Digoxin Immune Fab (Ovine)

DB00076

biotech approved

Deskripsi

Digoxin Immune Fab is a sheep antibody (26-10) FAB fragment from sheep immunized with the digoxin derivative Digoxindicarboxymethylamine. It is used as an antidote for overdose of digoxin.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 15-20 hrs
Volume Distribusi * 0.3 L/kg [DigiFab] * 0.4 L/kg [Digibind]
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Cumulative urinary excretion of digoxin was comparable for both products and exceeded 40% of the administered dose by 24 hours.

Interaksi Obat

372 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Estrone Estrone may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Estradiol Estradiol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Dienestrol Dienestrol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Mestranol Mestranol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Estriol Estriol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Quinestrol Quinestrol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Hexestrol Hexestrol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Tibolone Tibolone may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Zeranol Zeranol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Equol Equol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Promestriene Promestriene may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Methallenestril Methallenestril may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Epimestrol Epimestrol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Moxestrol Moxestrol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Biochanin A Biochanin A may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Formononetin Formononetin may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Estetrol Estetrol may increase the thrombogenic activities of Digoxin Immune Fab (Ovine).
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Digoxin Immune Fab (Ovine).
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Digoxin Immune Fab (Ovine).
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Digoxin Immune Fab (Ovine).
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Digoxin Immune Fab (Ovine).
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Digoxin Immune Fab (Ovine).
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Digoxin Immune Fab (Ovine).
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Digoxin Immune Fab (Ovine).
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Digoxin Immune Fab (Ovine).
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Digoxin Immune Fab (Ovine).
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Digoxin Immune Fab (Ovine).
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Digoxin Immune Fab (Ovine).
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Digoxin Immune Fab (Ovine).
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Ibritumomab tiuxetan.
Tositumomab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Tositumomab.
Alemtuzumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Alemtuzumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Capromab pendetide.
Efalizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Efalizumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Antithymocyte immunoglobulin (rabbit).
Natalizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Natalizumab.
Palivizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Palivizumab.
Daclizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Daclizumab.
Bevacizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Bevacizumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Technetium Tc-99m arcitumomab.
Eculizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Eculizumab.
Panitumumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Panitumumab.
Ranibizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Ranibizumab.
Galiximab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Galiximab.
Pexelizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Pexelizumab.
Afelimomab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Afelimomab.
Epratuzumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Epratuzumab.
Bectumomab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Bectumomab.
Oregovomab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Oregovomab.
IGN311 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with IGN311.
Adecatumumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Adecatumumab.
Labetuzumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Labetuzumab.
Matuzumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Matuzumab.
Fontolizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Fontolizumab.
Bavituximab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Bavituximab.
CR002 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with CR002.
Rozrolimupab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Rozrolimupab.
Girentuximab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Girentuximab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Obiltoxaximab.
XTL-001 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with XTL-001.
NAV 1800 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with NAV 1800.
Briakinumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Briakinumab.
Otelixizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Otelixizumab.
AMG 108 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with AMG 108.
Iratumumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Iratumumab.
Enokizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Enokizumab.
Ramucirumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Ramucirumab.
Farletuzumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Farletuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Veltuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Ustekinumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Trastuzumab emtansine.
PRO-542 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with PRO-542.
TNX-901 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with TNX-901.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Inotuzumab ozogamicin.
RI 624 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with RI 624.
Stamulumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with MYO-029.
CT-011 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with CT-011.
Leronlimab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Leronlimab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Canakinumab.

Target Protein

Digoxin

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 5 • International brands: 0
Produk
  • Digibind
    Injection, powder, for solution • 38 mg/1 • Intravenous • US • Approved
  • Digibind
    Powder, for solution • 38 mg / vial • Intravenous • Canada • Approved
  • DigiFab
    Injection, powder, for solution • 40 mg/1 • Intravenous • US • Approved
  • DigiFab
    Injection, powder, lyophilized, for solution • 38 mg/1 • Intravenous • US • Approved
  • DigiFab
    Powder, for solution • 40 mg / vial • Intravenous • Canada • Approved

Sekuens Gen/Protein (FASTA)

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