Hasil Pencarian (2)
small molecule | CAS: 330784-47-9
Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and [vardenafil] but less selectivity th…
Kategori:
BCRP/ABCG2 InhibitorsCytochrome P-450 CYP2C9 SubstratesCytochrome P-450 CYP3A Substrates
+9
Target Protein:
cGMP-specific 3',5'-cyclic phosphodiesterase
Waktu ParuhStudies have demons…
Vol. DistribusiThe apparent volume…
Klirens-
Genetik
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small molecule | CAS: 224785-90-4
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from n…
Kategori:
Cardiovascular AgentsCytochrome P-450 CYP2C19 InhibitorsCytochrome P-450 CYP2C19 Inhibitors (weak)
+30
Target Protein:
cGMP-specific 3',5'-cyclic phosphodiesteraseRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Waktu ParuhVardenafil and its …
Vol. DistribusiVardenafil has a st…
KlirensVardenafil has a to…
Genetik
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