Indium In-111 satumomab pendetide

DB00057

biotech experimental withdrawn

Deskripsi

Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 0.8 hours (mammalian reticulocytes, in vitro)
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Most likely removed by opsonization via the reticuloendothelial system or by human antimurine antibody production

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

372 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Estrone Estrone may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Estradiol Estradiol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Dienestrol Dienestrol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Mestranol Mestranol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Estriol Estriol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Quinestrol Quinestrol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Hexestrol Hexestrol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Tibolone Tibolone may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Zeranol Zeranol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Equol Equol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Promestriene Promestriene may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Methallenestril Methallenestril may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Epimestrol Epimestrol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Moxestrol Moxestrol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Biochanin A Biochanin A may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Formononetin Formononetin may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Estetrol Estetrol may increase the thrombogenic activities of Indium In-111 satumomab pendetide.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Indium In-111 satumomab pendetide.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Indium In-111 satumomab pendetide.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Indium In-111 satumomab pendetide.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Indium In-111 satumomab pendetide.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Indium In-111 satumomab pendetide.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Indium In-111 satumomab pendetide.
Infliximab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Infliximab.
Trastuzumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Trastuzumab.
Rituximab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Rituximab.
Basiliximab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Basiliximab.
Muromonab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Muromonab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Digoxin Immune Fab (Ovine).
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Ibritumomab tiuxetan.
Tositumomab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Tositumomab.
Alemtuzumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Alemtuzumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Capromab pendetide.
Efalizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Efalizumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Antithymocyte immunoglobulin (rabbit).
Natalizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Natalizumab.
Palivizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Palivizumab.
Daclizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Daclizumab.
Bevacizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Bevacizumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Technetium Tc-99m arcitumomab.
Eculizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Eculizumab.
Panitumumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Panitumumab.
Ranibizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Ranibizumab.
Galiximab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Galiximab.
Pexelizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Pexelizumab.
Afelimomab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Afelimomab.
Epratuzumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Epratuzumab.
Bectumomab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Bectumomab.
Oregovomab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Oregovomab.
IGN311 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with IGN311.
Adecatumumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Adecatumumab.
Labetuzumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Labetuzumab.
Matuzumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Matuzumab.
Fontolizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Fontolizumab.
Bavituximab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Bavituximab.
CR002 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with CR002.
Rozrolimupab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Rozrolimupab.
Girentuximab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Girentuximab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Obiltoxaximab.
XTL-001 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with XTL-001.
NAV 1800 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with NAV 1800.
Briakinumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Briakinumab.
Otelixizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Otelixizumab.
AMG 108 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with AMG 108.
Iratumumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Iratumumab.
Enokizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Enokizumab.
Ramucirumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Ramucirumab.
Farletuzumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Farletuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Veltuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Ustekinumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Trastuzumab emtansine.
PRO-542 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with PRO-542.
TNX-901 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with TNX-901.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Inotuzumab ozogamicin.
RI 624 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with RI 624.
Stamulumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with MYO-029.
CT-011 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with CT-011.
Leronlimab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Leronlimab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Glembatumumab vedotin.
Olaratumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Olaratumab.
IPH 2101 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with IPH 2101.
TB-402 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with TB-402.
Caplacizumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Caplacizumab.
IMC-1C11 The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with IMC-1C11.
Eldelumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Eldelumab.
Lumiliximab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Lumiliximab.
Canakinumab The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Canakinumab.

Target Protein

Tumor-associated glycoprotein 72 (TAG-72)

Referensi & Sumber

Artikel (PubMed)
  • PMID: 12845972
    Artiko V, Obradovic V, Davidovic B, Petrovic N, Petrovic M, Krivokapic Z, Kecmanovic D, Pesko P, Djukic V, Milosavljevic T, Adanja G, Vlajkovic M: Radioimmunodetection of colorectal carcinoma. Hepatogastroenterology. 2003 Jul-Aug;50(52):1029-31.
  • PMID: 9755434
    Bohdiewicz PJ: Indium-111 satumomab pendetide: the first FDA-approved monoclonal antibody for tumor imaging. J Nucl Med Technol. 1998 Sep;26(3):155-63; quiz 170-1.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • OncoScint — Cytogen Corp, Lonza Biologics

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul