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Exagamglogene autotemcel Approved DB15572
biotech

Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death.…

Kategori:
Autologous Cultured CellBlood and Blood Forming Organs
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Voxelotor Approved DB14975
small molecule | CAS: 1446321-46-5

Voxelotor is a novel hemoglobin S polymerization inhibitor for the treatment of sickle cell disease. This is a genetically inherited condition most prevalent in the Middle East, Africa, and certain parts of India. Sickle cell disease can lead to excruciating …

Kategori:
AldehydesBlood and Blood Forming OrgansCytochrome P-450 CYP2B6 Substrates +7
Target Protein:
Hemoglobin subunit alpha
Waktu ParuhThe plasma eliminat…
Vol. DistribusiThe apparent volume…
KlirensThe apparent oral c…
Genetik -