Flunisolide

DB00180

small molecule approved investigational

Deskripsi

Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.

Struktur Molekul 2D

Berat 434.4977
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 1.8 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Absorbed rapidly

Metabolisme

Primarily hepatic, converted to the S beta-OH metabolite.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1080 Data
Denosumab The risk or severity of adverse effects can be increased when Denosumab is combined with Flunisolide.
Peginterferon alfa-2a The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Flunisolide.
Interferon alfa-n1 The risk or severity of adverse effects can be increased when Interferon alfa-n1 is combined with Flunisolide.
Interferon alfa-n3 The risk or severity of adverse effects can be increased when Interferon alfa-n3 is combined with Flunisolide.
Peginterferon alfa-2b The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Flunisolide.
Interferon gamma-1b The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Flunisolide.
Interferon alfa-2a The risk or severity of adverse effects can be increased when Interferon alfa-2a is combined with Flunisolide.
Aldesleukin The risk or severity of adverse effects can be increased when Aldesleukin is combined with Flunisolide.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Flunisolide.
Pegaspargase The risk or severity of adverse effects can be increased when Pegaspargase is combined with Flunisolide.
Interferon beta-1b The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Flunisolide.
Interferon alfacon-1 The risk or severity of adverse effects can be increased when Interferon alfacon-1 is combined with Flunisolide.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Flunisolide.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Flunisolide.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Flunisolide.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Flunisolide.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Flunisolide.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Flunisolide.
Alefacept The risk or severity of adverse effects can be increased when Alefacept is combined with Flunisolide.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Flunisolide.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Flunisolide.
Interferon alfa-2b The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Flunisolide.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Flunisolide.
Phenylalanine The risk or severity of adverse effects can be increased when Phenylalanine is combined with Flunisolide.
Cladribine Flunisolide may increase the immunosuppressive activities of Cladribine.
Carmustine The risk or severity of adverse effects can be increased when Flunisolide is combined with Carmustine.
Amsacrine The risk or severity of adverse effects can be increased when Flunisolide is combined with Amsacrine.
Bleomycin The risk or severity of adverse effects can be increased when Flunisolide is combined with Bleomycin.
Chlorambucil The risk or severity of adverse effects can be increased when Flunisolide is combined with Chlorambucil.
Raltitrexed The risk or severity of adverse effects can be increased when Flunisolide is combined with Raltitrexed.
Mitomycin The risk or severity of adverse effects can be increased when Flunisolide is combined with Mitomycin.
Bexarotene The risk or severity of adverse effects can be increased when Flunisolide is combined with Bexarotene.
Floxuridine The risk or severity of adverse effects can be increased when Flunisolide is combined with Floxuridine.
Tioguanine The risk or severity of adverse effects can be increased when Flunisolide is combined with Tioguanine.
Dexrazoxane The risk or severity of adverse effects can be increased when Flunisolide is combined with Dexrazoxane.
Streptozocin The risk or severity of adverse effects can be increased when Flunisolide is combined with Streptozocin.
Trifluridine The risk or severity of adverse effects can be increased when Flunisolide is combined with Trifluridine.
Gemcitabine The risk or severity of adverse effects can be increased when Flunisolide is combined with Gemcitabine.
Epirubicin The risk or severity of adverse effects can be increased when Flunisolide is combined with Epirubicin.
Chloramphenicol The risk or severity of adverse effects can be increased when Flunisolide is combined with Chloramphenicol.
Lenalidomide The risk or severity of adverse effects can be increased when Flunisolide is combined with Lenalidomide.
Altretamine The risk or severity of adverse effects can be increased when Flunisolide is combined with Altretamine.
Zidovudine The risk or severity of adverse effects can be increased when Flunisolide is combined with Zidovudine.
Oxaliplatin The risk or severity of adverse effects can be increased when Flunisolide is combined with Oxaliplatin.
Fluorouracil The risk or severity of adverse effects can be increased when Flunisolide is combined with Fluorouracil.
Propylthiouracil The risk or severity of adverse effects can be increased when Flunisolide is combined with Propylthiouracil.
Pentostatin The risk or severity of adverse effects can be increased when Flunisolide is combined with Pentostatin.
Linezolid The risk or severity of adverse effects can be increased when Flunisolide is combined with Linezolid.
Clofarabine The risk or severity of adverse effects can be increased when Flunisolide is combined with Clofarabine.
Pemetrexed The risk or severity of adverse effects can be increased when Flunisolide is combined with Pemetrexed.
Mycophenolate mofetil The risk or severity of adverse effects can be increased when Flunisolide is combined with Mycophenolate mofetil.
Dacarbazine The risk or severity of adverse effects can be increased when Flunisolide is combined with Dacarbazine.
Temozolomide The risk or severity of adverse effects can be increased when Flunisolide is combined with Temozolomide.
Penicillamine The risk or severity of adverse effects can be increased when Flunisolide is combined with Penicillamine.
Azacitidine The risk or severity of adverse effects can be increased when Flunisolide is combined with Azacitidine.
Carboplatin The risk or severity of adverse effects can be increased when Flunisolide is combined with Carboplatin.
Dactinomycin The risk or severity of adverse effects can be increased when Flunisolide is combined with Dactinomycin.
Azathioprine The risk or severity of adverse effects can be increased when Flunisolide is combined with Azathioprine.
Hydroxyurea The risk or severity of adverse effects can be increased when Flunisolide is combined with Hydroxyurea.
Mycophenolic acid The risk or severity of adverse effects can be increased when Flunisolide is combined with Mycophenolic acid.
Topotecan The risk or severity of adverse effects can be increased when Flunisolide is combined with Topotecan.
Mercaptopurine The risk or severity of adverse effects can be increased when Flunisolide is combined with Mercaptopurine.
Thalidomide The risk or severity of adverse effects can be increased when Flunisolide is combined with Thalidomide.
Melphalan The risk or severity of adverse effects can be increased when Flunisolide is combined with Melphalan.
Fludarabine The risk or severity of adverse effects can be increased when Flunisolide is combined with Fludarabine.
Flucytosine The risk or severity of adverse effects can be increased when Flunisolide is combined with Flucytosine.
Capecitabine The risk or severity of adverse effects can be increased when Flunisolide is combined with Capecitabine.
Procarbazine The risk or severity of adverse effects can be increased when Flunisolide is combined with Procarbazine.
Arsenic trioxide The risk or severity of adverse effects can be increased when Flunisolide is combined with Arsenic trioxide.
Idarubicin The risk or severity of adverse effects can be increased when Flunisolide is combined with Idarubicin.
Estramustine The risk or severity of adverse effects can be increased when Flunisolide is combined with Estramustine.
Mitoxantrone The risk or severity of adverse effects can be increased when Flunisolide is combined with Mitoxantrone.
Lomustine The risk or severity of adverse effects can be increased when Flunisolide is combined with Lomustine.
Eculizumab The risk or severity of adverse effects can be increased when Flunisolide is combined with Eculizumab.
Decitabine The risk or severity of adverse effects can be increased when Flunisolide is combined with Decitabine.
Nelarabine The risk or severity of adverse effects can be increased when Flunisolide is combined with Nelarabine.
Stepronin The risk or severity of adverse effects can be increased when Flunisolide is combined with Stepronin.
Hydroxychloroquine The risk or severity of adverse effects can be increased when Flunisolide is combined with Hydroxychloroquine.
Castanospermine The risk or severity of adverse effects can be increased when Flunisolide is combined with Castanospermine.
Vorinostat The risk or severity of adverse effects can be increased when Flunisolide is combined with Vorinostat.
2-Methoxyethanol The risk or severity of adverse effects can be increased when Flunisolide is combined with 2-Methoxyethanol.
Brequinar The risk or severity of adverse effects can be increased when Flunisolide is combined with Brequinar.
Pirfenidone The risk or severity of adverse effects can be increased when Flunisolide is combined with Pirfenidone.
Interferon alfa The risk or severity of adverse effects can be increased when Flunisolide is combined with Interferon alfa.
Glatiramer The risk or severity of adverse effects can be increased when Flunisolide is combined with Glatiramer.
Briakinumab The risk or severity of adverse effects can be increased when Flunisolide is combined with Briakinumab.
Human interferon omega-1 The risk or severity of adverse effects can be increased when Flunisolide is combined with Human interferon omega-1.
Mepolizumab The risk or severity of adverse effects can be increased when Flunisolide is combined with Mepolizumab.
Abetimus The risk or severity of adverse effects can be increased when Flunisolide is combined with Abetimus.
Belatacept The risk or severity of adverse effects can be increased when Flunisolide is combined with Belatacept.
Bendamustine The risk or severity of adverse effects can be increased when Flunisolide is combined with Bendamustine.
Pralatrexate The risk or severity of adverse effects can be increased when Flunisolide is combined with Pralatrexate.
Wortmannin The risk or severity of adverse effects can be increased when Flunisolide is combined with Wortmannin.
Eribulin The risk or severity of adverse effects can be increased when Flunisolide is combined with Eribulin.
Belimumab The risk or severity of adverse effects can be increased when Flunisolide is combined with Belimumab.
Teriflunomide The risk or severity of adverse effects can be increased when Flunisolide is combined with Teriflunomide.
Carfilzomib The risk or severity of adverse effects can be increased when Flunisolide is combined with Carfilzomib.
Dimethyl fumarate The risk or severity of adverse effects can be increased when Flunisolide is combined with Dimethyl fumarate.
Obinutuzumab The risk or severity of adverse effects can be increased when Flunisolide is combined with Obinutuzumab.
Vedolizumab The risk or severity of adverse effects can be increased when Flunisolide is combined with Vedolizumab.

Target Protein

Glucocorticoid receptor NR3C1

Referensi & Sumber

Synthesis reference: Richard E. Jones, Jacquelyn A. Smithers, "Process for preparing flunisolide." U.S. Patent US4273710, issued July, 1965.

Contoh Produk & Brand

Produk: 23 • International brands: 3
Produk
  • Aerobid
    Aerosol, metered • 250 ug/1 • Respiratory (inhalation) • US
  • Aerobid
    Aerosol, metered • 250 ug/1 • Respiratory (inhalation) • US
  • Aerobid
    Aerosol, metered • 250 ug/1 • Respiratory (inhalation) • US • Approved
  • Aerobid-M
    Aerosol, metered • 250 ug/1 • Respiratory (inhalation) • US • Approved
  • Aerospan
    Aerosol, metered • 80 ug/1 • Respiratory (inhalation) • US • Approved
  • Aerospan
    Aerosol, metered • 80 ug/1 • Respiratory (inhalation) • US • Approved
  • Aerospan
    Aerosol, metered • 80 ug/1 • Respiratory (inhalation) • US • Approved
  • Apo-flunisolide Nasal Spray
    Spray, metered • 0.25 mg / mL • Nasal • Canada • Generic • Approved
Menampilkan 8 dari 23 produk.
International Brands
  • Bronalide — Krewel
  • Nasalide — Teva Santé
  • Syntaris — Teva

Sekuens Gen/Protein (FASTA)

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