Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Prilocaine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Prilocaine. |
| Dapsone | The risk or severity of methemoglobinemia can be increased when Dapsone is combined with Rasburicase. |
| Aminosalicylic acid | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Aminosalicylic acid. |
| Butalbital | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Butalbital. |
| Phenytoin | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Phenytoin. |
| Lidocaine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Lidocaine. |
| Ropivacaine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Ropivacaine. |
| Bupivacaine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Bupivacaine. |
| Valproic acid | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Valproic acid. |
| Acetaminophen | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Acetaminophen. |
| Nitroprusside | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Nitroprusside. |
| Sulfadiazine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Sulfadiazine. |
| Nitric Oxide | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Nitric Oxide. |
| Quinine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Quinine. |
| Celecoxib | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Celecoxib. |
| Flutamide | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Flutamide. |
| Cyclophosphamide | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Cyclophosphamide. |
| Chloroquine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Chloroquine. |
| Nitrofurantoin | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Nitrofurantoin. |
| Procaine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Procaine. |
| Nitroglycerin | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Nitroglycerin. |
| Sulfasalazine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Sulfasalazine. |
| Isosorbide dinitrate | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Isosorbide dinitrate. |
| Sulfapyridine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Sulfapyridine. |
| Mepivacaine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Mepivacaine. |
| Hydroxyurea | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Hydroxyurea. |
| Sulfamethoxazole | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Sulfamethoxazole. |
| Isosorbide mononitrate | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Isosorbide mononitrate. |
| Benzocaine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Benzocaine. |
| Primaquine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Primaquine. |
| Phenobarbital | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Phenobarbital. |
| Ifosfamide | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Ifosfamide. |
| Zopiclone | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Zopiclone. |
| Metoclopramide | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Metoclopramide. |
| Antipyrine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Antipyrine. |
| Phenazopyridine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Phenazopyridine. |
| Amyl Nitrite | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Amyl Nitrite. |
| Nitrous oxide | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Nitrous oxide. |
| Isometheptene | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Isometheptene. |
| Articaine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Articaine. |
| Tetracaine | The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Tetracaine. |
| Methyclothiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Methyclothiazide. |
| Bendroflumethiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Bendroflumethiazide. |
| Benzthiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Benzthiazide. |
| Cyclothiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Cyclothiazide. |
| Hydroflumethiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Hydroflumethiazide. |
| Chlorothiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Chlorothiazide. |
| Hydrochlorothiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Hydrochlorothiazide. |
| Trichlormethiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Trichlormethiazide. |
| Polythiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Polythiazide. |
| Mebutizide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Mebutizide. |
| Cyclopenthiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Cyclopenthiazide. |
| Buthiazide | The therapeutic efficacy of Rasburicase can be decreased when used in combination with Buthiazide. |