Salmon calcitonin was shown to inhibit lactation in animals and is not recommend in nursing mothers. While research in animals have shown a decrease in fetal weight, no studies have yet shown similar results in humans. It is recommended however to proceed carefully when administering salmon calcitonin to pregnant women and consider if the benefits outweigh the risks. Because of its protein nature, salmon calcitonin may provoke an allergy reaction (bronchospams and swelling of the tongue/throat) that can turn into a full-blown anaphylactic response. The manufacturer also reports an increase in the risk of malignancies from oral route (0.7%) to intranasal route (2.4%) compared to placebo. The same may apply to IV, IM and SC routes since the systemic exposure is higher in those cases.
Nausea is noticeable in some patients but tends to decrease with continued administration. Rhinitis, headaches and back pain have also been reported among others.
Synthetic peptide, 32 residues long formulated as a nasal spray.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Citalopram | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Citalopram. |
| Fluoxetine | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Fluoxetine. |
| Trazodone | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Trazodone. |
| Sertraline | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Sertraline. |
| Escitalopram | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Escitalopram. |
| Zimelidine | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Zimelidine. |
| Dapoxetine | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Dapoxetine. |
| Seproxetine | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Seproxetine. |
| Indalpine | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Indalpine. |
| Ritanserin | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Ritanserin. |
| Alaproclate | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Alaproclate. |
| Paroxetine | The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Paroxetine. |
| Zoledronic acid | The risk or severity of hypocalcemia can be increased when Salmon calcitonin is combined with Zoledronic acid. |
| Alendronic acid | The risk or severity of hypocalcemia can be increased when Salmon calcitonin is combined with Alendronic acid. |
| Ibandronate | The risk or severity of hypocalcemia can be increased when Salmon calcitonin is combined with Ibandronate. |
| Clodronic acid | The risk or severity of hypocalcemia can be increased when Salmon calcitonin is combined with Clodronic acid. |
| Risedronic acid | The risk or severity of hypocalcemia can be increased when Salmon calcitonin is combined with Risedronic acid. |
| Etidronic acid | The risk or severity of hypocalcemia can be increased when Salmon calcitonin is combined with Etidronic acid. |
| Incadronic acid | The risk or severity of hypocalcemia can be increased when Salmon calcitonin is combined with Incadronic acid. |
| Pamidronic acid | The risk or severity of hypocalcemia can be increased when Salmon calcitonin is combined with Pamidronic acid. |
| Tiludronic acid | The risk or severity of hypocalcemia can be increased when Salmon calcitonin is combined with Tiludronic acid. |
| Lithium citrate | Salmon calcitonin may increase the excretion rate of Lithium citrate which could result in a lower serum level and potentially a reduction in efficacy. |
| Lithium carbonate | Salmon calcitonin may increase the excretion rate of Lithium carbonate which could result in a lower serum level and potentially a reduction in efficacy. |
| Lithium hydroxide | Salmon calcitonin may increase the excretion rate of Lithium hydroxide which could result in a lower serum level and potentially a reduction in efficacy. |
| Cyclosporine | Cyclosporine may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Icosapent | Icosapent may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefotiam | Cefotiam may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Mesalazine | Mesalazine may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefmenoxime | Cefmenoxime may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefmetazole | Cefmetazole may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Tenofovir disoproxil | Tenofovir disoproxil may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Indomethacin | Indomethacin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cidofovir | Cidofovir may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefpiramide | Cefpiramide may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Ceftazidime | Ceftazidime may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Loracarbef | Loracarbef may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefalotin | Cefalotin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Nabumetone | Nabumetone may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Ketorolac | Ketorolac may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Tenoxicam | Tenoxicam may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Celecoxib | Celecoxib may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefotaxime | Cefotaxime may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Tolmetin | Tolmetin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Foscarnet | Foscarnet may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Rofecoxib | Rofecoxib may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Piroxicam | Piroxicam may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Methotrexate | Methotrexate may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cephalexin | Cephalexin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Fenoprofen | Fenoprofen may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Valaciclovir | Valaciclovir may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Valdecoxib | Valdecoxib may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Diclofenac | Diclofenac may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Sulindac | Sulindac may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Bacitracin | Bacitracin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Amphotericin B | Amphotericin B may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cephaloglycin | Cephaloglycin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Flurbiprofen | Flurbiprofen may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Adefovir dipivoxil | Adefovir dipivoxil may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Pentamidine | Pentamidine may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Etodolac | Etodolac may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Mefenamic acid | Mefenamic acid may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Acyclovir | Acyclovir may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Naproxen | Naproxen may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Sulfasalazine | Sulfasalazine may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Phenylbutazone | Phenylbutazone may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Meloxicam | Meloxicam may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Carprofen | Carprofen may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefaclor | Cefaclor may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Diflunisal | Diflunisal may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Tacrolimus | Tacrolimus may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Ceforanide | Ceforanide may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Salicylic acid | Salicylic acid may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Meclofenamic acid | Meclofenamic acid may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Acetylsalicylic acid | Acetylsalicylic acid may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Carboplatin | Carboplatin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Oxaprozin | Oxaprozin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Ketoprofen | Ketoprofen may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Balsalazide | Balsalazide may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Ibuprofen | Ibuprofen may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefditoren | Cefditoren may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Atazanavir | Atazanavir may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Colistimethate | Colistimethate may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefuroxime | Cefuroxime may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefapirin | Cefapirin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefadroxil | Cefadroxil may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefprozil | Cefprozil may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Ceftriaxone | Ceftriaxone may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Olsalazine | Olsalazine may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Lumiracoxib | Lumiracoxib may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefamandole | Cefamandole may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefazolin | Cefazolin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefonicid | Cefonicid may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefoperazone | Cefoperazone may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefotetan | Cefotetan may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefoxitin | Cefoxitin may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Ceftizoxime | Ceftizoxime may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Cefradine | Cefradine may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Magnesium salicylate | Magnesium salicylate may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Salsalate | Salsalate may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |
| Choline magnesium trisalicylate | Choline magnesium trisalicylate may decrease the excretion rate of Salmon calcitonin which could result in a higher serum level. |