevimeline. |
| Gallamine triethiodide | The risk or severity of adverse effects can be increased when Gallamine triethiodide is combined with Cevimeline. |
| Triflupromazine | The risk or severity of adverse effects can be increased when Triflupromazine is combined with Cevimeline. |
| Cinchocaine | The risk or severity of adverse effects can be increased when Cinchocaine is combined with Cevimeline. |
| Nizatidine | The risk or severity of adverse effects can be increased when Nizatidine is combined with Cevimeline. |
| Isoflurophate | The risk or severity of adverse effects can be increased when Isoflurophate is combined with Cevimeline. |
| Diethylcarbamazine | The risk or severity of adverse effects can be increased when Diethylcarbamazine is combined with Cevimeline. |
| Procaine | The risk or severity of adverse effects can be increased when Procaine is combined with Cevimeline. |
| Mechlorethamine | The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Cevimeline. |
| Hexafluronium | The risk or severity of adverse effects can be increased when Hexafluronium is combined with Cevimeline. |
| Demecarium | The risk or severity of adverse effects can be increased when Demecarium is combined with Cevimeline. |
| Physostigmine | The risk or severity of adverse effects can be increased when Physostigmine is combined with Cevimeline. |
| Ambenonium | The risk or severity of adverse effects can be increased when Ambenonium is combined with Cevimeline. |
| Tubocurarine | The risk or severity of adverse effects can be increased when Tubocurarine is combined with Cevimeline. |
| Decamethonium | The risk or severity of adverse effects can be increased when Decamethonium is combined with Cevimeline. |
| Pancuronium | The risk or severity of adverse effects can be increased when Pancuronium is combined with Cevimeline. |
| Pipecuronium | The risk or severity of adverse effects can be increased when Pipecuronium is combined with Cevimeline. |
| Ginkgo biloba | The risk or severity of adverse effects can be increased when Ginkgo biloba is combined with Cevimeline. |
| Neostigmine | The risk or severity of adverse effects can be increased when Neostigmine is combined with Cevimeline. |
| Bambuterol | The risk or severity of adverse effects can be increased when Bambuterol is combined with Cevimeline. |
| 1,10-Phenanthroline | The risk or severity of adverse effects can be increased when 1,10-Phenanthroline is combined with Cevimeline. |
| Huperzine A | The risk or severity of adverse effects can be increased when Huperzine A is combined with Cevimeline. |
| Phenserine | The risk or severity of adverse effects can be increased when Phenserine is combined with Cevimeline. |
| Regramostim | The risk or severity of adverse effects can be increased when Regramostim is combined with Cevimeline. |
| Aprotinin | The risk or severity of adverse effects can be increased when Aprotinin is combined with Cevimeline. |
| Betaine | The risk or severity of adverse effects can be increased when Betaine is combined with Cevimeline. |
| Coumaphos | The risk or severity of adverse effects can be increased when Coumaphos is combined with Cevimeline. |
| Dichlorvos | The risk or severity of adverse effects can be increased when Dichlorvos is combined with Cevimeline. |
| Fenthion | The risk or severity of adverse effects can be increased when Fenthion is combined with Cevimeline. |
| Metrifonate | The risk or severity of adverse effects can be increased when Metrifonate is combined with Cevimeline. |
| Acotiamide | The risk or severity of adverse effects can be increased when Acotiamide is combined with Cevimeline. |
| Methanesulfonyl Fluoride | The risk or severity of adverse effects can be increased when Methanesulfonyl Fluoride is combined with Cevimeline. |
| Paraoxon | The risk or severity of adverse effects can be increased when Paraoxon is combined with Cevimeline. |
| Tyrothricin | The risk or severity of adverse effects can be increased when Tyrothricin is combined with Cevimeline. |
| Ipidacrine | The risk or severity of adverse effects can be increased when Ipidacrine is combined with Cevimeline. |
| Distigmine | The risk or severity of adverse effects can be increased when Distigmine is combined with Cevimeline. |
| Tretamine | The risk or severity of adverse effects can be increased when Tretamine is combined with Cevimeline. |
| Posiphen | The risk or severity of adverse effects can be increased when Posiphen is combined with Cevimeline. |
| Pyridostigmine | The risk or severity of adverse effects can be increased when Pyridostigmine is combined with Cevimeline. |
| Rivastigmine | The risk or severity of adverse effects can be increased when Rivastigmine is combined with Cevimeline. |
| Methylphosphinic Acid | The risk or severity of adverse effects can be increased when Methylphosphinic Acid is combined with Cevimeline. |
| Pegvisomant | The risk or severity of adverse effects can be increased when Pegvisomant is combined with Cevimeline. |
| Mefloquine | The risk or severity of adverse effects can be increased when Mefloquine is combined with Cevimeline. |
| Thiotepa | The risk or severity of adverse effects can be increased when Thiotepa is combined with Cevimeline. |
| Capsaicin | The risk or severity of adverse effects can be increased when Capsaicin is combined with Cevimeline. |
| Celecoxib | The metabolism of Cevimeline can be decreased when combined with Celecoxib. |
| Fluvoxamine | The metabolism of Cevimeline can be decreased when combined with Fluvoxamine. |
| Metoprolol | The metabolism of Cevimeline can be decreased when combined with Metoprolol. |
| Venlafaxine | Cevimeline may decrease the excretion rate of Venlafaxine which could result in a higher serum level. |
| Clobazam | The serum concentration of Cevimeline can be increased when it is combined with Clobazam. |
| Clozapine | The serum concentration of Cevimeline can be increased when it is combined with Clozapine. |
| Duloxetine | The metabolism of Cevimeline can be decreased when combined with Duloxetine. |
| Chlorpromazine | The metabolism of Cevimeline can be decreased when combined with Chlorpromazine. |
| Cimetidine | Cevimeline may decrease the excretion rate of Cimetidine which could result in a higher serum level. |
| Chloroquine | The metabolism of Cevimeline can be decreased when combined with Chloroquine. |
| Nicardipine | The metabolism of Cevimeline can be decreased when combined with Nicardipine. |
| Primaquine | The metabolism of Cevimeline can be decreased when combined with Primaquine. |
| Fusidic acid | The metabolism of Cevimeline can be decreased when combined with Fusidic acid. |
| Cholecalciferol | The metabolism of Cevimeline can be decreased when combined with Cholecalciferol. |
| Tranylcypromine | The metabolism of Cevimeline can be decreased when combined with Tranylcypromine. |
| Perhexiline | The metabolism of Cevimeline can be decreased when combined with Perhexiline. |
| Tegaserod | The metabolism of Cevimeline can be decreased when combined with Tegaserod. |
| Abiraterone | The metabolism of Cevimeline can be decreased when combined with Abiraterone. |
| Panobinostat | The metabolism of Cevimeline can be decreased when combined with Panobinostat. |
| Vilazodone | The metabolism of Cevimeline can be decreased when combined with Vilazodone. |