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Total database: 17430
Struktur (SMILES)
4 (100.0%)
Target
3 (75.0%)
Genomik
2 (50.0%)
Referensi
4 (100.0%)

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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (4)

Arverapamil DB06669
small molecule | CAS: 123932-43-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Dexverapamil DB14063
small molecule | CAS: 38321-02-7

Deskripsi belum tersedia.

Kategori:
Agents causing hyperkalemiaAminesAntiarrhythmic agents +14
Target Protein:
ATP-dependent translocase ABCB1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Diltiazem Approved DB00343
small molecule | CAS: 42399-41-7

Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it prim…

Kategori:
Agents causing hyperkalemiaAgents for Treatment of Hemorrhoids and Anal Fissures for Topical UseAntiarrhythmic agents +44
Target Protein:
Voltage-dependent L-type calcium channel subunit alpha-1CVoltage-dependent calcium channel subunit alpha-2/delta-1Voltage-dependent calcium channel gamma-1 subunit
Gen Terkait:
ADRB1
Waktu ParuhThe plasma eliminat…
Vol. DistribusiThe apparent volume…
KlirensFollowing a single …
Genetik 1 Varian
Verapamil Approved DB00661
small molecule | CAS: 52-53-9

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early 1960s.[A188514] It is a member …

Kategori:
ACE Inhibitors and Calcium Channel BlockersAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists +50
Target Protein:
Voltage-dependent L-type calcium channel subunit alpha-1CVoltage-dependent N-type calcium channel subunit alpha-1BVoltage-dependent P/Q-type calcium channel subunit alpha-1A +10
Gen Terkait:
ADRB1
Waktu ParuhSingle-dose studies…
Vol. DistribusiVerapamil has a ste…
KlirensSystemic clearance …
Genetik 1 Varian