Hasil Pencarian (2)
small molecule | CAS: 491833-29-5
Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease.[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid ?-glucosidase, an enzyme that converts glucosylcer…
Kategori:
Alimentary Tract and MetabolismCytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (strength unknown)
+15
Target Protein:
Ceramide glucosyltransferase
Waktu ParuhEliglustat has a te…
Vol. DistribusiIn CYP2D6 extensive…
KlirensIn healthy CYP2D6 e…
Genetik
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biotech | CAS: 884604-91-5
Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for us…
Kategori:
Alimentary Tract and MetabolismEnzymesEnzymes and Coenzymes
+1
Target Protein:
Lysosomal acid glucosylceramidase
Waktu Paruh11-12 minutes.
Vol. DistribusiThe mean volume of …
KlirensMean clearance rang…
Genetik
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