Peringatan Keamanan

ORL-RAT LD50 7930 mg/kg, SCU-RAT LD50 5200 mg/kg, IVN-RAT LD50 2600 mg/kg, ORL-MUS LD50 4920 mg/kg; Doses of 1 gram daily are very well tolerated. Mild gastrointestinal symptoms are infrequently noted. In one study doses of 90 grams daily were also well tole.

Glycine

DB00145

small molecule approved nutraceutical vet_approved

Deskripsi

A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

Struktur Molekul 2D

Berat 75.0666
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Absorbed from the small intestine via an active transport mechanism.

Metabolisme

Hepatic

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

8 Data
Digoxin The risk or severity of adverse effects can be increased when Glycine is combined with Digoxin.
Acetyldigitoxin The risk or severity of adverse effects can be increased when Glycine is combined with Acetyldigitoxin.
Deslanoside The risk or severity of adverse effects can be increased when Glycine is combined with Deslanoside.
Digitoxin The risk or severity of adverse effects can be increased when Glycine is combined with Digitoxin.
Metildigoxin The risk or severity of adverse effects can be increased when Glycine is combined with Metildigoxin.
Lanatoside C The risk or severity of adverse effects can be increased when Glycine is combined with Lanatoside C.
Gitoformate The risk or severity of adverse effects can be increased when Glycine is combined with Gitoformate.
Acetyldigoxin The risk or severity of adverse effects can be increased when Glycine is combined with Acetyldigoxin.

Target Protein

Glutamate receptor ionotropic, NMDA 2A GRIN2A
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT
5-aminolevulinate synthase, non-specific, mitochondrial ALAS1
5-aminolevulinate synthase, erythroid-specific, mitochondrial ALAS2
Glycine--tRNA ligase GARS1
Bile acid-CoA:amino acid N-acyltransferase BAAT
N-arachidonyl glycine receptor GPR18
Glutathione synthetase GSS
Glutamate receptor ionotropic, NMDA 2C GRIN2C
Serine hydroxymethyltransferase
Glycine N-acyltransferase GLYAT
Serine hydroxymethyltransferase, mitochondrial SHMT2
Glycine N-acyltransferase-like protein 2 GLYATL2
Glycine N-acyltransferase-like protein 1 GLYATL1
Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2
Peroxisomal sarcosine oxidase PIPOX
Glutamate receptor ionotropic, NMDA 3B GRIN3B
Glycine receptor subunit alpha-1 GLRA1
Alanine--glyoxylate aminotransferase AGXT
Glycine receptor subunit beta GLRB
Serine hydroxymethyltransferase, cytosolic SHMT1
Glycine receptor subunit alpha-3 GLRA3
Glycine receptor subunit alpha-2 GLRA2
Glycine N-methyltransferase GNMT
Glycine amidinotransferase, mitochondrial GATM

Referensi & Sumber

Synthesis reference: Koichi Niimura, Takako Kawabe, Takao Ando, Kenichi Saito, "Phenylalanine-glycine compounds having anti-tumor activity, process for preparation thereof, and pharmaceutical composition containing said compounds." U.S. Patent US5411964, issued August, 1908.

Contoh Produk & Brand

Produk: 248 • International brands: 1
Produk
  • 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
    Solution • - • Intravenous • Canada • Approved
  • 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
    Solution • - • Intravenous • Canada • Approved
  • 2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
    Solution • - • Intravenous • Canada • Approved
  • 2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
    Liquid • - • Intravenous • Canada • Approved
  • 2.75% Travas. Amino Acid InJ.W.elecw.25%dex
    Liquid • - • Intravenous • Canada • Approved
  • 2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
    Solution • - • Intravenous • Canada • Approved
  • 2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
    Solution • - • Intravenous • Canada • Approved
  • 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
    Liquid • - • Intravenous • Canada • Approved
Menampilkan 8 dari 248 produk.
International Brands
  • Gyn-Hydralin

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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