Bone pain, constipation (especially in children or adolescents), diarrhea, drowsiness, dryness of mouth; headache (continuing), increased thirst, increase in frequency of urination, especially at night, or in amount of urine, irregular heartbeat, itching skin, loss of appetite, metallic taste, muscle pain, nausea or vomiting (especially in children or adolescents), unusual tiredness or weakness.
The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Aluminum hydroxide | The serum concentration of Aluminum hydroxide can be increased when it is combined with Calcifediol. |
| Danazol | Danazol may increase the hypercalcemic activities of Calcifediol. |
| Sucralfate | The serum concentration of Sucralfate can be increased when it is combined with Calcifediol. |
| Orlistat | Orlistat can cause a decrease in the absorption of Calcifediol resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Magnesium sulfate | The serum concentration of Magnesium sulfate can be increased when it is combined with Calcifediol. |
| Magnesium oxide | The serum concentration of Magnesium oxide can be increased when it is combined with Calcifediol. |
| Magnesium salicylate | The serum concentration of Magnesium salicylate can be increased when it is combined with Calcifediol. |
| Magaldrate | The serum concentration of Magaldrate can be increased when it is combined with Calcifediol. |
| Magnesium hydroxide | The serum concentration of Magnesium hydroxide can be increased when it is combined with Calcifediol. |
| Magnesium trisilicate | The serum concentration of Magnesium trisilicate can be increased when it is combined with Calcifediol. |
| Magnesium chloride | The serum concentration of Magnesium chloride can be increased when it is combined with Calcifediol. |
| Magnesium carbonate | The serum concentration of Magnesium carbonate can be increased when it is combined with Calcifediol. |
| Talc | The serum concentration of Talc can be increased when it is combined with Calcifediol. |
| Magnesium citrate | The serum concentration of Magnesium citrate can be increased when it is combined with Calcifediol. |
| Magnesium silicate | The serum concentration of Magnesium silicate can be increased when it is combined with Calcifediol. |
| Hydrotalcite | The serum concentration of Hydrotalcite can be increased when it is combined with Calcifediol. |
| Magnesium aspartate | The serum concentration of Magnesium aspartate can be increased when it is combined with Calcifediol. |
| Magnesium peroxide | The serum concentration of Magnesium peroxide can be increased when it is combined with Calcifediol. |
| Magnesium gluconate | The serum concentration of Magnesium gluconate can be increased when it is combined with Calcifediol. |
| Magnesium orotate | The serum concentration of Magnesium orotate can be increased when it is combined with Calcifediol. |
| Magnesium | The serum concentration of Magnesium can be increased when it is combined with Calcifediol. |
| Magnesium levulinate | The serum concentration of Magnesium levulinate can be increased when it is combined with Calcifediol. |
| Magnesium lactate | The serum concentration of Magnesium lactate can be increased when it is combined with Calcifediol. |
| Digoxin | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Digoxin. |
| Acetyldigitoxin | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Acetyldigitoxin. |
| Deslanoside | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Deslanoside. |
| Ouabain | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Ouabain. |
| Digitoxin | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Digitoxin. |
| Oleandrin | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Oleandrin. |
| Cymarin | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Cymarin. |
| Proscillaridin | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Proscillaridin. |
| Metildigoxin | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Metildigoxin. |
| Lanatoside C | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Lanatoside C. |
| Gitoformate | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Gitoformate. |
| Acetyldigoxin | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Acetyldigoxin. |
| Peruvoside | The risk or severity of ventricular arrhythmias and Cardiac Arrhythmia can be increased when Calcifediol is combined with Peruvoside. |
| Mineral oil | Mineral oil can cause a decrease in the absorption of Calcifediol resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Methyclothiazide | The risk or severity of hypercalcemia can be increased when Methyclothiazide is combined with Calcifediol. |
| Bendroflumethiazide | The risk or severity of hypercalcemia can be increased when Bendroflumethiazide is combined with Calcifediol. |
| Benzthiazide | The risk or severity of hypercalcemia can be increased when Benzthiazide is combined with Calcifediol. |
| Cyclothiazide | The risk or severity of hypercalcemia can be increased when Cyclothiazide is combined with Calcifediol. |
| Hydroflumethiazide | The risk or severity of hypercalcemia can be increased when Hydroflumethiazide is combined with Calcifediol. |
| Chlorothiazide | The risk or severity of hypercalcemia can be increased when Chlorothiazide is combined with Calcifediol. |
| Hydrochlorothiazide | The risk or severity of hypercalcemia can be increased when Hydrochlorothiazide is combined with Calcifediol. |
| Trichlormethiazide | The risk or severity of hypercalcemia can be increased when Trichlormethiazide is combined with Calcifediol. |
| Polythiazide | The risk or severity of hypercalcemia can be increased when Polythiazide is combined with Calcifediol. |
| Mebutizide | The risk or severity of hypercalcemia can be increased when Mebutizide is combined with Calcifediol. |
| Cyclopenthiazide | The risk or severity of hypercalcemia can be increased when Cyclopenthiazide is combined with Calcifediol. |
| Buthiazide | The risk or severity of hypercalcemia can be increased when Buthiazide is combined with Calcifediol. |
| Calcitriol | The risk or severity of adverse effects can be increased when Calcitriol is combined with Calcifediol. |
| Ergocalciferol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Ergocalciferol. |
| Cholecalciferol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Cholecalciferol. |
| Paricalcitol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Paricalcitol. |
| Dihydrotachysterol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Dihydrotachysterol. |
| Alfacalcidol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Alfacalcidol. |
| Seocalcitol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Seocalcitol. |
| Inecalcitol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Inecalcitol. |
| Becocalcidiol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Becocalcidiol. |
| Eldecalcitol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Eldecalcitol. |
| 1alpha,24S-Dihydroxyvitamin D2 | The risk or severity of adverse effects can be increased when Calcifediol is combined with 1alpha,24S-Dihydroxyvitamin D2. |
| Elocalcitol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Elocalcitol. |
| Maxacalcitol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Maxacalcitol. |
| Doxercalciferol | The risk or severity of adverse effects can be increased when Calcifediol is combined with Doxercalciferol. |
| Vitamin D | The risk or severity of adverse effects can be increased when Calcifediol is combined with Vitamin D. |
| 1alpha-Hydroxyvitamin D5 | The risk or severity of adverse effects can be increased when Calcifediol is combined with 1alpha-Hydroxyvitamin D5. |
| Previtamin D(3) | The risk or severity of adverse effects can be increased when Calcifediol is combined with Previtamin D(3). |
| Calcium acetate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium acetate. |
| Calcium glucoheptonate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium glucoheptonate. |
| Calcium chloride | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium chloride. |
| Calcium | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium. |
| Calcium carbonate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium carbonate. |
| Calcium citrate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium citrate. |
| Calcium gluconate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium gluconate. |
| Calcium Phosphate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium Phosphate. |
| Calcium glubionate anhydrous | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium glubionate anhydrous. |
| Calcium lactate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium lactate. |
| Calcium lactate gluconate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium lactate gluconate. |
| Calcium pangamate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium pangamate. |
| Calcium levulinate | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium levulinate. |
| Calcium cation | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium cation. |
| Calcium polycarbophil | The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium polycarbophil. |
| Colestipol | The serum concentration of Calcifediol can be decreased when it is combined with Colestipol. |
| Sevelamer | The serum concentration of Calcifediol can be decreased when it is combined with Sevelamer. |
| Colesevelam | The serum concentration of Calcifediol can be decreased when it is combined with Colesevelam. |
| Cholestyramine | The serum concentration of Calcifediol can be decreased when it is combined with Cholestyramine. |
| Flunisolide | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Flunisolide. |
| Beclomethasone dipropionate | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Beclomethasone dipropionate. |
| Betamethasone | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Betamethasone. |
| Fluticasone propionate | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Fluticasone propionate. |
| Fluocinolone acetonide | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Fluocinolone acetonide. |
| Triamcinolone | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Triamcinolone. |
| Prednisone | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Prednisone. |
| Fludrocortisone | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Fludrocortisone. |
| Hydrocortisone | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Hydrocortisone. |
| Prednisolone | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Prednisolone. |
| Methylprednisolone | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Methylprednisolone. |
| Trilostane | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Trilostane. |
| Budesonide | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Budesonide. |
| Dexamethasone | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Dexamethasone. |
| Corticotropin | The therapeutic efficacy of Calcifediol can be decreased when used in combination with Corticotropin. |