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Total database: 17430
Struktur (SMILES)
6 (100.0%)
Target
6 (100.0%)
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Referensi
6 (100.0%)

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Hasil Pencarian (6)

Alcuronium DB13648
small molecule | CAS: 23214-96-2

A non-depolarizing skeletal muscle relaxant similar to [tubocurarine]. It is used as an anesthesia adjuvant.

Kategori:
Adjuvants, AnesthesiaAlkaloidsAmines +21
Target Protein:
Neuronal acetylcholine receptor subunit alpha-7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Gallamine triethiodide Approved DB00483
small molecule | CAS: 65-29-2

A synthetic nondepolarizing blocking drug. The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. It sho…

Kategori:
Agents producing tachycardiaAminesAnticholinergic Agents +12
Target Protein:
Muscarinic acetylcholine receptor M2AcetylcholinesteraseNeuronal acetylcholine receptor subunit alpha-2 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Metocurine Approved DB01336
small molecule | CAS: 5152-30-7

Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant. Patients on chronic anticonvulsant drugs are relatively resistant to metocurine. [A2393]

Kategori:
Agents producing tachycardiaAlkaloidsAmines +18
Target Protein:
Neuronal acetylcholine receptor subunit alpha-2Muscarinic acetylcholine receptor M2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Metocurine iodide Approved DB00416
small molecule | CAS: 7601-55-0

Metocurine iodide is a benzylisoquinolinium competitive nondepolarizing neuromuscular blocking agent. It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy Metocurine …

Kategori:
AlkaloidsAminesAnticholinergic Agents +12
Target Protein:
Neuronal acetylcholine receptor subunit alpha-4Neuronal acetylcholine receptor subunit beta-2Neuronal acetylcholine receptor subunit alpha-2
Waktu Paruh3 to 4 hours
Vol. Distribusi-
Klirens-
Genetik -
Neostigmine Approved DB01400
small molecule | CAS: 59-99-4

A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.

Kategori:
AminesAntiglaucoma Preparations and MioticsAutonomic Agents +13
Target Protein:
Acetylcholinesterase
Waktu ParuhThe half-life range…
Vol. Distribusi-
Klirens-
Genetik -
Tubocurarine Approved DB01199
small molecule | CAS: 57-95-4

Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid.[A216008] Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and dart…

Kategori:
AlkaloidsAminesAnticholinergic Agents +23
Target Protein:
Neuronal acetylcholine receptor subunit alpha-25-hydroxytryptamine receptor 3AAcetylcholinesterase +1
Waktu Paruh1-2 hours
Vol. Distribusi-
Klirens-
Genetik -