Peringatan Keamanan

Oral, rat LD50 = 10000 mg/kg

Ornithine

DB00129

small molecule approved nutraceutical

Deskripsi

Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.

Struktur Molekul 2D

Berat 132.161
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Absorbed from the small intestine via a sodium-dependent active transport process

Metabolisme

Ornithine undergoes extensive metabolism in the liver to L-arginine, polyamines, and proline, and several other metabolites.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

0 Data
Tidak ada data.

Target Protein

Ornithine aminotransferase, mitochondrial OAT
Ornithine transcarbamylase, mitochondrial OTC
Arginase-1 ARG1
Ornithine decarboxylase antizyme 1 OAZ1
High affinity cationic amino acid transporter 1 SLC7A1
Cationic amino acid transporter 2 SLC7A2
Mitochondrial ornithine transporter 2 SLC25A2
Arginase-2, mitochondrial ARG2
Mitochondrial ornithine transporter 1 SLC25A15
Glycine amidinotransferase, mitochondrial GATM

Referensi & Sumber

Synthesis reference: Takayasu Tsuchida, Haruo Uchibori, Yoshitaka Nishimoto, "Process and microorganism for producing L-ornithine by Corynebacterium, Brevibacterium, or Athrobacter." U.S. Patent US5188947, issued January, 1970.

Contoh Produk & Brand

Produk: 3 • International brands: 0
Produk
  • Primene
    Injection, solution • - • Intravenous • US
  • Primene 10%
    Liquid • - • Intravenous • Canada • Approved
  • Primene 10%-liq IV
    Liquid • - • Intravenous • Canada • Approved

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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