Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography.
The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray et. al. and not specifically interferon gamma 1b.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Denosumab | The risk or severity of adverse effects can be increased when Denosumab is combined with Interferon gamma-1b. |
| Etanercept | The risk or severity of adverse effects can be increased when Etanercept is combined with Interferon gamma-1b. |
| Peginterferon alfa-2a | The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Interferon gamma-1b. |
| Interferon alfa-n1 | The risk or severity of adverse effects can be increased when Interferon alfa-n1 is combined with Interferon gamma-1b. |
| Interferon alfa-n3 | The risk or severity of adverse effects can be increased when Interferon alfa-n3 is combined with Interferon gamma-1b. |
| Peginterferon alfa-2b | The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Interferon gamma-1b. |
| Anakinra | The risk or severity of adverse effects can be increased when Anakinra is combined with Interferon gamma-1b. |
| Interferon alfa-2a | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Interferon alfa-2a. |
| Aldesleukin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Aldesleukin. |
| Adalimumab | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Adalimumab. |
| Gemtuzumab ozogamicin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Gemtuzumab ozogamicin. |
| Pegaspargase | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Pegaspargase. |
| Infliximab | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Infliximab. |
| Interferon beta-1b | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Interferon beta-1b. |
| Interferon alfacon-1 | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Interferon alfacon-1. |
| Rituximab | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Rituximab. |
| Basiliximab | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Basiliximab. |
| Muromonab | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Muromonab. |
| Ibritumomab tiuxetan | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Ibritumomab tiuxetan. |
| Tositumomab | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Tositumomab. |
| Alemtuzumab | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Alemtuzumab. |
| Alefacept | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Alefacept. |
| Efalizumab | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Efalizumab. |
| Antithymocyte immunoglobulin (rabbit) | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Antithymocyte immunoglobulin (rabbit). |
| Interferon alfa-2b | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Interferon alfa-2b. |
| Daclizumab | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Daclizumab. |
| Phenylalanine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Phenylalanine. |
| Flunisolide | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Flunisolide. |
| Bortezomib | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Bortezomib. |
| Cladribine | Interferon gamma-1b may increase the immunosuppressive activities of Cladribine. |
| Carmustine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Carmustine. |
| Amsacrine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Amsacrine. |
| Bleomycin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Bleomycin. |
| Chlorambucil | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Chlorambucil. |
| Raltitrexed | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Raltitrexed. |
| Mitomycin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Mitomycin. |
| Bexarotene | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Bexarotene. |
| Vindesine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Vindesine. |
| Floxuridine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Floxuridine. |
| Indomethacin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Indomethacin. |
| Tioguanine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Tioguanine. |
| Vinorelbine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Vinorelbine. |
| Dexrazoxane | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Dexrazoxane. |
| Beclomethasone dipropionate | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Beclomethasone dipropionate. |
| Sorafenib | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Sorafenib. |
| Streptozocin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Streptozocin. |
| Trifluridine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Trifluridine. |
| Gemcitabine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Gemcitabine. |
| Betamethasone | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Betamethasone. |
| Teniposide | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Teniposide. |
| Epirubicin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Epirubicin. |
| Chloramphenicol | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Chloramphenicol. |
| Lenalidomide | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Lenalidomide. |
| Altretamine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Altretamine. |
| Zidovudine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Zidovudine. |
| Cisplatin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Cisplatin. |
| Oxaliplatin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Oxaliplatin. |
| Cyclophosphamide | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Cyclophosphamide. |
| Vincristine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Vincristine. |
| Fluorouracil | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Fluorouracil. |
| Propylthiouracil | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Propylthiouracil. |
| Pentostatin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Pentostatin. |
| Methotrexate | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Methotrexate. |
| Carbamazepine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Carbamazepine. |
| Vinblastine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Vinblastine. |
| Fluticasone propionate | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Fluticasone propionate. |
| Fluocinolone acetonide | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Fluocinolone acetonide. |
| Linezolid | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Linezolid. |
| Imatinib | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Imatinib. |
| Triamcinolone | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Triamcinolone. |
| Clofarabine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Clofarabine. |
| Prednisone | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Prednisone. |
| Pemetrexed | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Pemetrexed. |
| Fludrocortisone | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Fludrocortisone. |
| Mycophenolate mofetil | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Mycophenolate mofetil. |
| Daunorubicin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Daunorubicin. |
| Irinotecan | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Irinotecan. |
| Methimazole | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Methimazole. |
| Etoposide | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Etoposide. |
| Sulfasalazine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Sulfasalazine. |
| Dacarbazine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Dacarbazine. |
| Temozolomide | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Temozolomide. |
| Penicillamine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Penicillamine. |
| Prednisolone | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Prednisolone. |
| Sirolimus | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Sirolimus. |
| Mechlorethamine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Mechlorethamine. |
| Azacitidine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Azacitidine. |
| Carboplatin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Carboplatin. |
| Methylprednisolone | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Methylprednisolone. |
| Dactinomycin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Dactinomycin. |
| Cytarabine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Cytarabine. |
| Azathioprine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Azathioprine. |
| Doxorubicin | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Doxorubicin. |
| Hydroxyurea | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Hydroxyurea. |
| Busulfan | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Busulfan. |
| Mycophenolic acid | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Mycophenolic acid. |
| Topotecan | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Topotecan. |
| Mercaptopurine | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Mercaptopurine. |
| Thalidomide | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Thalidomide. |
| Melphalan | The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Melphalan. |