Spermine

DB00127

small molecule experimental nutraceutical

Deskripsi

Spermine is a spermidine-derived biogenic polyamine found as a polycation at all pH values. Found in various tissues and organisms, it often acts as an essential growth factor in some bacterial species. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.

Struktur Molekul 2D

Berat 202.3402
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

49 Data
Choline The risk or severity of adverse effects can be increased when Choline is combined with Spermine.
Nicotine The risk or severity of adverse effects can be increased when Nicotine is combined with Spermine.
Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Spermine.
Nelfinavir The risk or severity of adverse effects can be increased when Nelfinavir is combined with Spermine.
Indinavir The risk or severity of adverse effects can be increased when Indinavir is combined with Spermine.
Nevirapine The risk or severity of adverse effects can be increased when Nevirapine is combined with Spermine.
Disopyramide The risk or severity of adverse effects can be increased when Disopyramide is combined with Spermine.
Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Spermine.
Progesterone The risk or severity of adverse effects can be increased when Progesterone is combined with Spermine.
Prazosin The risk or severity of adverse effects can be increased when Prazosin is combined with Spermine.
Quinine The risk or severity of adverse effects can be increased when Quinine is combined with Spermine.
Cimetidine The risk or severity of adverse effects can be increased when Cimetidine is combined with Spermine.
Guanidine The risk or severity of adverse effects can be increased when Guanidine is combined with Spermine.
Doxazosin The risk or severity of adverse effects can be increased when Doxazosin is combined with Spermine.
Efavirenz The risk or severity of adverse effects can be increased when Efavirenz is combined with Spermine.
Verapamil The risk or severity of adverse effects can be increased when Verapamil is combined with Spermine.
Rocuronium The risk or severity of adverse effects can be increased when Rocuronium is combined with Spermine.
Clopidogrel The risk or severity of adverse effects can be increased when Clopidogrel is combined with Spermine.
Acyclovir The risk or severity of adverse effects can be increased when Acyclovir is combined with Spermine.
Quinidine The risk or severity of adverse effects can be increased when Quinidine is combined with Spermine.
Phenformin The risk or severity of adverse effects can be increased when Phenformin is combined with Spermine.
Amantadine The risk or severity of adverse effects can be increased when Amantadine is combined with Spermine.
Dinoprostone The risk or severity of adverse effects can be increased when Dinoprostone is combined with Spermine.
Phenoxybenzamine The risk or severity of adverse effects can be increased when Phenoxybenzamine is combined with Spermine.
Ganciclovir The risk or severity of adverse effects can be increased when Ganciclovir is combined with Spermine.
Probenecid The risk or severity of adverse effects can be increased when Probenecid is combined with Spermine.
Procainamide The risk or severity of adverse effects can be increased when Procainamide is combined with Spermine.
Chlorpheniramine The risk or severity of adverse effects can be increased when Chlorpheniramine is combined with Spermine.
Desipramine The risk or severity of adverse effects can be increased when Desipramine is combined with Spermine.
Saquinavir The risk or severity of adverse effects can be increased when Saquinavir is combined with Spermine.
Pancuronium The risk or severity of adverse effects can be increased when Pancuronium is combined with Spermine.
Linagliptin The risk or severity of adverse effects can be increased when Linagliptin is combined with Spermine.
Palbociclib The risk or severity of adverse effects can be increased when Palbociclib is combined with Spermine.
Dexchlorpheniramine maleate The risk or severity of adverse effects can be increased when Dexchlorpheniramine maleate is combined with Spermine.
Pitolisant The risk or severity of adverse effects can be increased when Pitolisant is combined with Spermine.
Dacomitinib The risk or severity of adverse effects can be increased when Dacomitinib is combined with Spermine.
Gilteritinib The risk or severity of adverse effects can be increased when Gilteritinib is combined with Spermine.
Estradiol acetate The risk or severity of adverse effects can be increased when Estradiol acetate is combined with Spermine.
Estradiol benzoate The risk or severity of adverse effects can be increased when Estradiol benzoate is combined with Spermine.
Estradiol cypionate The risk or severity of adverse effects can be increased when Estradiol cypionate is combined with Spermine.
Estradiol dienanthate The risk or severity of adverse effects can be increased when Estradiol dienanthate is combined with Spermine.
Estradiol valerate The risk or severity of adverse effects can be increased when Estradiol valerate is combined with Spermine.
Choline salicylate The risk or severity of adverse effects can be increased when Choline salicylate is combined with Spermine.
Dronedarone The risk or severity of adverse effects can be increased when Dronedarone is combined with Spermine.
Formoterol The risk or severity of adverse effects can be increased when Formoterol is combined with Spermine.
Guanfacine The risk or severity of adverse effects can be increased when Guanfacine is combined with Spermine.
Salmeterol The risk or severity of adverse effects can be increased when Salmeterol is combined with Spermine.
Ranitidine The risk or severity of adverse effects can be increased when Ranitidine is combined with Spermine.
Pacritinib The serum concentration of Spermine can be increased when it is combined with Pacritinib.

Target Protein

Spermine synthase SMS
Carbonic anhydrase 4 CA4
Glutamate receptor ionotropic, NMDA 1 GRIN1
Carbonic anhydrase 9 CA9
Carbonic anhydrase 6 CA6
Carbonic anhydrase 14 CA14
Glutamate receptor ionotropic, NMDA 2A GRIN2A
Spermine oxidase SMOX
DNA
Ornithine decarboxylase ODC1
Extracellular calcium-sensing receptor CASR
Beta-1 adrenergic receptor ADRB1
Beta-2 adrenergic receptor ADRB2

Referensi & Sumber

Synthesis reference: Koji Nakanishi, Amira T. Eldefrawi, Mohyee E. Eldefrawi, Peter N. R. Usherwood, "Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same." U.S. Patent US5770625, issued January, 1966.

Contoh Produk & Brand

Produk: 0 • International brands: 0
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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