Riboflavin

DB00140

small molecule approved investigational nutraceutical vet_approved

Deskripsi

Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.

Struktur Molekul 2D

Berat 376.3639
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 66-84 minutes
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Vitamin B2 is readily absorbed from the upper gastrointestinal tract.

Metabolisme

Hepatic.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

41 Data
Porfimer sodium Riboflavin may increase the photosensitizing activities of Porfimer sodium.
Verteporfin Riboflavin may increase the photosensitizing activities of Verteporfin.
Citrulline The excretion of Citrulline can be decreased when combined with Riboflavin.
Cefotiam The excretion of Cefotiam can be decreased when combined with Riboflavin.
Tenofovir disoproxil The excretion of Tenofovir disoproxil can be decreased when combined with Riboflavin.
Indomethacin The excretion of Indomethacin can be decreased when combined with Riboflavin.
Aminohippuric acid The excretion of Aminohippuric acid can be decreased when combined with Riboflavin.
Grepafloxacin The excretion of Grepafloxacin can be decreased when combined with Riboflavin.
Cidofovir The excretion of Cidofovir can be decreased when combined with Riboflavin.
Trifluridine The excretion of Trifluridine can be decreased when combined with Riboflavin.
Zidovudine The excretion of Zidovudine can be decreased when combined with Riboflavin.
Cimetidine The excretion of Cimetidine can be decreased when combined with Riboflavin.
Cefdinir The excretion of Cefdinir can be decreased when combined with Riboflavin.
Cephalexin The excretion of Cephalexin can be decreased when combined with Riboflavin.
Stavudine The excretion of Stavudine can be decreased when combined with Riboflavin.
Fluorescein The excretion of Fluorescein can be decreased when combined with Riboflavin.
Lamivudine The excretion of Lamivudine can be decreased when combined with Riboflavin.
Adefovir dipivoxil The excretion of Adefovir dipivoxil can be decreased when combined with Riboflavin.
Acyclovir The excretion of Acyclovir can be decreased when combined with Riboflavin.
Ranitidine The excretion of Ranitidine can be decreased when combined with Riboflavin.
Didanosine The excretion of Didanosine can be decreased when combined with Riboflavin.
Dinoprostone The excretion of Dinoprostone can be decreased when combined with Riboflavin.
Zalcitabine The excretion of Zalcitabine can be decreased when combined with Riboflavin.
Levofloxacin The excretion of Levofloxacin can be decreased when combined with Riboflavin.
Captopril The excretion of Captopril can be decreased when combined with Riboflavin.
Cefazolin The excretion of Cefazolin can be decreased when combined with Riboflavin.
Ceftizoxime The excretion of Ceftizoxime can be decreased when combined with Riboflavin.
Cefacetrile The excretion of Cefacetrile can be decreased when combined with Riboflavin.
Ceftibuten The excretion of Ceftibuten can be decreased when combined with Riboflavin.
Tazobactam The excretion of Tazobactam can be decreased when combined with Riboflavin.
Cyclic adenosine monophosphate The excretion of Cyclic adenosine monophosphate can be decreased when combined with Riboflavin.
Glutaric Acid The excretion of Glutaric Acid can be decreased when combined with Riboflavin.
Taurocholic acid The excretion of Taurocholic acid can be decreased when combined with Riboflavin.
Ellagic acid The excretion of Ellagic acid can be decreased when combined with Riboflavin.
Cefaloridine The excretion of Cefaloridine can be decreased when combined with Riboflavin.
Tenofovir alafenamide The excretion of Tenofovir alafenamide can be decreased when combined with Riboflavin.
Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Riboflavin.
Padeliporfin Riboflavin may increase the photosensitizing activities of Padeliporfin.
Vadadustat The serum concentration of Vadadustat can be increased when it is combined with Riboflavin.
Sulbactam The excretion of Sulbactam can be decreased when combined with Riboflavin.
Acamprosate The excretion of Acamprosate can be decreased when combined with Riboflavin.

Target Protein

Riboflavin kinase RFK
Riboflavin synthase ribC
Flavin reductase (NADPH) BLVRB

Referensi & Sumber

Synthesis reference: Hansgeorg Ernst, Wolfram Schmidt, Joachim Paust, "Preparation of riboflavin." U.S. Patent US4567261, issued August, 1958.
Artikel (PubMed)
  • PMID: 8604671
    Zempleni J, Galloway JR, McCormick DB: Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans. Am J Clin Nutr. 1996 Jan;63(1):54-66.

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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