Proline

DB00172

small molecule nutraceutical

Deskripsi

Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond. Proline is a non-essential amino acid that is synthesized from glutamic acid. It is an essential component of collagen and is important for proper functioning of joints and tendons.

Struktur Molekul 2D

Berat 115.1305

Wujud solid

Peta Jejaring Molekuler

Obat Target Gen Interaksi Enzim Transporter Carrier

Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

1. Pendahuluan & Konsep

Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).

2. Sumber Data (Validasi)

Data Obat: Diekstraksi dari elemen drugbank-id dan name pada skema XML DrugBank.
Target Protein: Diambil dari elemen targets/target yang memuat polipeptida sasaran.
Genetik: Disinkronisasi dari sub-elemen gene-name dan varian snp-effects.
Genetik: Jumlah titik node dibatasi pada maksimal 10 (Slice=10) interaksi untuk menghindari tumpukan data.

3. Algoritma Visualisasi

Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.

4. Legenda Visual

Obat Utama (Pusat Analisis)

Target Protein (Mekanisme)

Gen (Faktor Genetik)

Metode ini mendukung analisis Precision Medicine dan evaluasi risiko Drug-Drug Interaction (DDI).

Profil Farmakokinetik

Waktu Paruh (Half-Life) -

Volume Distribusi -

Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Hepatic

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

0 Data

Tidak ada data.

Target Protein

Peptidyl-prolyl cis-trans isomerase B PPIB

Peptidyl-prolyl cis-trans isomerase A PPIA

Pyrroline-5-carboxylate reductase 1, mitochondrial PYCR1

Bifunctional glutamate/proline--tRNA ligase EPRS1

Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14

Sodium-dependent proline transporter SLC6A7

Pyrroline-5-carboxylate reductase 2 PYCR2

Prolyl 4-hydroxylase subunit alpha-2 P4HA2

Proline dehydrogenase 1, mitochondrial PRODH

Peptidyl-prolyl cis-trans isomerase H PPIH

Pyridoxal phosphate homeostasis protein PLPBP

Prolyl 4-hydroxylase subunit alpha-1 P4HA1

Peptidyl-prolyl cis-trans isomerase F, mitochondrial PPIF

Peptidyl-prolyl cis-trans isomerase C PPIC

Peptidyl-prolyl cis-trans isomerase G PPIG

Prolyl 3-hydroxylase 1 P3H1

Pyrroline-5-carboxylate reductase P5CR2

Probable proline--tRNA ligase, mitochondrial PARS2

Prolyl 3-hydroxylase 2 P3H2

Prolyl 3-hydroxylase 3 P3H3

Pyrroline-5-carboxylate reductase 3 PYCR3

Trans-3-hydroxy-L-proline dehydratase L3HYPDH

Referensi & Sumber

Synthesis reference: Richard I. Leavitt, "L-Proline production from algae." U.S. Patent US4383039, issued October, 1968.

Contoh Produk & Brand

Produk: 232 • International brands: 0

Produk

2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose

Solution • - • Intravenous • Canada • Approved
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix

Solution • - • Intravenous • Canada • Approved
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix

Solution • - • Intravenous • Canada • Approved
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex

Liquid • - • Intravenous • Canada • Approved
2.75% Travas. Amino Acid InJ.W.elecw.25%dex

Liquid • - • Intravenous • Canada • Approved
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix

Solution • - • Intravenous • Canada • Approved
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix

Solution • - • Intravenous • Canada • Approved
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.

Liquid • - • Intravenous • Canada • Approved

Menampilkan 8 dari 232 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.