Patients experiencing an overdose may present with bleeding.L12141 Treat patients with symptomatic and supportive measures which may include application of local pressure, administration of whole blood or plasma, and administration of aminocaproic acid.L12141
Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase.A191943 Urokinase remains connected between these 2 chains by a sulfhydryl bond.A191943
Urokinase was granted FDA approval on 16 January 1978.L12138
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Apixaban | Apixaban may increase the anticoagulant activities of Urokinase. |
| Dabigatran etexilate | Dabigatran etexilate may increase the anticoagulant activities of Urokinase. |
| Dasatinib | The risk or severity of bleeding and hemorrhage can be increased when Dasatinib is combined with Urokinase. |
| Deferasirox | The risk or severity of gastrointestinal bleeding can be increased when Urokinase is combined with Deferasirox. |
| Ursodeoxycholic acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Ursodeoxycholic acid. |
| Glycochenodeoxycholic Acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Glycochenodeoxycholic Acid. |
| Cholic Acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Cholic Acid. |
| Glycocholic acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Glycocholic acid. |
| Deoxycholic acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Deoxycholic acid. |
| Taurocholic acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Taurocholic acid. |
| Obeticholic acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Obeticholic acid. |
| Chenodeoxycholic acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Chenodeoxycholic acid. |
| Taurochenodeoxycholic acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Taurochenodeoxycholic acid. |
| Tauroursodeoxycholic acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Tauroursodeoxycholic acid. |
| Bamet-UD2 | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Bamet-UD2. |
| Dehydrocholic acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Dehydrocholic acid. |
| Hyodeoxycholic Acid | The risk or severity of bleeding and bruising can be increased when Urokinase is combined with Hyodeoxycholic Acid. |
| Edoxaban | The risk or severity of bleeding can be increased when Edoxaban is combined with Urokinase. |
| Ibrutinib | The risk or severity of bleeding and hemorrhage can be increased when Ibrutinib is combined with Urokinase. |
| Obinutuzumab | The risk or severity of bleeding and hemorrhage can be increased when Urokinase is combined with Obinutuzumab. |
| Rivaroxaban | Urokinase may increase the anticoagulant activities of Rivaroxaban. |
| Sugammadex | The risk or severity of bleeding and hemorrhage can be increased when Urokinase is combined with Sugammadex. |
| Tibolone | Tibolone may increase the anticoagulant activities of Urokinase. |
| Tipranavir | The risk or severity of bleeding and hemorrhage can be increased when Tipranavir is combined with Urokinase. |
| Lepirudin | Urokinase may increase the anticoagulant activities of Lepirudin. |
| Bivalirudin | Urokinase may increase the anticoagulant activities of Bivalirudin. |
| Alteplase | Urokinase may increase the anticoagulant activities of Alteplase. |
| Reteplase | Urokinase may increase the anticoagulant activities of Reteplase. |
| Anistreplase | Urokinase may increase the anticoagulant activities of Anistreplase. |
| Tenecteplase | Urokinase may increase the anticoagulant activities of Tenecteplase. |
| Abciximab | Urokinase may increase the anticoagulant activities of Abciximab. |
| Drotrecogin alfa | Urokinase may increase the anticoagulant activities of Drotrecogin alfa. |
| Streptokinase | Urokinase may increase the anticoagulant activities of Streptokinase. |
| Dicoumarol | Urokinase may increase the anticoagulant activities of Dicoumarol. |
| Argatroban | Urokinase may increase the anticoagulant activities of Argatroban. |
| Ardeparin | Urokinase may increase the anticoagulant activities of Ardeparin. |
| Phenindione | Urokinase may increase the anticoagulant activities of Phenindione. |
| Fondaparinux | Urokinase may increase the anticoagulant activities of Fondaparinux. |
| Warfarin | Urokinase may increase the anticoagulant activities of Warfarin. |
| Pentosan polysulfate | Urokinase may increase the anticoagulant activities of Pentosan polysulfate. |
| Phenprocoumon | Urokinase may increase the anticoagulant activities of Phenprocoumon. |
| Dipyridamole | Urokinase may increase the anticoagulant activities of Dipyridamole. |
| Heparin | Urokinase may increase the anticoagulant activities of Heparin. |
| Enoxaparin | Urokinase may increase the anticoagulant activities of Enoxaparin. |
| Epoprostenol | Urokinase may increase the anticoagulant activities of Epoprostenol. |
| Acenocoumarol | Urokinase may increase the anticoagulant activities of Acenocoumarol. |
| 4-hydroxycoumarin | Urokinase may increase the anticoagulant activities of 4-hydroxycoumarin. |
| Coumarin | Urokinase may increase the anticoagulant activities of Coumarin. |
| Ximelagatran | Urokinase may increase the anticoagulant activities of Ximelagatran. |
| Desmoteplase | Urokinase may increase the anticoagulant activities of Desmoteplase. |
| Defibrotide | Urokinase may increase the anticoagulant activities of Defibrotide. |
| Ancrod | Urokinase may increase the anticoagulant activities of Ancrod. |
| Beraprost | Urokinase may increase the anticoagulant activities of Beraprost. |
| Prasugrel | Urokinase may increase the anticoagulant activities of Prasugrel. |
| Sulodexide | Urokinase may increase the anticoagulant activities of Sulodexide. |
| Semuloparin | Urokinase may increase the anticoagulant activities of Semuloparin. |
| Idraparinux | Urokinase may increase the anticoagulant activities of Idraparinux. |
| Cangrelor | Urokinase may increase the anticoagulant activities of Cangrelor. |
| Astaxanthin | Urokinase may increase the anticoagulant activities of Astaxanthin. |
| Otamixaban | Urokinase may increase the anticoagulant activities of Otamixaban. |
| Amediplase | Urokinase may increase the anticoagulant activities of Amediplase. |
| Danaparoid | Urokinase may increase the anticoagulant activities of Danaparoid. |
| Dalteparin | Urokinase may increase the anticoagulant activities of Dalteparin. |
| Tinzaparin | Urokinase may increase the anticoagulant activities of Tinzaparin. |
| (R)-warfarin | Urokinase may increase the anticoagulant activities of (R)-warfarin. |
| Ethyl biscoumacetate | Urokinase may increase the anticoagulant activities of Ethyl biscoumacetate. |
| Nadroparin | Urokinase may increase the anticoagulant activities of Nadroparin. |
| Triflusal | Urokinase may increase the anticoagulant activities of Triflusal. |
| Ticagrelor | Urokinase may increase the anticoagulant activities of Ticagrelor. |
| Ditazole | Urokinase may increase the anticoagulant activities of Ditazole. |
| Vorapaxar | Urokinase may increase the anticoagulant activities of Vorapaxar. |
| Sodium citrate | Urokinase may increase the anticoagulant activities of Sodium citrate. |
| Dextran | Urokinase may increase the anticoagulant activities of Dextran. |
| Bemiparin | Urokinase may increase the anticoagulant activities of Bemiparin. |
| Parnaparin | Urokinase may increase the anticoagulant activities of Parnaparin. |
| Desirudin | Urokinase may increase the anticoagulant activities of Desirudin. |
| Antithrombin Alfa | Urokinase may increase the anticoagulant activities of Antithrombin Alfa. |
| Protein C | Urokinase may increase the anticoagulant activities of Protein C. |
| Antithrombin III human | Urokinase may increase the anticoagulant activities of Antithrombin III human. |
| Letaxaban | Urokinase may increase the anticoagulant activities of Letaxaban. |
| Darexaban | Urokinase may increase the anticoagulant activities of Darexaban. |
| Betrixaban | Urokinase may increase the anticoagulant activities of Betrixaban. |
| Nafamostat | Urokinase may increase the anticoagulant activities of Nafamostat. |
| Monteplase | Urokinase may increase the anticoagulant activities of Monteplase. |
| Gabexate | Urokinase may increase the anticoagulant activities of Gabexate. |
| Fluindione | Urokinase may increase the anticoagulant activities of Fluindione. |
| Protein S human | Urokinase may increase the anticoagulant activities of Protein S human. |
| Brinase | Urokinase may increase the anticoagulant activities of Brinase. |
| Clorindione | Urokinase may increase the anticoagulant activities of Clorindione. |
| Diphenadione | Urokinase may increase the anticoagulant activities of Diphenadione. |
| Tioclomarol | Urokinase may increase the anticoagulant activities of Tioclomarol. |
| Melagatran | Urokinase may increase the anticoagulant activities of Melagatran. |
| Saruplase | Urokinase may increase the anticoagulant activities of Saruplase. |
| (S)-Warfarin | Urokinase may increase the anticoagulant activities of (S)-Warfarin. |
| Tocopherylquinone | Urokinase may increase the anticoagulant activities of Tocopherylquinone. |
| Dabigatran | Urokinase may increase the anticoagulant activities of Dabigatran. |
| Edetic acid | Urokinase may increase the anticoagulant activities of Edetic acid. |
| Troxerutin | Urokinase may increase the anticoagulant activities of Troxerutin. |
| Reviparin | Urokinase may increase the anticoagulant activities of Reviparin. |
| Dermatan sulfate | Urokinase may increase the anticoagulant activities of Dermatan sulfate. |