Hyaluronidase (ovine)

DB00070

biotech approved investigational

Deskripsi

Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

204 Data
Dopamine The risk or severity of adverse effects can be increased when Hyaluronidase (ovine) is combined with Dopamine.
Betamethasone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Betamethasone.
Fluocinolone acetonide The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Fluocinolone acetonide.
Triamcinolone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Triamcinolone.
Hydrocortisone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Hydrocortisone.
Methylprednisolone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Methylprednisolone.
Trilostane The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Trilostane.
Dexamethasone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Dexamethasone.
Corticotropin The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Corticotropin.
Cortisone acetate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Cortisone acetate.
Paramethasone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Paramethasone.
Aldosterone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Aldosterone.
Fluprednidene The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Fluprednidene.
Fluprednisolone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Fluprednisolone.
Meprednisone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Meprednisone.
Dexamethasone isonicotinate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Dexamethasone isonicotinate.
Melengestrol The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Melengestrol.
Cortivazol The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Cortivazol.
Prednylidene The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Prednylidene.
Fluocortin The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Fluocortin.
Fluperolone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Fluperolone.
Fluclorolone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Fluclorolone.
Hydrocortisone succinate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Hydrocortisone succinate.
Prednisolone hemisuccinate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Prednisolone hemisuccinate.
Methylprednisolone hemisuccinate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Methylprednisolone hemisuccinate.
Prednisone acetate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Prednisone acetate.
Clocortolone acetate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Clocortolone acetate.
Melengestrol acetate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Melengestrol acetate.
Betamethasone phosphate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Betamethasone phosphate.
Prednisolone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Prednisolone.
Clobetasol propionate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Clobetasol propionate.
Prednisolone acetate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Prednisolone acetate.
Fluorometholone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Fluorometholone.
Cloprednol The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Cloprednol.
Salicylic acid The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Salicylic acid.
Dersalazine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Dersalazine.
Phenyl aminosalicylate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Phenyl aminosalicylate.
Nitroaspirin The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Nitroaspirin.
Aloxiprin The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Aloxiprin.
Guacetisal The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Guacetisal.
Thiosalicylic acid The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Thiosalicylic acid.
Acetylsalicylic acid The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Acetylsalicylic acid.
Lidocaine Hyaluronidase (ovine) can cause an increase in the absorption of Lidocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Bupivacaine Hyaluronidase (ovine) can cause an increase in the absorption of Bupivacaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Cinchocaine Hyaluronidase (ovine) can cause an increase in the absorption of Cinchocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Dyclonine Hyaluronidase (ovine) can cause an increase in the absorption of Dyclonine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Prilocaine Hyaluronidase (ovine) can cause an increase in the absorption of Prilocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Proparacaine Hyaluronidase (ovine) can cause an increase in the absorption of Proparacaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Oxybuprocaine Hyaluronidase (ovine) can cause an increase in the absorption of Oxybuprocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Mepivacaine Hyaluronidase (ovine) can cause an increase in the absorption of Mepivacaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Benzocaine Hyaluronidase (ovine) can cause an increase in the absorption of Benzocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Tetrodotoxin Hyaluronidase (ovine) can cause an increase in the absorption of Tetrodotoxin resulting in an increased serum concentration and potentially a worsening of adverse effects.
Benzyl alcohol Hyaluronidase (ovine) can cause an increase in the absorption of Benzyl alcohol resulting in an increased serum concentration and potentially a worsening of adverse effects.
Etidocaine Hyaluronidase (ovine) can cause an increase in the absorption of Etidocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Articaine Hyaluronidase (ovine) can cause an increase in the absorption of Articaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Tetracaine Hyaluronidase (ovine) can cause an increase in the absorption of Tetracaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Butamben Hyaluronidase (ovine) can cause an increase in the absorption of Butamben resulting in an increased serum concentration and potentially a worsening of adverse effects.
Butacaine Hyaluronidase (ovine) can cause an increase in the absorption of Butacaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Butanilicaine Hyaluronidase (ovine) can cause an increase in the absorption of Butanilicaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Metabutethamine Hyaluronidase (ovine) can cause an increase in the absorption of Metabutethamine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Quinisocaine Hyaluronidase (ovine) can cause an increase in the absorption of Quinisocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Propoxycaine Hyaluronidase (ovine) can cause an increase in the absorption of Propoxycaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Procaine Hyaluronidase (ovine) can cause an increase in the absorption of Procaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Phenol Hyaluronidase (ovine) can cause an increase in the absorption of Phenol resulting in an increased serum concentration and potentially a worsening of adverse effects.
Benzatropine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Benzatropine.
Ziprasidone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Ziprasidone.
Cetirizine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Cetirizine.
Promazine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Promazine.
Imipramine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Imipramine.
Chlorpromazine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Chlorpromazine.
Cimetidine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Cimetidine.
Hydroxyzine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Hydroxyzine.
Risperidone The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Risperidone.
Benzquinamide The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Benzquinamide.
Propiomazine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Propiomazine.
Brompheniramine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Brompheniramine.
Ranitidine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Ranitidine.
Methdilazine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Methdilazine.
Famotidine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Famotidine.
Methantheline The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Methantheline.
Azelastine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Azelastine.
Dimenhydrinate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Dimenhydrinate.
Promethazine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Promethazine.
Diphenhydramine Hyaluronidase (ovine) can cause an increase in the absorption of Diphenhydramine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Chlorpheniramine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Chlorpheniramine.
Orphenadrine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Orphenadrine.
Cyclizine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Cyclizine.
Aripiprazole The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Aripiprazole.
Methotrimeprazine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Methotrimeprazine.
Aceprometazine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Aceprometazine.
Phenindamine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Phenindamine.
Zuclopenthixol The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Zuclopenthixol.
Methapyrilene The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Methapyrilene.
Esmirtazapine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Esmirtazapine.
Chloropyramine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Chloropyramine.
Metiamide The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Metiamide.
Roxatidine acetate The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Roxatidine acetate.
Dimetotiazine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Dimetotiazine.
Butriptyline The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Butriptyline.
Lafutidine The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Lafutidine.

Target Protein

Transforming growth factor beta-1 proprotein TGFB1

Referensi & Sumber

Synthesis reference: Yasuhiro Mima, Masaaki Yamada, "Preparation of human placental hyaluronidase." U.S. Patent US3945889, issued October, 1957.
Artikel (PubMed)
  • PMID: 10493834
    Csoka AB, Scherer SW, Stern R: Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31. Genomics. 1999 Sep 15;60(3):356-61.

Contoh Produk & Brand

Produk: 3 • International brands: 4
Produk
  • Vitrase
    Injection, powder, lyophilized, for solution • 6200 [USP'U]/5mL • Subcutaneous • US • Approved
  • Vitrase
    Injection, solution • 200 [USP'U]/1mL • Subcutaneous • US • Approved
  • Vitrase
    Injection, solution • 200 [USP'U]/1mL • Subcutaneous • US • Approved
International Brands
  • Diffusin
  • Enzodase
  • Hyazyme
  • Wydase

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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